Department of Surgery
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Vessel bioengineering.
Circulation journal : official journal of the Japanese Circulation Society Dec, 2013 | Pubmed ID: 24334558
Regenerative implants for cardiovascular tissue engineering.
Translational research : the journal of laboratory and clinical medicine Apr, 2014 | Pubmed ID: 24589506
Characterization of evolving biomechanical properties of tissue engineered vascular grafts in the arterial circulation.
Journal of biomechanics Jun, 2014 | Pubmed ID: 24702863
Evaluation of remodeling process in small-diameter cell-free tissue-engineered arterial graft.
Journal of vascular surgery Apr, 2014 | Pubmed ID: 24745941
Comparison of a Closed System to a Standard Open Technique for Preparing Tissue Engineered Vascular Grafts.
Tissue engineering. Part C, Methods May, 2014 | Pubmed ID: 24866863
Targeted imaging of matrix metalloproteinase activity in the evaluation of remodeling tissue-engineered vascular grafts implanted in a growing lamb model.
The Journal of thoracic and cardiovascular surgery Nov, 2014 | Pubmed ID: 24952823
A hypothesis-driven parametric study of effects of polymeric scaffold properties on tissue engineered neovessel formation.
Acta biomaterialia Jan, 2015 | Pubmed ID: 25288519
Comparison of the biological equivalence of two methods for isolating bone marrow mononuclear cells for fabricating tissue-engineered vascular grafts.
Tissue engineering. Part C, Methods Jun, 2015 | Pubmed ID: 25397868
Well-organized neointima of large-pore poly(L-lactic acid) vascular graft coated with poly(L-lactic-co-ε-caprolactone) prevents calcific deposition compared to small-pore electrospun poly(L-lactic acid) graft in a mouse aortic implantation model.
Atherosclerosis Dec, 2014 | Pubmed ID: 25463106
TGFβR1 inhibition blocks the formation of stenosis in tissue-engineered vascular grafts.
Journal of the American College of Cardiology Feb, 2015 | Pubmed ID: 25660932
Biomechanical diversity despite mechanobiological stability in tissue engineered vascular grafts two years post-implantation.
Tissue engineering. Part A May, 2015 | Pubmed ID: 25710791
The innate immune system contributes to tissue-engineered vascular graft performance.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun, 2015 | Pubmed ID: 25713026
Development of small diameter nanofiber tissue engineered arterial grafts.
PloS one , 2015 | Pubmed ID: 25830942
Hemodynamic Characterization of a Mouse Model for Investigating the Cellular and Molecular Mechanisms of Neotissue Formation in Tissue-Engineered Heart Valves.
Tissue engineering. Part C, Methods Sep, 2015 | Pubmed ID: 25915105
C-Cell Neoplasia in Asymptomatic Carriers of RET Mutation in Extracellular Cysteine-Rich and Intracellular Tyrosine Kinase Domain.
Human pathology Aug, 2015 | Pubmed ID: 26033033
Cilostazol, Not Aspirin, Prevents Stenosis of Bioresorbable Vascular Grafts in a Venous Model.
Arteriosclerosis, thrombosis, and vascular biology Sep, 2015 | Pubmed ID: 26183618
Influence of Posttransplant Lymphoproliferative Disorder on Survival in Children After Heart Transplantation.
Pediatric cardiology Dec, 2015 | Pubmed ID: 26187515
A mouse model of endocardial fibroelastosis.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology Nov-Dec, 2015 | Pubmed ID: 26363814
Effect of cell seeding on neotissue formation in a tissue engineered trachea.
Journal of pediatric surgery Jan, 2016 | Pubmed ID: 26552897
Cardiovascular Tissue Engineering: Preclinical Validation to Bedside Application.
Physiology (Bethesda, Md.) Jan, 2016 | Pubmed ID: 26661524
Long-Term Functional Efficacy of a Novel Electrospun Poly(Glycerol Sebacate)-Based Arterial Graft in Mice.
