Yu Xiao

Shenzhen Research Institute, wuhan university

Affiliated withwuhan university University of Pittsburgh School of Medicine North Allegheny High School

Research Area

MedicineBioengineering

Biography

JoVE Journal Publications

Article Total : 2	Year
Publication title	2024
Publication title	2024

Other Publications

Article	Year
E3 ubiquitin ligase RNF126 affects bladder cancer progression through regulation of PTEN stability. Cell death & disease\| PubMed ID: 33664240	2021
The SUMOylation of zinc-fingers and homeoboxes 1 (ZHX1) by Ubc9 regulates its stability and transcriptional repression activity. Journal of cellular biochemistry\| PubMed ID: 23686912	2013
Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP. Virus research\| PubMed ID: 23702198	2013
VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability. Biochemical and biophysical research communications\| PubMed ID: 25732088	2015
Ionospheric correction based on ingestion of global ionospheric maps into the NeQuick 2 model. TheScientificWorldJournal\| PubMed ID: 25815369	2015
Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection. Scientific reports\| PubMed ID: 26481100	2015
Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway. Oncotarget\| PubMed ID: 27662662	2016
Capsaicin mediates caspases activation and induces apoptosis through P38 and JNK MAPK pathways in human renal carcinoma. BMC cancer\| PubMed ID: 27729033	2016
Capsaicin Suppresses Cell Proliferation, Induces Cell Cycle Arrest and ROS Production in Bladder Cancer Cells through FOXO3a-Mediated Pathways. Molecules (Basel, Switzerland)\| PubMed ID: 27775662	2016
Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway. Scientific reports\| PubMed ID: 27779188	2016
Downregulation of LAPTM5 suppresses cell proliferation and viability inducing cell cycle arrest at G0/G1 phase of bladder cancer cells. International journal of oncology\| PubMed ID: 27922670	2017
Downregulation of TRPM7 suppressed migration and invasion by regulating epithelial-mesenchymal transition in prostate cancer cells. Medical oncology (Northwood, London, England)\| PubMed ID: 28573641	2017
Silencing of induces dysregulation of cell cycle and ROS metabolism in bladder cancer cells via PPARγ-SIRT1 feedback loop. Journal of Cancer\| PubMed ID: 28819432	2017
Specific Expression of Interferon-γ Induced by Synergistic Activation Mediator-Derived Systems Activates Innate Immunity and Inhibits Tumorigenesis. Journal of microbiology and biotechnology\| PubMed ID: 28838224	2017
Identification and bioinformatics analysis of miRNAs associated with human muscle invasive bladder cancer. Molecular medicine reports\| PubMed ID: 28990088	2017
Overexpression of COL3A1 confers a poor prognosis in human bladder cancer identified by co-expression analysis. Oncotarget\| PubMed ID: 29050298	2017
Knockdown of Suppresses Bladder Cancer Cell Proliferation and Migration and Induces Cell Cycle Arrest and Antioxidant Response through FOXO3a-Mediated Pathways. BioMed research international\| PubMed ID: 29147649	2017
Co-expression network analysis identified six hub genes in association with progression and prognosis in human clear cell renal cell carcinoma (ccRCC). Genomics data\| PubMed ID: 29159069	2017
TM4SF1 regulates apoptosis, cell cycle and ROS metabolism via the PPARγ-SIRT1 feedback loop in human bladder cancer cells. Cancer letters\| PubMed ID: 29175458	2018
A novel correlation between ATP5A1 gene expression and progression of human clear cell renal cell carcinoma identified by co‑expression analysis. Oncology reports\| PubMed ID: 29207195	2018
Co-expression network analysis identified FCER1G in association with progression and prognosis in human clear cell renal cell carcinoma. International journal of biological sciences\| PubMed ID: 29209141	2017
