School of Pharmacy,
Key Laboratory of Molecular Pharmacology and Drug Evaluation,
Ministry of Education,
Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong,
School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong
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Effects of escin on acute inflammation and the immune system in mice.
Pharmacological reports : PR , 2009 | Pubmed ID: 19815952
Reduced glutathione attenuates liver injury induced by methyl parathion in rats.
Toxicology mechanisms and methods Feb, 2010 | Pubmed ID: 20100039
Study on the structure-function relationship of 20(S)-panaxadiol and its epimeric derivatives in myocardial injury induced by isoproterenol.
Fitoterapia Oct, 2010 | Pubmed ID: 20398743
Escin attenuates cognitive deficits and hippocampal injury after transient global cerebral ischemia in mice via regulating certain inflammatory genes.
Neurochemistry international Sep, 2010 | Pubmed ID: 20466027
Protective effects of Danshensu on liver injury induced by omethoate in rats.
Toxicology mechanisms and methods Oct, 2010 | Pubmed ID: 20843270
Escin exerts synergistic anti-inflammatory effects with low doses of glucocorticoids in vivo and in vitro.
Phytomedicine : international journal of phytotherapy and phytopharmacology Feb, 2011 | Pubmed ID: 20850956
Escin attenuates acute lung injury induced by endotoxin in mice.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Jan, 2011 | Pubmed ID: 21040784
Protective effect of sodium aescinate on lung injury induced by methyl parathion.
Human & experimental toxicology Oct, 2011 | Pubmed ID: 21177729
The Role of P-Glycoprotein in Transport of Danshensu across the Blood-Brain Barrier.
Evidence-based complementary and alternative medicine : eCAM , 2011 | Pubmed ID: 21318104
Escin attenuates cerebral edema induced by acute omethoate poisoning.
Toxicology mechanisms and methods Jun, 2011 | Pubmed ID: 21417632
The potent anti-inflammatory agent escin does not increase corticosterone secretion and immune cell apoptosis in mice.
Fitoterapia Sep, 2011 | Pubmed ID: 21596110
Protective effect of aescin from the seeds of Aesculus hippocastanum on liver injury induced by endotoxin in mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology Nov, 2011 | Pubmed ID: 21802269
Down-regulation of P-glycoprotein expression contributes to an increase in Danshensu accumulation in the cerebral ischemia/reperfusion brain.
Molecular medicine reports Mar, 2012 | Pubmed ID: 22134431
Steady and fluctuant methods of inhibition of acetylcholinesterase differentially regulate neurotrophic factors in the hippocampus of juvenile mice.
Experimental and therapeutic medicine Feb, 2012 | Pubmed ID: 22969880
Potent anti-inflammatory agent escin does not affect the healing of tibia fracture and abdominal wound in an animal model.
Experimental and therapeutic medicine Apr, 2012 | Pubmed ID: 22969961
Sodium aescinate ameliorates liver injury induced by methyl parathion in rats.
Experimental and therapeutic medicine May, 2012 | Pubmed ID: 22969975
Anti-inflammatory activity of Yanshu spraying agent in animal models.
Experimental and therapeutic medicine Jan, 2013 | Pubmed ID: 23251244
Hypersensitivity reaction studies of a polyethoxylated castor oil-free, liposome-based alternative paclitaxel formulation.
Molecular medicine reports Mar, 2013 | Pubmed ID: 23291923
The effects of huperzine A on gastrointestinal acetylcholinesterase activity and motility after single and multiple dosing in mice.
Experimental and therapeutic medicine Mar, 2013 | Pubmed ID: 23403922
Neuroprotective effect of hydroxysafflor yellow A on 6-hydroxydopamine-induced Parkinson's disease in rats.
European journal of pharmacology Aug, 2013 | Pubmed ID: 23791614
Ginsenoside Rg1 exerts synergistic anti-inflammatory effects with low doses of glucocorticoids in vitro.
Fitoterapia Dec, 2013 | Pubmed ID: 24035860
Inhibition of sPLA₂-IIA prevents LPS-induced neuroinflammation by suppressing ERK1/2-cPLA₂α pathway in mice cerebral cortex.
PloS one , 2013 | Pubmed ID: 24130900
Effects of the coadministration of Huatuo Zaizao pills and aspirin on hemorrheology and blood coagulation in rabbits.
Biomedical reports May, 2013 | Pubmed ID: 24648968
A novel approach to medical countermeasures against organophosphorus compound toxicity.
Biomedical reports Nov, 2013 | Pubmed ID: 24649050
Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects.
Experimental and therapeutic medicine Apr, 2014 | Pubmed ID: 24669264
Protective effects of escin against indomethacin-induced gastric ulcer in mice.