Annals of biomedical engineering 08, 2016 | Pubmed ID: 26795977
Rational design of an improved tissue-engineered vascular graft: determining the optimal cell dose and incubation time.
Regenerative medicine Mar, 2016 | Pubmed ID: 26925512
TGF-β receptor 1 inhibition prevents stenosis of tissue-engineered vascular grafts by reducing host mononuclear phagocyte activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2016 | Pubmed ID: 27059717
Novel Bioresorbable Vascular Graft With Sponge-Type Scaffold as a Small-Diameter Arterial Graft.
The Annals of thoracic surgery Sep, 2016 | Pubmed ID: 27154152
Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines.
Stem cell reports 06, 2016 | Pubmed ID: 27185282
Pilot Mouse Study of 1 mm Inner Diameter (ID) Vascular Graft Using Electrospun Poly(ester urea) Nanofibers.
Advanced healthcare materials 09, 2016 | Pubmed ID: 27390286
Clinical Translation of Tissue Engineered Trachea Grafts.
The Annals of otology, rhinology, and laryngology Nov, 2016 | Pubmed ID: 27411362
Tissue-Engineered Small Diameter Arterial Vascular Grafts from Cell-Free Nanofiber PCL/Chitosan Scaffolds in a Sheep Model.
PloS one , 2016 | Pubmed ID: 27467821
Impaired von Willebrand factor adhesion and platelet response in thrombospondin-2 knockout mice.
Blood 09, 2016 | Pubmed ID: 27471233
Fast-degrading bioresorbable arterial vascular graft with high cellular infiltration inhibits calcification of the graft.
Journal of vascular surgery 07, 2017 | Pubmed ID: 27687327
Objective characterization of airway dimensions using image processing.
International journal of pediatric otorhinolaryngology Dec, 2016 | Pubmed ID: 27863622
Tissue-engineered cardiac patch seeded with human induced pluripotent stem cell derived cardiomyocytes promoted the regeneration of host cardiomyocytes in a rat model.
Journal of cardiothoracic surgery Dec, 2016 | Pubmed ID: 27906085
Preclinical study of patient-specific cell-free nanofiber tissue-engineered vascular grafts using 3-dimensional printing in a sheep model.
The Journal of thoracic and cardiovascular surgery Apr, 2017 | Pubmed ID: 27938900
Tropoelastin inhibits intimal hyperplasia of mouse bioresorbable arterial vascular grafts.
Acta biomaterialia 04, 2017 | Pubmed ID: 28025048
Intravascular Ultrasound Characterization of a Tissue-Engineered Vascular Graft in an Ovine Model.
Journal of cardiovascular translational research Apr, 2017 | Pubmed ID: 28097523
The Heart and Great Vessels.
Cold Spring Harbor perspectives in medicine Mar, 2018 | Pubmed ID: 28289246
Endoscopic management of tissue-engineered tracheal graft stenosis in an ovine model.
The Laryngoscope 10, 2017 | Pubmed ID: 28349659
Role of Bone Marrow Mononuclear Cell Seeding for Nanofiber Vascular Grafts.
Tissue engineering. Part A Jun, 2017 | Pubmed ID: 28486019
The role of myeloid cell-derived PDGF-B in neotissue formation in a tissue-engineered vascular graft.
Regenerative medicine 04, 2017 | Pubmed ID: 28524773
Stress Analysis-Driven Design of Bilayered Scaffolds for Tissue-Engineered Vascular Grafts.
Journal of biomechanical engineering Dec, 2017 | Pubmed ID: 28886204
Deconstructing the Tissue Engineered Vascular Graft: Evaluating Scaffold Pre-Wetting, Conditioned Media Incubation, and Determining the Optimal Mononuclear Cell Source.
ACS biomaterials science & engineering , 2017 | Pubmed ID: 29226239
Designing a tissue-engineered tracheal scaffold for preclinical evaluation.