FePt-Cys nanoparticles induce ROS-dependent cell toxicity, and enhance chemo-radiation sensitivity of NSCLC cells in vivo and in vitro. Cancer letters\| PubMed ID: 29331422	2018
CRISPR-Cas Targeting of Host Genes as an Antiviral Strategy. Viruses\| PubMed ID: 29337866	2018
Trichosanthin enhances sensitivity of non-small cell lung cancer (NSCLC) TRAIL-resistance cells. International journal of biological sciences\| PubMed ID: 29483839	2018
RNA interference-mediated depletion of TRPM8 enhances the efficacy of epirubicin chemotherapy in prostate cancer LNCaP and PC3 cells. Oncology letters\| PubMed ID: 29541177	2018
Identification of key genes and pathways in human clear cell renal cell carcinoma (ccRCC) by co-expression analysis. International journal of biological sciences\| PubMed ID: 29559845	2018
Genome scale screening identification of SaCas9/gRNAs for targeting HIV-1 provirus and suppression of HIV-1 infection. Virus research\| PubMed ID: 29625148	2018
Identification of Biomarkers Associated With Pathological Stage and Prognosis of Clear Cell Renal Cell Carcinoma by Co-expression Network Analysis. Frontiers in physiology\| PubMed ID: 29720944	2018
Bioinformatics and functional analyses of key genes and pathways in human clear cell renal cell carcinoma. Oncology letters\| PubMed ID: 29805645	2018
HIV-1 inhibition in cells with CXCR4 mutant genome created by CRISPR-Cas9 and piggyBac recombinant technologies. Scientific reports\| PubMed ID: 29872154	2018
β-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors. International journal of oncology\| PubMed ID: 30132512	2018
Co-expression Network Analysis of Biomarkers for Adrenocortical Carcinoma. Frontiers in genetics\| PubMed ID: 30158955	2018
Hepatitis B Virus Induces Autophagy to Promote its Replication by the Axis of miR-192-3p-XIAP Through NF kappa B Signaling. Hepatology (Baltimore, Md.)\| PubMed ID: 30180281	2019
SPOP suppresses prostate cancer through regulation of CYCLIN E1 stability. Cell death and differentiation\| PubMed ID: 30237511	2019
CIRBP is a novel oncogene in human bladder cancer inducing expression of HIF-1α. Cell death & disease\| PubMed ID: 30315244	2018
Identifying a Novel Biomarker of Clear Cell Renal Cell Carcinoma (ccRCC) Associated with Smoking by Co-Expression Network Analysis. Journal of Cancer\| PubMed ID: 30410595	2018
Prognostic value of a gene signature in clear cell renal cell carcinoma. Journal of cellular physiology\| PubMed ID: 30417359	2019
Fifteen hub genes associated with progression and prognosis of clear cell renal cell carcinoma identified by coexpression analysis. Journal of cellular physiology\| PubMed ID: 30417363	2019
miR-4324-RACGAP1-STAT3-ESR1 feedback loop inhibits proliferation and metastasis of bladder cancer. International journal of cancer\| PubMed ID: 30511377	2019
Identification of several cell cycle relevant genes highly correlated with the progression and prognosis of human bladder urothelial tumor. Journal of cellular physiology\| PubMed ID: 30618079	2019
Establishing a prediction model for prostate cancer bone metastasis. International journal of biological sciences\| PubMed ID: 30662360	2019
Long non-coding RNA SNHG6 is upregulated in prostate cancer and predicts poor prognosis. Molecular biology reports\| PubMed ID: 30911973	2019
PPARγ inhibition regulates the cell cycle, proliferation and motility of bladder cancer cells. Journal of cellular and molecular medicine\| PubMed ID: 30912275	2019
Identification of a three-miRNA signature as a novel potential prognostic biomarker in patients with clear cell renal cell carcinoma. Journal of cellular biochemistry\| PubMed ID: 30957284	2019
Flux melting of metal-organic frameworks. Chemical science\| PubMed ID: 30996951	2019
Neuroanatomical Changes Underlying Vertical HIV Infection in Adolescents. Frontiers in immunology\| PubMed ID: 31110499	2019
