Tommaso Sconocchia

Division of Hematology,
Department of Internal Medicine,
Division of Hematology, Department of Internal Medicine

Medical University of Graz

BIOGRAPHY

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PUBLICATIONS

Recent perspective on CAR and Fcγ-CR T cell immunotherapy for cancers: Preclinical evidence versus clinical outcomes.

Biochemical pharmacology Aug, 2019 | Pubmed ID: 31176617

CD16-158-valine chimeric receptor T cells overcome the resistance of KRAS-mutated colorectal carcinoma cells to cetuximab.

International journal of cancer May, 2020 | Pubmed ID: 31396956

In vitro elimination of epidermal growth factor receptor-overexpressing cancer cells by CD32A-chimeric receptor T cells in combination with cetuximab or panitumumab.

International journal of cancer Jan, 2020 | Pubmed ID: 31479522

BMP7 aberrantly induced in the psoriatic epidermis instructs inflammation-associated Langerhans cells.

The Journal of allergy and clinical immunology Apr, 2020 | Pubmed ID: 31870764

Bone morphogenetic protein signaling regulates skin inflammation via modulating dendritic cell function.

The Journal of allergy and clinical immunology May, 2021 | Pubmed ID: 33250156

Induction of the sphingosine-1-phosphate signaling pathway by TGF-β1 during Langerhans-type dendritic cell differentiation.

European journal of immunology Jul, 2021 | Pubmed ID: 33768654

The miR-424(322)/503 gene cluster regulates pro- versus anti-inflammatory skin DC subset differentiation by modulating TGF-β signaling.

Cell reports Apr, 2021 | Pubmed ID: 33910004

Regulation of the Immune System in Health and Disease by Members of the Bone Morphogenetic Protein Family.

Frontiers in immunology , 2021 | Pubmed ID: 34925388

Immunotherapy as a Turning Point in the Treatment of Acute Myeloid Leukemia.

Cancers Dec, 2021 | Pubmed ID: 34944865

Immunomodulatory Effects of Aronia Juice Polyphenols-Results of a Randomized Placebo-Controlled Human Intervention Study and Cell Culture Experiments.

Antioxidants (Basel, Switzerland) Jun, 2022 | Pubmed ID: 35883769

Direct CD32 T-cell cytotoxicity: implications for breast cancer prognosis and treatment.

Life science alliance Dec, 2022 | Pubmed ID: 36241426

Human gene-engineered calreticulin mutant stem cells recapitulate MPN hallmarks and identify targetable vulnerabilities.

Leukemia Feb, 2023 | Pubmed ID: 36813992

INSTITUTIONS

Medical University of Graz

JOVE ARTICLES

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells

Tommaso Sconocchia¹,

Johannes Foßelteder¹,

Thomas Köhnke²,

Ravindra Majeti²,

Andreas Reinisch^1,3

¹Division of Hematology, Department of Internal Medicine, Medical University of Graz,

²Division of Hematology, Stanford Cancer Institute, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine,

³Department of Blood Group Serology and Transfusion Medicine, Medical University of Graz

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Tommaso Sconocchia

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Medical University of Graz

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells

Division of Hematology,
Department of Internal Medicine,
Division of Hematology, Department of Internal Medicine