International journal of pediatric otorhinolaryngology Jan, 2018 | Pubmed ID: 29287858
Tissue-Engineered Heart Valves: A Call for Mechanistic Studies.
Tissue engineering. Part B, Reviews 06, 2018 | Pubmed ID: 29327671
Tissue-engineered Vascular Grafts in Children With Congenital Heart Disease: Intermediate Term Follow-up.
Seminars in thoracic and cardiovascular surgery , 2018 | Pubmed ID: 29427773
Intratumoral Delivery of Interferonγ-Secreting Mesenchymal Stromal Cells Repolarizes Tumor-Associated Macrophages and Suppresses Neuroblastoma Proliferation In Vivo.
Stem cells (Dayton, Ohio) 06, 2018 | Pubmed ID: 29430789
Oversized Biodegradable Arterial Grafts Promote Enhanced Neointimal Tissue Formation.
Tissue engineering. Part A Aug, 2018 | Pubmed ID: 29431029
Toward a patient-specific tissue engineered vascular graft.
Journal of tissue engineering , 2018 | Pubmed ID: 29568478
Quantification of tissue-engineered trachea performance with computational fluid dynamics.
The Laryngoscope Aug, 2018 | Pubmed ID: 29756207
Bone marrow-derived mononuclear cell seeded bioresorbable vascular graft improves acute graft patency by inhibiting thrombus formation via platelet adhesion.
International journal of cardiology Sep, 2018 | Pubmed ID: 29887474
Angiotensin II receptor I blockade prevents stenosis of tissue engineered vascular grafts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun, 2018 | Pubmed ID: 29906242
Magnetic Resonance Imaging of Shear Stress and Wall Thickness in Tissue-Engineered Vascular Grafts.
Tissue engineering. Part C, Methods 08, 2018 | Pubmed ID: 29978768
Clinical validation and reproducibility of endoscopic airway measurement in pediatric aerodigestive evaluation.
International journal of pediatric otorhinolaryngology Jan, 2019 | Pubmed ID: 30554710
Implantation of VEGF-functionalized cell-free vascular grafts: regenerative and immunological response.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 04, 2019 | Pubmed ID: 30629890
Mouse Model of Tracheal Replacement With Electrospun Nanofiber Scaffolds.
The Annals of otology, rhinology, and laryngology Jan, 2019 | Pubmed ID: 30700095
Factors Influencing Poor Outcomes in Synthetic Tissue-Engineered Tracheal Replacement.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 09, 2019 | Pubmed ID: 31035858
Early natural history of neotissue formation in tissue-engineered vascular grafts in a murine model.
Regenerative medicine 05, 2019 | Pubmed ID: 31180275
Differential outcomes of venous and arterial tissue engineered vascular grafts highlight the importance of coupling long-term implantation studies with computational modeling.
Acta biomaterialia 08, 2019 | Pubmed ID: 31200116
Optimization of Tissue-Engineered Vascular Graft Design Using Computational Modeling.
Tissue engineering. Part C, Methods 10, 2019 | Pubmed ID: 31218941
Degradation and evaluation of polycaprolactone, poly(ε-caprolactone-co-L-lactide), and poly-L-lactic acid as scaffold sealant polymers for murine tissue-engineered vascular grafts.
Regenerative medicine 07, 2019 | Pubmed ID: 31342857
Deconstructing tissue engineered trachea: Assessing the role of synthetic scaffolds, segmental replacement and cell seeding on graft performance.
Acta biomaterialia 01, 2020 | Pubmed ID: 31707085
Different degradation rates of nanofiber vascular grafts in small and large animal models.
Journal of tissue engineering and regenerative medicine 02, 2020 | Pubmed ID: 31756767
Fetal Transcatheter Trileaflet Heart Valve Hemodynamics: Implications of Scaling on Valve Mechanics and Turbulence.