Re: Perioperative Oral Nutrition Supplementation Reduces Prevalence of Sarcopenia following Radical Cystectomy: Results of a Prospective Randomized Controlled Trial. The Journal of urology\| PubMed ID: 31166840	2019
FePt/GO Nanosheets Suppress Proliferation, Enhance Radiosensitization and Induce Autophagy of Human Non-Small Cell Lung Cancer Cells. International journal of biological sciences\| PubMed ID: 31182920	2019
Re: Stacy Loeb, Jacob Taylor, Mohit Butaney, et al. Twitter-based Prostate Cancer Journal Club (#ProstateJC) Promotes Multidisciplinary Global Scientific Discussion and Research Disseminatio... European urology\| PubMed ID: 31229325	2020
PPARα gene is a diagnostic and prognostic biomarker in clear cell renal cell carcinoma by integrated bioinformatics analysis. Journal of Cancer\| PubMed ID: 31258735	2019
Co-expression network analysis identified candidate biomarkers in association with progression and prognosis of breast cancer. Journal of cancer research and clinical oncology\| PubMed ID: 31280346	2019
Re: Brandon A. Mahal, Mohammed Alshalalfa, Daniel E. Spratt, et al. Prostate Cancer Genomic-risk Differences Between African-American and White Men Across Gleason Scores. Eur Urol 2019;75:10... European urology\| PubMed ID: 31326220	2020
Fatty acid oxidation inhibitor etomoxir suppresses tumor progression and induces cell cycle arrest via PPARγ-mediated pathway in bladder cancer. Clinical science (London, England : 1979)\| PubMed ID: 31358595	2019
Re: Kimmo Kettunen, Peter J. Boström, Tarja Lamminen, et al. Personalized Drug Sensitivity Screening for Bladder Cancer Using Conditionally Reprogrammed Patient-derived Cells. Eur Urol 2019;... European urology\| PubMed ID: 31420251	2019
Identification of 9 key genes and small molecule drugs in clear cell renal cell carcinoma. Aging\| PubMed ID: 31422942	2019
PPWD1 is associated with the occurrence of postmenopausal osteoporosis as determined by weighted gene co‑expression network analysis. Molecular medicine reports\| PubMed ID: 31432133	2019
EFEMP2 suppresses epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in human bladder cancer. International journal of biological sciences\| PubMed ID: 31592144	2019
ACAT1 and Metabolism-Related Pathways Are Essential for the Progression of Clear Cell Renal Cell Carcinoma (ccRCC), as Determined by Co-expression Network Analysis. Frontiers in oncology\| PubMed ID: 31649873	2019
Novel Biomarkers Associated With Progression and Prognosis of Bladder Cancer Identified by Co-expression Analysis. Frontiers in oncology\| PubMed ID: 31681575	2019
LPS impairs steroidogenesis and ROS metabolism and induces PPAR transcriptional activity to disturb estrogen/androgen receptor expression in testicular cells. Molecular biology reports\| PubMed ID: 31741264	2020
Establishing the prediction models for recurrence and progression of T1G3 bladder urothelial carcinoma. Journal of Cancer\| PubMed ID: 31762799	2019
Inhibition of MELK produces potential anti-tumour effects in bladder cancer by inducing G1/S cell cycle arrest via the ATM/CHK2/p53 pathway. Journal of cellular and molecular medicine\| PubMed ID: 31821699	2020
An outcome model for human bladder cancer: A comprehensive study based on weighted gene co-expression network analysis. Journal of cellular and molecular medicine\| PubMed ID: 31883309	2020
Green Gas-Mediated Cross-Linking Generates Biomolecular Hydrogels with Enhanced Strength and Excellent Hemostasis for Wound Healing. ACS applied materials & interfaces\| PubMed ID: 32163261	2020
Strengthened Monitoring of H5 Avian Influenza Viruses in External Environment in Hubei, 2018. Current medical science\| PubMed ID: 32166666	2020
Clinical Characteristics of Refractory Coronavirus Disease 2019 in Wuhan, China. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 32173725	2021
