Bioprocessing Technology Institute (BTI)
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Generation of high-level stable transgene expressing human embryonic stem cell lines using Chinese hamster elongation factor-1 alpha promoter system.
Stem cells and development Aug, 2008 | Pubmed ID: 18788934
Quantitative identification of teratoma tissues formed by human embryonic stem cells with TeratomEye.
Biotechnology letters May, 2009 | Pubmed ID: 19169887
Identification of cellular objective for elucidating the physiological state of plasmid-bearing Escherichia coli using genome-scale in silico analysis.
Biotechnology progress , 2009 | Pubmed ID: 19224555
Long-term microcarrier suspension cultures of human embryonic stem cells.
Stem cell research May, 2009 | Pubmed ID: 19393590
KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells.
Stem cells (Dayton, Ohio) Sep, 2009 | Pubmed ID: 19522013
Defined and serum-free media support undifferentiated human embryonic stem cell growth.
Stem cells and development Jun, 2010 | Pubmed ID: 19686051
Investigations into the metabolism of two-dimensional colony and suspended microcarrier cultures of human embryonic stem cells in serum-free media.
Stem cells and development Nov, 2010 | Pubmed ID: 20380517
Scalable platform for human embryonic stem cell differentiation to cardiomyocytes in suspended microcarrier cultures.
Tissue engineering. Part C, Methods Dec, 2010 | Pubmed ID: 20590381
Agitation can induce differentiation of human pluripotent stem cells in microcarrier cultures.
Tissue engineering. Part C, Methods Feb, 2011 | Pubmed ID: 20698747
Defining a threshold surface density of vitronectin for the stable expansion of human embryonic stem cells.
Tissue engineering. Part C, Methods Feb, 2011 | Pubmed ID: 20726687
Expansion of human embryonic stem cells on cellulose microcarriers.
Current protocols in stem cell biology Sep, 2010 | Pubmed ID: 20814936
Impact of vitronectin concentration and surface properties on the stable propagation of human embryonic stem cells.
Biointerphases Sep, 2010 | Pubmed ID: 21171706
Critical microcarrier properties affecting the expansion of undifferentiated human embryonic stem cells.
Stem cell research Sep, 2011 | Pubmed ID: 21763618
Distinct regulation of mitogen-activated protein kinase activities is coupled with enhanced cardiac differentiation of human embryonic stem cells.
Stem cell research Nov, 2011 | Pubmed ID: 21907163
Translating Human Embryonic Stem Cells from 2-Dimensional to 3-Dimensional Cultures in a Defined Medium on Laminin- and Vitronectin-Coated Surfaces.
Stem cells and development Dec, 2011 | Pubmed ID: 22034857
Activated T cells modulate immunosuppression by embryonic-and bone marrow-derived mesenchymal stromal cells through a feedback mechanism.
Cytotherapy Mar, 2012 | Pubmed ID: 22136295
Differentiation of human embryonic stem cells to cardiomyocytes on microcarrier cultures.
Current protocols in stem cell biology May, 2012 | Pubmed ID: 22605644
Microcarrier suspension cultures for high-density expansion and differentiation of human pluripotent stem cells to neural progenitor cells.
Tissue engineering. Part C, Methods Feb, 2013 | Pubmed ID: 22834957
Application of human mesenchymal and pluripotent stem cell microcarrier cultures in cellular therapy: achievements and future direction.
Biotechnology advances Nov, 2013 | Pubmed ID: 23531528
Inhibition of ROCK-myosin II signaling pathway enables culturing of human pluripotent stem cells on microcarriers without extracellular matrix coating.
Tissue engineering. Part C, Methods Mar, 2014 | Pubmed ID: 23777438
Time-resolved video analysis and management system for monitoring cardiomyocyte differentiation processes and toxicology assays.
Biotechnology journal May, 2014 | Pubmed ID: 24619905
Cationic surface charge combined with either vitronectin or laminin dictates the evolution of human embryonic stem cells/microcarrier aggregates and cell growth in agitated cultures.
Stem cells and development Jul, 2014 | Pubmed ID: 24641164
An intermittent rocking platform for integrated expansion and differentiation of human pluripotent stem cells to cardiomyocytes in suspended microcarrier cultures.
Stem cell research Sep, 2014 | Pubmed ID: 25043964
Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling.
Journal of molecular and cellular cardiology Mar, 2015 | Pubmed ID: 25528965
Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards.
Stem cells translational medicine Mar, 2015 | Pubmed ID: 25650438
Serum-free media formulations are cell line-specific and require optimization for microcarrier culture.
Cytotherapy Aug, 2015 | Pubmed ID: 26139547
Integrated processes for expansion and differentiation of human pluripotent stem cells in suspended microcarriers cultures.
Biochemical and biophysical research communications May, 2016 | Pubmed ID: 26385176
Recent advances in serum-free microcarrier expansion of mesenchymal stromal cells: Parameters to be optimized.
Biochemical and biophysical research communications May, 2016 | Pubmed ID: 26385177
Fabrication of uniform-sized poly-ɛ-caprolactone microspheres and their applications in human embryonic stem cell culture.
Biomedical microdevices Dec, 2015 | Pubmed ID: 26458560
Enhanced in vitro osteogenic differentiation of human fetal MSCs attached to 3D microcarriers versus harvested from 2D monolayers.
BMC biotechnology Oct, 2015 | Pubmed ID: 26520400
International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials.