Toxicology mechanisms and methods Dec, 2014 | Pubmed ID: 25137224
A potential target for the treatment of Parkinson's disease: effect of lateral habenula lesions.
Parkinsonism & related disorders Nov, 2014 | Pubmed ID: 25219971
Ferulic acid ameliorates nerve injury induced by cerebral ischemia in rats.
Experimental and therapeutic medicine Mar, 2015 | Pubmed ID: 25667662
Coadministration of hydroxysafflor yellow A with levodopa attenuates the dyskinesia.
Physiology & behavior Aug, 2015 | Pubmed ID: 25914172
Oral Administration of Escin Inhibits Acute Inflammation and Reduces Intestinal Mucosal Injury in Animal Models.
Evidence-based complementary and alternative medicine : eCAM , 2015 | Pubmed ID: 26199634
Neurological function following cerebral ischemia/reperfusion is improved by the Ruyi Zhenbao pill in a rats.
Biomedical reports Feb, 2016 | Pubmed ID: 26893831
Evaluation of the Antidepressant Activity, Hepatotoxicity and Blood Brain Barrier Permeability of Methyl Genipin.
Molecules (Basel, Switzerland) Jul, 2016 | Pubmed ID: 27438811
Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment Ameliorate Acetaminophen-Induced Liver Injury in Mice via Central Cholinergic System Regulation.
The Journal of pharmacology and experimental therapeutics Nov, 2016 | Pubmed ID: 27535978
Huatuo Zaizao pill promotes functional recovery and neurogenesis after cerebral ischemia-reperfusion in rats.
BMC complementary and alternative medicine Jan, 2017 | Pubmed ID: 28056920
Hydroxysafflor Yellow A Improves Motor Dysfunction in the Rotenone-Induced Mice Model of Parkinson's Disease.
Neurochemical research May, 2017 | Pubmed ID: 28097465
Osteogenic potency of dedifferentiated fat cells isolated from elderly people with osteoporosis.
Experimental and therapeutic medicine Jul, 2017 | Pubmed ID: 28672891
Ginsenoside Rg1 attenuates adjuvant-induced arthritis in rats via modulation of PPAR-γ/NF-κB signal pathway.
Oncotarget Aug, 2017 | Pubmed ID: 28903427
Activation of dopamine D1 receptor decreased NLRP3-mediated inflammation in intracerebral hemorrhage mice.
Journal of neuroinflammation Jan, 2018 | Pubmed ID: 29301581
Hydroxysafflor Yellow A Attenuates Lipopolysaccharide-Induced Neurotoxicity and Neuroinflammation in Primary Mesencephalic Cultures.
Molecules (Basel, Switzerland) May, 2018 | Pubmed ID: 29783643
Neuroprotective effects of Danshensu in Parkinson's disease mouse model induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Behavioural pharmacology Feb, 2019 | Pubmed ID: 29847337
Effects of rotigotine and rotigotine extended-release microsphere therapy on myocardial ischemic injury in mice.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Jun, 2019 | Pubmed ID: 30959104
Network Pharmacology Based Research on the Combination Mechanism Between Escin and Low Dose Glucocorticoids in Anti-rheumatoid Arthritis.
Frontiers in pharmacology , 2019 | Pubmed ID: 30967782
Neuroprotective effects of Danshensu on rotenone-induced Parkinson's disease models in vitro and in vivo.
BMC complementary medicine and therapies Jan, 2020 | Pubmed ID: 32020857
Rosmarinic acid protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity in zebrafish embryos.
Toxicology in vitro : an international journal published in association with BIBRA Jun, 2020 | Pubmed ID: 32147576
Severe Acute Lung Injury Related to COVID-19 Infection: A Review and the Possible Role for Escin.
Journal of clinical pharmacology Jul, 2020 | Pubmed ID: 32441805
Inhibition of notch enhances the anti-atherosclerotic effects of LXR agonists while reducing fatty liver development in ApoE-deficient mice.
Toxicology and applied pharmacology Nov, 2020 | Pubmed ID: 32853627
Antinociceptive effects of rotigotine-loaded microspheres and its synergistic interactions with analgesics in inflammatory pain in rats.
European journal of pharmacology Jan, 2021 | Pubmed ID: 33160937
The Effect of Rotigotine Extended-Release Microspheres Alone or With Celecoxib on the Inflammatory Pain.
Frontiers in pharmacology , 2020 | Pubmed ID: 33192533
Escin ameliorates the impairments of neurological function and blood brain barrier by inhibiting systemic inflammation in intracerebral hemorrhagic mice.
Experimental neurology Mar, 2021 | Pubmed ID: 33309746
Glucocorticoid-Like Activity of Escin: A New Mechanism for an Old Drug.