Post-discharge surveillance and positive virus detection in two medical staff recovered from coronavirus disease 2019 (COVID-19), China, January to February 2020. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin\| PubMed ID: 32183934	2020
Pedigree analysis of a POLD1 germline mutation in urothelial carcinoma shows a close association between different mutation burdens and overall survival. Cellular & molecular immunology\| PubMed ID: 32265515	2021
Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Renal Failure Patients: A Potential Covert Source of Infection. European urology\| PubMed ID: 32279905	2020
The role and function of PPARγ in bladder cancer. Journal of Cancer\| PubMed ID: 32328200	2020
High Flexible and Broad Antibacterial Nanodressing Induces Complete Skin Repair with Angiogenic and Follicle Regeneration. Advanced healthcare materials\| PubMed ID: 32378346	2020
Reply to Peng He, Xiaohui Wang, and Hao Li's Letter to the Editor re: Yu Xiao, Kaiyu Qian, Yongwen Luo, et al. Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Renal Failure Pati... European urology\| PubMed ID: 32405138	2020
Comprehensive genomic profiling of urothelial carcinoma cell lines reveals hidden research bias and caveats. Clinical and translational medicine\| PubMed ID: 32508016	2020
Conditional reprogramming: Modeling urological cancer and translation to clinics. Clinical and translational medicine\| PubMed ID: 32508060	2020
MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair. International journal of biological sciences\| PubMed ID: 32549761	2020
BORA regulates cell proliferation and migration in bladder cancer. Cancer cell international\| PubMed ID: 32655322	2020
WFDC2 suppresses prostate cancer metastasis by modulating EGFR signaling inactivation. Cell death & disease\| PubMed ID: 32678075	2020
Tumor mutational burden related classifier is predictive of response to PD-L1 blockade in locally advanced and metastatic urothelial carcinoma. International immunopharmacology\| PubMed ID: 32738594	2020
Emergency response to the explosive growth of health care wastes during COVID-19 pandemic in Wuhan, China. Resources, conservation, and recycling\| PubMed ID: 32834492	2021
Immune-related signature predicts the prognosis and immunotherapy benefit in bladder cancer. Cancer medicine\| PubMed ID: 32841548	2020
TRPM8 Inhibition Regulates the Proliferation, Migration and ROS Metabolism of Bladder Cancer Cells. OncoTargets and therapy\| PubMed ID: 32943886	2020
A novel germline EGFR variant p.R831H causes predisposition to familial CDK12-mutant prostate cancer with tandem duplicator phenotype. Oncogene\| PubMed ID: 32978518	2020
Identification of a prognostic gene signature based on an immunogenomic landscape analysis of bladder cancer. Journal of cellular and molecular medicine\| PubMed ID: 33048468	2020
Suppressive effects of plumbagin on the growth of human bladder cancer cells via PI3K/AKT/mTOR signaling pathways and EMT. Cancer cell international\| PubMed ID: 33117085	2020
Epigenetic signature predicts overall survival clear cell renal cell carcinoma. Cancer cell international\| PubMed ID: 33292239	2020
PfAgo-based detection of SARS-CoV-2. Biosensors & bioelectronics\| PubMed ID: 33429204	2021
KNSTRN promotes tumorigenesis and gemcitabine resistance by activating AKT in bladder cancer. Oncogene\| PubMed ID: 33452459	2021
Mutational burden and chromosomal aneuploidy synergistically predict survival from radiotherapy in non-small cell lung cancer. Communications biology\| PubMed ID: 33514859	2021
The immune-related biomarker TEK inhibits the development of clear cell renal cell carcinoma (ccRCC) by regulating AKT phosphorylation. Cancer cell international\| PubMed ID: 33602230	2021