Cytotherapy Feb, 2016 | Pubmed ID: 26724220
Expansion in microcarrier-spinner cultures improves the chondrogenic potential of human early mesenchymal stromal cells.
Cytotherapy Jun, 2016 | Pubmed ID: 27173750
Genome-Wide Transcriptome and Binding Sites Analyses Identify Early FOX Expressions for Enhancing Cardiomyogenesis Efficiency of hESC Cultures.
Scientific reports Aug, 2016 | Pubmed ID: 27501774
Biodegradable ECM-coated PCL microcarriers support scalable human early MSC expansion and in vivo bone formation.
Cytotherapy Oct, 2016 | Pubmed ID: 27503763
Biodegradable poly-ε-caprolactone microcarriers for efficient production of human mesenchymal stromal cells and secreted cytokines in batch and fed-batch bioreactors.
Cytotherapy Mar, 2017 | Pubmed ID: 28017598
Tunable Volumetric Density and Porous Structure of Spherical Poly-ε-caprolactone Microcarriers, as Applied in Human Mesenchymal Stem Cell Expansion.
Langmuir : the ACS journal of surfaces and colloids Mar, 2017 | Pubmed ID: 28221044
Critical attributes of human early mesenchymal stromal cell-laden microcarrier constructs for improved chondrogenic differentiation.
Stem cell research & therapy May, 2017 | Pubmed ID: 28482913
Identification of Na+/K+-ATPase inhibition-independent proarrhythmic ionic mechanisms of cardiac glycosides.
Scientific reports May, 2017 | Pubmed ID: 28550304
Erratum: Identification of Na/K-ATPase inhibition-independent proarrhythmic ionic mechanisms of cardiac glycosides.
Scientific reports Sep, 2017 | Pubmed ID: 28904341
Immobilization of vitronectin-binding heparan sulfates onto surfaces to support human pluripotent stem cells.
Journal of biomedical materials research. Part B, Applied biomaterials Jul, 2018 | Pubmed ID: 28941021
Improved erythroid differentiation of multiple human pluripotent stem cell lines in microcarrier culture by modulation of Wnt/β-Catenin signaling.
Haematologica Jul, 2018 | Pubmed ID: 29519863
Unraveling the Inconsistencies of Cardiac Differentiation Efficiency Induced by the GSK3β Inhibitor CHIR99021 in Human Pluripotent Stem Cells.
Stem cell reports Jun, 2018 | Pubmed ID: 29706502
Meticulous optimization of cardiomyocyte yields in a 3-stage continuous integrated agitation bioprocess.
Stem cell research Aug, 2018 | Pubmed ID: 30098478
Inertial-Based Filtration Method for Removal of Microcarriers from Mesenchymal Stem Cell Suspensions.
Scientific reports Aug, 2018 | Pubmed ID: 30127526
Review: In vitro generation of red blood cells for transfusion medicine: Progress, prospects and challenges.
Biotechnology advances Dec, 2018 | Pubmed ID: 30273713
Scaled-Up Inertial Microfluidics: Retention System for Microcarrier-Based Suspension Cultures.
Biotechnology journal May, 2019 | Pubmed ID: 30791214
Sub-confluent culture of human mesenchymal stromal cells on biodegradable polycaprolactone microcarriers enhances bone healing of rat calvarial defect.
Cytotherapy Jun, 2019 | Pubmed ID: 30975604
Rapid Detection of Senescent Mesenchymal Stromal Cells by a Fluorescent Probe.
Biotechnology journal Oct, 2019 | Pubmed ID: 31218816
Human mesenchymal stem cell therapy for cartilage repair: Review on isolation, expansion, and constructs.
Stem cell research Apr, 2020 | Pubmed ID: 32109723
Selection of human induced pluripotent stem cells lines optimization of cardiomyocytes differentiation in an integrated suspension microcarrier bioreactor.
Stem cell research & therapy Mar, 2020 | Pubmed ID: 32183888
Machine learning to predict mesenchymal stem cell efficacy for cartilage repair.
PLoS computational biology Oct, 2020 | Pubmed ID: 33027251
A Scalable Suspension Platform for Generating High-Density Cultures of Universal Red Blood Cells from Human Induced Pluripotent Stem Cells.
Stem cell reports Jan, 2021 | Pubmed ID: 33306988
Multiomics analyses of cytokines, genes, miRNA, and regulatory networks in human mesenchymal stem cells expanded in stirred microcarrier-spinner cultures.
Stem cell research May, 2021 | Pubmed ID: 33676128
Integrating Human-Induced Pluripotent Stem Cell Expansion Capability and Cardiomyocyte Differentiation Potential in a Microcarrier Suspension Culture.
Methods in molecular biology (Clifton, N.J.) , 2022 | Pubmed ID: 34519977
Industrially Compatible Transfusable iPSC-Derived RBCs: Progress, Challenges and Prospective Solutions.
International journal of molecular sciences Sep, 2021 | Pubmed ID: 34575977
Strategies to enhance immunomodulatory properties and reduce heterogeneity in mesenchymal stromal cells during ex vivo expansion.
Cytotherapy May, 2022 | Pubmed ID: 35227601
Selection of O-negative induced pluripotent stem cell clones for high-density red blood cell production in a scalable perfusion bioreactor system.
Cell proliferation Aug, 2022 | Pubmed ID: 35289971
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