Division of Oncology,
Department of Pediatrics,
Division of Oncology, Department of Pediatrics
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Transplantable marrow osteoprogenitors engraft in discrete saturable sites in the marrow microenvironment.
Experimental hematology Mar, 2008 | Pubmed ID: 18179857
Donor cell-derived osteopoiesis originates from a self-renewing stem cell with a limited regenerative contribution after transplantation.
Blood Apr, 2008 | Pubmed ID: 18182575
Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation.
Blood Sep, 2009 | Pubmed ID: 19433859
A strategy for single nucleotide polymorphism analysis of chimerism for somatic cell therapy.
Cytotherapy Dec, 2010 | Pubmed ID: 20429790
Osteopoietic engraftment after bone marrow transplantation: effect of inbred strain of mice.
Experimental hematology Sep, 2010 | Pubmed ID: 20447443
Cytokine-induced osteopoietic differentiation of transplanted marrow cells.
Blood Aug, 2011 | Pubmed ID: 21715305
Transplanted bone marrow mononuclear cells and MSCs impart clinical benefit to children with osteogenesis imperfecta through different mechanisms.
Blood Aug, 2012 | Pubmed ID: 22829629
Improved isolation and expansion of bone marrow mesenchymal stromal cells using a novel marrow filter device.
Cytotherapy Feb, 2013 | Pubmed ID: 23321326
Transplanted murine long-term repopulating hematopoietic cells can differentiate to osteoblasts in the marrow stem cell niche.
Molecular therapy : the journal of the American Society of Gene Therapy Jun, 2013 | Pubmed ID: 23587920
Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning.
Blood Jun, 2013 | Pubmed ID: 23667055
IGF-1-mediated osteoblastic niche expansion enhances long-term hematopoietic stem cell engraftment after murine bone marrow transplantation.
Stem cells (Dayton, Ohio) Oct, 2013 | Pubmed ID: 23818291
Delayed marrow infusion in mice enhances hematopoietic and osteopoietic engraftment by facilitating transient expansion of the osteoblastic niche.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation Nov, 2013 | Pubmed ID: 23916672
Tendon progenitor cells in injured tendons have strong chondrogenic potential: the CD105-negative subpopulation induces chondrogenic degeneration.
Stem cells (Dayton, Ohio) Dec, 2014 | Pubmed ID: 25220576
Genomic and functional comparison of mesenchymal stromal cells prepared using two isolation methods.
Cytotherapy Mar, 2015 | Pubmed ID: 25659640
Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy.
Cancer discovery Dec, 2015 | Pubmed ID: 26516065
Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies.
The Journal of clinical investigation Aug, 2016 | Pubmed ID: 27571406
Hematopoietic derived cells do not contribute to osteogenesis as osteoblasts.
Bone Jan, 2017 | Pubmed ID: 27725318
Monocyte lineage-derived IL-6 does not affect chimeric antigen receptor T-cell function.
Cytotherapy 07, 2017 | Pubmed ID: 28506444
Extracellular vesicles released from mesenchymal stromal cells stimulate bone growth in osteogenesis imperfecta.
Cytotherapy Jan, 2018 | Pubmed ID: 29107738
Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response.
Human gene therapy Feb, 2019 | Pubmed ID: 30024272
Rene Machietto1,
Nicholas Giacobbe1,
Jessica Perazzelli2,
Ted J. Hofmann2,
Allison Barz Leahy2,3,
Stephan A. Grupp1,2,3,
Yongping Wang1,3,4,
Stephan Kadauke1,3,4
1Cell and Gene Therapy Laboratory, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia,
2Division of Oncology, Department of Pediatrics, Children’s Hospital of Philadelphia,
3, Perelman School of Medicine at the University of Pennsylvania,
4Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia
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