Annals of biomedical engineering Jun, 2020 | Pubmed ID: 32052320
A computational bio-chemo-mechanical model of in vivo tissue-engineered vascular graft development.
Integrative biology : quantitative biosciences from nano to macro 04, 2020 | Pubmed ID: 32222759
Spontaneous reversal of stenosis in tissue-engineered vascular grafts.
Science translational medicine 04, 2020 | Pubmed ID: 32238576
The evaluation of a tissue-engineered cardiac patch seeded with hips derived cardiac progenitor cells in a rat left ventricular model.
PloS one , 2020 | Pubmed ID: 32511282
Spatial and Temporal Analysis of Host Cells in Tracheal Graft Implantation.
The Laryngoscope 02, 2021 | Pubmed ID: 32521060
The effect of pore diameter on neo-tissue formation in electrospun biodegradable tissue-engineered arterial grafts in a large animal model.
Acta biomaterialia 10, 2020 | Pubmed ID: 32822820
Electrospun Tissue-Engineered Arterial Graft Thickness Affects Long-Term Composition and Mechanics.
Tissue engineering. Part A 05, 2021 | Pubmed ID: 32854586
Development of Tissue Engineered Heart Valves for Percutaneous Transcatheter Delivery in a Fetal Ovine Model.
JACC. Basic to translational science Aug, 2020 | Pubmed ID: 32875171
Improvement of a Novel Small-diameter Tissue-engineered Arterial Graft With Heparin Conjugation.
The Annals of thoracic surgery 04, 2021 | Pubmed ID: 32946845
Effects of Braiding Parameters on Tissue Engineered Vascular Graft Development.
Advanced healthcare materials 12, 2020 | Pubmed ID: 33063452
Tissue Engineered Vascular Graft Recipient Interleukin 10 Status Is Critical for Preventing Thrombosis.
Advanced healthcare materials 12, 2020 | Pubmed ID: 33073543
Evaluating the Longevity of the Fontan Pathway.
Pediatric cardiology Dec, 2020 | Pubmed ID: 33161457
Biology and Biomechanics of the Heart Valve Extracellular Matrix.
Journal of cardiovascular development and disease Dec, 2020 | Pubmed ID: 33339213
Tissue engineering: Relevance to neonatal congenital heart disease.
Seminars in fetal & neonatal medicine Feb, 2021 | Pubmed ID: 33674254
Current Challenges and Solutions to Tissue Engineering of Large-scale Cardiac Constructs.
Current cardiology reports 03, 2021 | Pubmed ID: 33733317
Sex and Tamoxifen confound murine experimental studies in cardiovascular tissue engineering.
Scientific reports Apr, 2021 | Pubmed ID: 33850181
Tracheal Macrophages During Regeneration and Repair of Long-Segment Airway Defects.
The Laryngoscope Jun, 2021 | Pubmed ID: 34153127
Regeneration of partially decellularized tracheal scaffolds in a mouse model of orthotopic tracheal replacement.
Journal of tissue engineering Jan-Dec, 2021 | Pubmed ID: 34164107
Imatinib attenuates neotissue formation during vascular remodeling in an arterial bioresorbable vascular graft.
JVS-vascular science , 2020 | Pubmed ID: 34223286
On the shape and structure of the murine pulmonary heart valve.
Scientific reports Jul, 2021 | Pubmed ID: 34234231
Hemodynamic performance of tissue-engineered vascular grafts in Fontan patients.
NPJ Regenerative medicine Jul, 2021 | Pubmed ID: 34294733
Publisher Correction: Hemodynamic performance of tissue-engineered vascular grafts in Fontan patients.
NPJ Regenerative medicine Aug, 2021 | Pubmed ID: 34385470
Modulation of Synthetic Tracheal Grafts with Extracellular Matrix Coatings.
Bioengineering (Basel, Switzerland) Aug, 2021 | Pubmed ID: 34436119
Zoledronate alters natural progression of tissue-engineered vascular grafts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2021 | Pubmed ID: 34473380
The lysosomal trafficking regulator is necessary for normal wound healing.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society Jan, 2022 | Pubmed ID: 34837653
Fibrocytes: A Critical Review and Practical Guide.
