D.A. Lydall

The Walker 256 carcinoma: a cell type inherently sensitive only to those difunctional agents that can form DNA interstrand crosslinks.

A new role for MCM1 in yeast: cell cycle regulation of SW15 transcription.

Changes in a SWI4,6-DNA-binding complex occur at the time of HO gene activation in yeast.

The identification of a second cell cycle control on the HO promoter in yeast: cell cycle regulation of SW15 nuclear entry.

Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum(II) and cis-diammine-(1,1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA.

The effect of monofunctional or difunctional platinum adducts and of various other associated DNA damage on the expression of transfected DNA in mammalian cell lines sensitive or resistant to difunctional agents.

Yeast checkpoint genes in DNA damage processing: implications for repair and arrest.

Cell cycle checkpoints, genetic instability and cancer.

From DNA damage to cell cycle arrest and suicide: a budding yeast perspective.

A meiotic recombination checkpoint controlled by mitotic checkpoint genes.

Use of cdc13-1-induced DNA damage to study effects of checkpoint genes on DNA damage processing.

G2/M checkpoint genes of Saccharomyces cerevisiae: further evidence for roles in DNA replication and/or repair.

NDD1, a high-dosage suppressor of cdc28-1N, is essential for expression of a subset of late-S-phase-specific genes in Saccharomyces cerevisiae.

Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction.

EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants.

Hiding at the ends of yeast chromosomes: telomeres, nucleases and checkpoint pathways.

A domain of Rad9 specifically required for activation of Chk1 in budding yeast.

Mec1 and Rad53 inhibit formation of single-stranded DNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants.

EXO1 plays a role in generating type I and type II survivors in budding yeast.

Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants.

Telomerase- and recombination-independent immortalization of budding yeast.

The PAL-mechanism of chromosome maintenance: causes and consequences.

Chromatin and the DNA damage response.

Pulsed-field gel electrophoresis of budding yeast chromosomes.

A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator.

Positional cloning of a cyromazine resistance gene in Drosophila melanogaster.

MRX protects telomeric DNA at uncapped telomeres of budding yeast cdc13-1 mutants.

Linear chromosome maintenance in the absence of essential telomere-capping proteins.

Detecting repair intermediates in vivo: effects of DNA damage response genes on single-stranded DNA accumulation at uncapped telomeres in budding yeast.

Modelling the checkpoint response to telomere uncapping in budding yeast.

MTAS: Mental health of applicants seems to be deteriorating.

Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1.

Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres.

Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response.

A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection.

A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae.

Psychological impact of systemic training failure on mental health and career satisfaction of UK trainees: lessons from an online attitudes survey.

Telomere maintenance and survival in saccharomyces cerevisiae in the absence of telomerase and RAD52.

Taming the tiger by the tail: modulation of DNA damage responses by telomeres.

Support of association between BRD1 and both schizophrenia and bipolar affective disorder.

Analysis of licking microstructure provides no evidence for a reduction in reward value following acute or sub-chronic phencyclidine administration.

Colonyzer: automated quantification of micro-organism growth characteristics on solid agar.

Telomere replication: Mre11 leads the way.

Survival and growth of yeast without telomere capping by Cdc13 in the absence of Sgs1, Exo1, and Rad9.

Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping.

Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample.

Simultaneous contrast: evidence from licking microstructure and cross-solution comparisons.

Lack of allelic association between markers at the DRD2 and ANKK1 gene loci with the alcohol-dependence syndrome and criminal activity.

Customizable views on semantically integrated networks for systems biology.

Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects.

Genetic association study of GABRA2 single nucleotide polymorphisms and electroencephalography in alcohol dependence.

Confirmation of prior evidence of genetic susceptibility to alcoholism in a genome-wide association study of comorbid alcoholism and bipolar disorder.

Similarities and differences between "uncapped" telomeres and DNA double-strand breaks.

Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast.

Choice of antipsychotic treatment by European psychiatry trainees: are decisions based on evidence?