The inhibitory effect of melatonin on human prostate cancer. Cell communication and signaling : CCS\| PubMed ID: 33722247	2021
Generation of two induced pluripotent stem cell lines from blood cells of a prostate cancer patient carrying germline mutation in CHEK2. Stem cell research\| PubMed ID: 33780728	2021
The inhibitory effect of silencing CDCA3 on migration and proliferation in bladder urothelial carcinoma. Cancer cell international\| PubMed ID: 33980246	2021
MUC3A induces PD-L1 and reduces tyrosine kinase inhibitors effects in EGFR-mutant non-small cell lung cancer. International journal of biological sciences\| PubMed ID: 33994852	2021
(S,R)3-(4-Hydroxyphenyl)-4,5-Dihydro-5-Isoxazole Acetic Acid Methyl Ester Inhibits Epithelial-to-Mesenchymal Transition Through TGF-β/Smad4 Axis in Nasopharyngeal Carcinoma. Anti-cancer agents in medicinal chemistry\| PubMed ID: 34229595	2022
MUC3A promotes non-small cell lung cancer progression via activating the NFκB pathway and attenuates radiosensitivity. International journal of biological sciences\| PubMed ID: 34326691	2021
Ginkgolic Acid Suppresses Nasopharyngeal Carcinoma Growth by Inducing Apoptosis and Inhibiting Signaling. Journal of medicinal food\| PubMed ID: 34382859	2021
HIF-1α promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19. Signal transduction and targeted therapy\| PubMed ID: 34408131	2021
The cholesterol esterification inhibitor avasimibe suppresses tumour proliferation and metastasis via the E2F-1 signalling pathway in prostate cancer. Cancer cell international\| PubMed ID: 34461908	2021
PRR11 promotes ccRCC tumorigenesis by regulating E2F1 stability. JCI insight\| PubMed ID: 34499617	2021
A combination of laparoscopic approach and ERAS pathway optimizes outcomes and cost for adrenalectomy. Updates in surgery\| PubMed ID: 34635985	2022
Improving Ponzi Scheme Contract Detection Using Multi-Channel TextCNN and Transformer. Sensors (Basel, Switzerland)\| PubMed ID: 34640737	2021
E3 ubiquitin ligase ring finger protein 5 protects against hepatic ischemia reperfusion injury by mediating phosphoglycerate mutase family member 5 ubiquitination. Hepatology (Baltimore, Md.)\| PubMed ID: 34735734	2022
Corrigendum to "TM4SF1 regulates apoptosis, cell cycle and ROS metabolism via the PPARγ-SIRT1 feedback loop in human bladder cancer cells" [Cancer Lett. 414 (1 February 2018) 278-293]. Cancer letters\| PubMed ID: 34785090	2022
Development and Validation of a Six-Gene Prognostic Signature for Bladder Cancer. Frontiers in genetics\| PubMed ID: 34938313	2021
Editorial: The Role of Epithelial-Mesenchymal Transition-Related Non-Coding RNAs in Cancer. Frontiers in molecular biosciences\| PubMed ID: 35127832	2022
The role of amygdala neuropsin/serpinb6 pathway in the regulation of gastric hypersensitivity and anxiety by electroacupuncture. Journal of digestive diseases\| PubMed ID: 35179294	2022
Erratum: EFEMP2 suppresses epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in human bladder cancer: Erratum. International journal of biological sciences\| PubMed ID: 35813466	2022
Non-invasive diagnosis and surveillance of bladder cancer with driver and passenger DNA methylation in a prospective cohort study. Clinical and translational medicine\| PubMed ID: 35968916	2022
MYBL2 promotes proliferation and metastasis of bladder cancer through transactivation of CDCA3. Oncogene\| PubMed ID: 36071275	2022
Correction to: Downregulation of TRPM7 suppressed migration and invasion by regulating epithelial-mesenchymal transition in prostate cancer cells. Medical oncology (Northwood, London, England)\| PubMed ID: 36071297	2022
Ultrasensitive tumour-agnostic non-invasive detection of colorectal cancer recurrence using ctDNA methylation. Clinical and translational medicine\| PubMed ID: 36103400	2022
