Walter Born

Functional interaction of G protein-coupled receptors of the adrenomedullin peptide family with accessory receptor-activity-modifying proteins (RAMP).

International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors.

The transmembrane domain of receptor-activity-modifying protein 1 is essential for the functional expression of a calcitonin gene-related peptide receptor.

Paracrine/autocrine function of adrenomedullin in peripheral nerves of rats.

The extreme N-terminus of the calcitonin-like receptor contributes to the selective interaction with adrenomedullin or calcitonin gene-related peptide.

Adrenomedullin selectivity of calcitonin-like receptor/receptor activity modifying proteins.

Three receptor-activity-modifying proteins define calcitonin gene-related peptide or adrenomedullin selectivity of the mouse calcitonin-like receptor in COS-7 cells.

The function of conserved cysteine residues in the extracellular domain of human receptor-activity-modifying protein.

Selective inactivation of adrenomedullin over calcitonin gene-related peptide receptor function by the deletion of amino acids 14-20 of the mouse calcitonin-like receptor.

Aspartate(69) of the calcitonin-like receptor is required for its functional expression together with receptor-activity-modifying proteins 1 and -2.

Introductory notes. Old and new paradigms in the field of the calcitonin family of peptides.

Biological importance of the peptides of the calcitonin family as revealed by disruption and transfer of corresponding genes.

Stimulation of neurite outgrowth in a human nerve scaffold designed for peripheral nerve reconstruction.

Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome.

The N-terminal extracellular domain 23-60 of the calcitonin receptor-like receptor in chimeras with the parathyroid hormone receptor mediates association with receptor activity-modifying protein 1.

Self-assembly of sensory neurons into ganglia-like microtissues.

Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells.

Design of custom-shaped vascularized tissues using microtissue spheroids as minimal building units.

Taurolidine: a novel anti-neoplastic agent induces apoptosis of osteosarcoma cell lines.

Interaction of receptor-activity-modifying protein1 with tubulin.

Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma.

Calcitonin gene-related peptide-evoked sustained tachycardia in calcitonin receptor-like receptor transgenic mice is mediated by sympathetic activity.

Cathepsins and osteosarcoma: Expression analysis identifies cathepsin K as an indicator of metastasis.

Cytotoxic effects of curcumin on osteosarcoma cell lines.

Altered morphology, nuclear stability and adhesion of highly metastatic derivatives of osteoblast-like SAOS-2 osteosarcoma cells.

Upregulation of alpha-skeletal muscle actin and myosin heavy polypeptide gene products in degenerating rotator cuff muscles.

Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion.

Identification of potential chemoresistance genes in osteosarcoma.

Adipogenic and myogenic gene expression in rotator cuff muscle of the sheep after tendon tear.

Protection of angiotensin II-induced vascular hypertrophy in vascular smooth muscle-targeted receptor activity-modifying protein 2 transgenic mice.

LacZ transgene expression in the subcutaneous Dunn/LM8 osteosarcoma mouse model allows for the identification of micrometastasis.

Antimetastatic activity of honokiol in osteosarcoma.

Cyr61 expression in Osteosarcoma indicates poor prognosis and promotes intratibial growth and lung metastasis in mice.

The antineoplastic antibiotic taurolidine promotes lung and liver metastasis in two syngeneic osteosarcoma mouse models and exhibits severe liver toxicity.

mTHPC-mediated photodynamic therapy is effective in the metastatic human 143B osteosarcoma cells.

Taurolidine: Mode of administration in mouse tumor models.

CD44 enhances tumor formation and lung metastasis in experimental osteosarcoma and is an additional predictor for poor patient outcome.

Matrix Metalloproteinase 1 promotes tumor formation and lung metastasis in an intratibial injection osteosarcoma mouse model.

Genes regulated in metastatic osteosarcoma: evaluation by microarray analysis in four human and two mouse cell line systems.

A new method for repeated drug infusion into the femoral artery of mice.

Caprin-1, a novel Cyr61-interacting protein, promotes osteosarcoma tumor growth and lung metastasis in mice.

Evaluation of quercetin as a potential drug in osteosarcoma treatment.

Silencing of CD44 gene expression in human 143-B osteosarcoma cells promotes metastasis of intratibial tumors in SCID mice.

Characterization of different osteosarcoma phenotypes by PET imaging in preclinical animal models.

Expression of the chemokine receptor CXCR7 in CXCR4-expressing human 143B osteosarcoma cells enhances lung metastasis of intratibial xenografts in SCID mice.

Reduced Latency in the Metastatic Niche Contributes to the More Aggressive Phenotype of LM8 Compared to Dunn Osteosarcoma Cells.

CXCR4 antibody treatment suppresses metastatic spread to the lung of intratibial human osteosarcoma xenografts in mice.