Drug design, development and therapy , 2021 | Pubmed ID: 33658760
Is it Possible to Estimate the Bioequivalence between Parenteral and Enteral Formulations of Escin?
Current reviews in clinical and experimental pharmacology , 2022 | Pubmed ID: 33687899
Lipopolysaccharide/D-galactosamine-induced acute liver injury could be attenuated by dopamine receptor agonist rotigotine via regulating NF-κB signaling pathway.
International immunopharmacology Jul, 2021 | Pubmed ID: 34162160
Ginsenoside Rg2 Ameliorates Brain Injury After Intracerebral Hemorrhage in a Rat Model of Preeclampsia.
Reproductive sciences (Thousand Oaks, Calif.) Dec, 2021 | Pubmed ID: 34270001
Ginsenoside Rg3 exerts a neuroprotective effect in rotenone-induced Parkinson's disease mice via its anti-oxidative properties.
European journal of pharmacology Oct, 2021 | Pubmed ID: 34391769
Rotigotine-loaded microspheres exerts the antinociceptive effect via central dopaminergic system.
European journal of pharmacology Nov, 2021 | Pubmed ID: 34464604
Dopamine receptor agonist rotigotine-loaded microspheres ameliorates sexual function deteriorated by fluoxetine in depression rats.
ASN neuro , 2021 | Pubmed ID: 34724850
Dopamine, a co-regulatory component, bridges the central nervous system and the immune system.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Jan, 2022 | Pubmed ID: 34847478
The Use of Herbal Medicines for the Prevention of Glucocorticoid-Induced Osteoporosis.
Frontiers in endocrinology , 2021 | Pubmed ID: 34867788
Continuous Activation of Dopamine Receptors Alleviates LPS-Induced Liver Injury in Mice via β-arrestin2 Dependent Akt/NF-κB Pathway.
Frontiers in pharmacology , 2022 | Pubmed ID: 35359858
Meldonium Ameliorates Hypoxia-Induced Lung Injury and Oxidative Stress by Regulating Platelet-Type Phosphofructokinase-Mediated Glycolysis.
Frontiers in pharmacology , 2022 | Pubmed ID: 35450040
The etiology of poststroke-depression: a hypothesis involving HPA axis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Jul, 2022 | Pubmed ID: 35643064
Integrated systematic pharmacology analysis and experimental validation to reveal the mechanism of action of Semen aesculi on inflammatory bowel diseases.
Journal of ethnopharmacology Nov, 2022 | Pubmed ID: 35985613
Rosmarinic Acid Attenuates Rotenone-Induced Neurotoxicity in SH-SY5Y Parkinson's Disease Cell Model through Abl Inhibition.
Nutrients Aug, 2022 | Pubmed ID: 36079767
Administration of Huperzine A microspheres ameliorates myocardial ischemic injury via α7nAChR-dependent JAK2/STAT3 signaling pathway.
European journal of pharmacology Feb, 2023 | Pubmed ID: 36563953
Escin alleviates stress-induced intestinal dysfunction to protect brain injury by regulating the gut-brain axis in ischemic stroke rats.
International immunopharmacology Feb, 2023 | Pubmed ID: 36608442
The effect of triple reuptake inhibitor toludesvenlafaxine on neurological function in cerebral ischemic rats.
Frontiers in pharmacology , 2023 | Pubmed ID: 37153779
Effects of natural products on skin inflammation caused by abnormal hormones secreted by the adrenal gland.
Frontiers in pharmacology , 2023 | Pubmed ID: 37205913
LAR Downregulation Protects the Astrocytic U251 and Cocultured SH-SY5Y Cells in a Rotenone-Induced Parkinson's Disease Cell Model.
International journal of molecular sciences Jul, 2023 | Pubmed ID: 37446291
Escin avoids hemorrhagic transformation in ischemic stroke by protecting BBB through the AMPK/Cav-1/MMP-9 pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology Nov, 2023 | Pubmed ID: 37716034
Antinociceptive effects of carbidopa levodopa on normal rats and Parkinson's disease mice.
Pakistan journal of pharmaceutical sciences Sep, 2023 | Pubmed ID: 37869925
Biofluid biomarkers for Alzheimer's disease.
Frontiers in aging neuroscience , 2024 | Pubmed ID: 38659704
Zhang Jiren1,
Jia Xue2,
Sun Yufei2,
Li Huiwen2,
Yang Jian1,
Qi Shilei1,
Zhao Dongman1,
Xie Lei1,
Jia Mingming1,
Wang Tian2,
Zhang Pinyuan1
1Department of Neurosurgery, The Third Hospital of Hebei Medical University,
2School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University
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