A nomogram for predicting overall survival rate in patients with brain metastatic non-small cell lung cancer. Medicine\| PubMed ID: 36197226	2022
Prognostic nomogram for female patients suffering from non-metastatic Her2 positive breast cancer: A SEER-based study. Medicine\| PubMed ID: 36221419	2022
Correction: Qian et al. Capsaicin Suppresses Cell Proliferation, Induces Cell Cycle Arrest and ROS Production in Bladder Cancer Cells through FOXO3a-Mediated Pathways. 2016, , 1406. Molecules (Basel, Switzerland)\| PubMed ID: 36235311	2022
Editorial: Molecular biomarkers and imaging markers in the prediction, diagnosis, and prognosis of bladder cancer. Frontiers in cell and developmental biology\| PubMed ID: 36313549	2022
Erratum: MUC3A promotes non-small cell lung cancer progression via activating the NFκB pathway and attenuates radiosensitivity. International journal of biological sciences\| PubMed ID: 36439877	2022
An unusual case report of porokeratosis ptychotropica on the buttocks. Medicine\| PubMed ID: 36451470	2022
Genetically supported causality between benign prostate hyperplasia and urinary bladder neoplasms: A mendelian randomization study. Frontiers in genetics\| PubMed ID: 36468030	2022
Ti-MOF single-crystals featuring an intracrystal macro-microporous hierarchy for catalytic oxidative desulfurization. Chemical communications (Cambridge, England)\| PubMed ID: 36722396	2023
Treatment of paradoxical eczematous eruption in psoriasis treated with secukinumab: A case report. Medicine\| PubMed ID: 36820537	2023
and Serve as Prognostic Biomarkers Associated with an Inflamed Immunosuppressive Tumor Microenvironment in Hepatocellular Carcinoma. International journal of molecular sciences\| PubMed ID: 36834567	2023
Genetic characterization of human adenoviruses in patients using metagenomic next-generation sequencing in Hubei, China, from 2018 to 2019. Frontiers in microbiology\| PubMed ID: 37007506	2023
Melatonin inhibits bladder tumorigenesis by suppressing PPARγ/ENO1-mediated glycolysis. Cell death & disease\| PubMed ID: 37024456	2023
Histone methyltransferase SETD2: An epigenetic driver in clear cell renal cell carcinoma. Frontiers in oncology\| PubMed ID: 37025591	2023
A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA. Genome biology\| PubMed ID: 37095549	2023
DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC. Nature communications\| PubMed ID: 37105989	2023
TLR7 Agonists Modulate the Activation of Human Conjunctival Epithelial Cells Induced by IL-1β via the ERK1/2 Signaling Pathway. Inflammation\| PubMed ID: 37154978	2023
Pectolinarigenin inhibits bladder urothelial carcinoma cell proliferation by regulating DNA damage/autophagy pathways. Cell death discovery\| PubMed ID: 37393350	2023
Direct blue 53, a biological dye, inhibits SARS-CoV-2 infection by blocking ACE2 and spike interaction in vitro and in vivo. Virology\| PubMed ID: 37531695	2023
Anti-melanoma differentiation-associated gene 5 and anti-Ro52 antibody-dual positive dermatomyositis accompanied by rapidly lung disease: Three case reports. World journal of clinical cases\| PubMed ID: 37637698	2023
PCG-net: feature adaptive deep learning for automated head and neck organs-at-risk segmentation. Frontiers in oncology\| PubMed ID: 37927463	2023
TRAIP suppresses bladder cancer progression by catalyzing K48-linked polyubiquitination of MYC. Oncogene\| PubMed ID: 38123820	2023
Acyl-coenzyme A: cholesterol acyltransferase inhibitor avasimibe suppresses tumorigenesis and induces G1-phase cell-cycle arrest by activating PPARγ signaling pathway in bladder cancer. Journal of Cancer\| PubMed ID: 38169575	2024
DLGAP5 triggers proliferation and metastasis of bladder cancer by stabilizing E2F1 via USP11. Oncogene\| PubMed ID: 38182895	2024
USP43 stabilizes c-Myc to promote glycolysis and metastasis in bladder cancer. Cell death & disease\| PubMed ID: 38218970	2024