Frontiers in immunology , 2021 | Pubmed ID: 34975874
Antibody-suppressor CXCR5 CD8 T cellular therapy ameliorates antibody-mediated rejection following kidney transplant in CCR5 KO mice.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Jun, 2022 | Pubmed ID: 35114045
The Potential Role of Regenerative Medicine on the Future Management of Hypoplastic Left Heart Syndrome.
Journal of cardiovascular development and disease Apr, 2022 | Pubmed ID: 35448083
Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth.
Communications medicine , 2022 | Pubmed ID: 35603301
A Multimodal Approach to Quantify Chondrocyte Viability for Airway Tissue Engineering.
The Laryngoscope Mar, 2023 | Pubmed ID: 35612419
Tissue-engineered composite tracheal grafts create mechanically stable and biocompatible airway replacements.
Journal of tissue engineering , 2022 | Pubmed ID: 35782992
Monocyte Recruitment for Vascular Tissue Regeneration.
Advanced healthcare materials Nov, 2022 | Pubmed ID: 36112115
Rapid Regeneration of a Neoartery with Elastic Lamellae.
Advanced materials (Deerfield Beach, Fla.) Nov, 2022 | Pubmed ID: 36120809
Tamoxifen reduces silicone implant capsule formation in a mouse model.
FASEB bioAdvances Oct, 2022 | Pubmed ID: 36238364
Computational analysis of serum-derived extracellular vesicle miRNAs in juvenile sheep model of single stage Fontan procedure.
Extracellular vesicle Dec, 2022 | Pubmed ID: 36330420
Tissue Engineering of Vascular Grafts: A Case Report From Bench to Bedside and Back.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2023 | Pubmed ID: 36633008
Implanted Tissue-Engineered Vascular Graft Cell Isolation with Single-Cell RNA Sequencing Analysis.
Tissue engineering. Part C, Methods Feb, 2023 | Pubmed ID: 36719780
Patch Materials for Pulmonary Artery Arterioplasty and Right Ventricular Outflow Tract Augmentation: A Review.
Pediatric cardiology Jun, 2023 | Pubmed ID: 37149833
Regeneration of tracheal neotissue in partially decellularized scaffolds.
NPJ Regenerative medicine Jul, 2023 | Pubmed ID: 37438368
Functional mechanical behavior of the murine pulmonary heart valve.
Scientific reports Aug, 2023 | Pubmed ID: 37553466
Assessing the Biocompatibility and Regeneration of Electrospun-Nanofiber Composite Tracheal Grafts.
The Laryngoscope Aug, 2023 | Pubmed ID: 37578209
Qiang Zeng1,
Doug A. Gouchoe2,3,
Mahboubeh Nabavinia4,
Yong Gyu Lee2,
Xi Wang2,
Terri A. Shaffer5,
Mitchel R. Stacy4,5,6,
Blake R. Peterson7,8,
Bryan A. Whitson2,9,
Christopher Breuer1,4,
Sylvester M. Black1,10
1Department of Surgery, Nationwide Children’s Hospital,
2COPPER Laboratory, The Ohio State University,
388th Surgical Operation Operations Squadron, WPAFB,
4Center for Regenerative Medicine, The Research Institute at Nationwide Children’s Hospital,
5Division of Vascular Diseases and Surgery, The Ohio State University College of Medicine,
6Interdisciplinary Biophysics Graduate Program, The Ohio State University,
7Division of Medicinal Chemistry and Pharmacognosy, The Ohio State University College of Pharmacy,
8, The Ohio State University Comprehensive Cancer Center,
9Division of Cardiac Surgery, Department of Surgery, The Ohio State Wexner Medical Center,
10Division of Transplantation, Department of Surgery, The Ohio State Wexner Medical Center
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