Clayton Cuddington

William G. Lowrie Department of Chemical and Biomolecular Engineering,
College of Engineering,
William G. Lowrie Department of Chemical and Biomolecular Engineering, College of Engineering

The Ohio State University

BIOGRAPHY

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PUBLICATIONS

Controlled Polymerization and Ultrafiltration Increase the Consistency of Polymerized Hemoglobin for Use as an Oxygen Carrier.

Bioconjugate chemistry 03, 2020 | Pubmed ID: 31868349

Next-generation polymerized human hemoglobins in hepatic bioreactor simulations.

Biotechnology progress May, 2020 | Pubmed ID: 31922354

Injectable biodegradable bi-layered capsule for sustained delivery of bevacizumab in treating wet age-related macular degeneration.

Journal of controlled release : official journal of the Controlled Release Society 04, 2020 | Pubmed ID: 31981659

Targeted Myoglobin Delivery as a Strategy for Enhancing the Sensitivity of Hypoxic Cancer Cells to Radiation.

iScience Jun, 2020 | Pubmed ID: 32464594

Comprehensive characterization of tense and relaxed quaternary state glutaraldehyde polymerized bovine hemoglobin as a function of cross-link density.

Biotechnology and bioengineering 08, 2020 | Pubmed ID: 32472694

Resuscitation from hemorrhagic shock after traumatic brain injury with polymerized hemoglobin.

Scientific reports 01, 2021 | Pubmed ID: 33510204

Biophysical properties of tense quaternary state polymerized human hemoglobins bracketed between 500 kDa and 0.2 μm in size.

Biotechnology progress Oct, 2021 | Pubmed ID: 34626100

Scalable production and complete biophysical characterization of poly(ethylene glycol) surface conjugated liposome encapsulated hemoglobin (PEG-LEH).

PloS one , 2022 | Pubmed ID: 35802716

Pilot scale production and characterization of next generation high molecular weight and tense quaternary state polymerized human hemoglobin.

Biotechnology and bioengineering Dec, 2022 | Pubmed ID: 36120842

Safety and efficacy of human polymerized hemoglobin on guinea pig resuscitation from hemorrhagic shock.

Scientific reports Nov, 2022 | Pubmed ID: 36443351

Polymerized human hemoglobin with low and high oxygen affinity in trauma models.

Translational research : the journal of laboratory and clinical medicine Oct, 2023 | Pubmed ID: 37268039

Polymerized Human Hemoglobin-Based Oxygen Carrier Preserves Lung Allograft Function During Normothermic Ex Vivo Lung Perfusion.

ASAIO journal (American Society for Artificial Internal Organs : 1992) May, 2024 | Pubmed ID: 38266069

Novel high molecular weight polymerized hemoglobin in a non-obese model of cardiovascular and metabolic dysfunction.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie May, 2024 | Pubmed ID: 38815289

INSTITUTIONS

The Ohio State University

JOVE ARTICLES

Exploring Alternative Perfusion Solutions Using Next-Generation Polymerized Hemoglobin-Based Oxygen Carriers in a Model of Rat Ex Vivo Lung Perfusion

Doug A. Gouchoe^*,1,2,

Yong Gyu Lee^*,1,2,

Alisyn Greenfield³,

Clayton Cuddington³,

Jung-Lye Kim^1,2,

Sylvester M. Black¹,

Andre F. Palmer³,

Bryan A. Whitson^1,2

¹COPPER Laboratory, Department of Surgery, The Ohio State University Wexner Medical Center,

²Division of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center,

³William G. Lowrie Department of Chemical and Biomolecular Engineering, College of Engineering, The Ohio State University

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Clayton Cuddington

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}William G. Lowrie Department of Chemical and Biomolecular Engineering,College of Engineering,William G. Lowrie Department of Chemical and Biomolecular Engineering, College of Engineering

The Ohio State University

Exploring Alternative Perfusion Solutions Using Next-Generation Polymerized Hemoglobin-Based Oxygen Carriers in a Model of Rat Ex Vivo Lung Perfusion

William G. Lowrie Department of Chemical and Biomolecular Engineering,
College of Engineering,
William G. Lowrie Department of Chemical and Biomolecular Engineering, College of Engineering