Jean-Claude Tardif

Optimus Primer: A PCR enrichment primer design program for next-generation sequencing of human exonic regions.

Safety and effectiveness of enoxaparin following fibrinolytic therapy: Results of the Acute Myocardial Infarction (AMI)-QUEBEC registry.

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Damming the genomic data flood using a comprehensive analysis and storage data structure.

Ivabradine reduces heart rate while preserving metabolic fluxes and energy status of healthy normoxic working hearts.

Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial.

Heart rate-associated mechanical stress impairs carotid but not cerebral artery compliance in dyslipidemic atherosclerotic mice.

Role of aldosterone on lung structural remodelling and right ventricular function in congestive heart failure.

Heart rate and use of beta-blockers in stable outpatients with coronary artery disease.

FTO genotype is associated with phenotypic variability of body mass index.

Transient receptor potential canonical-3 channel-dependent fibroblast regulation in atrial fibrillation.

Ankle-brachial index and cardiovascular outcomes in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial.

Imaging atherosclerosis with hybrid [18F]fluorodeoxyglucose positron emission tomography/computed tomography imaging: what Leonardo da Vinci could not see.

Randomized, placebo-controlled trial of mipomersen in patients with severe hypercholesterolemia receiving maximally tolerated lipid-lowering therapy.

Individual patient data meta-analysis for the clinical assessment of coronary computed tomography angiography: protocol of the Collaborative Meta-Analysis of Cardiac CT (CoMe-CCT).

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.

Favorable effects of insulin sensitizers pertinent to peripheral arterial disease in type 2 diabetes: results from the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial.

Alternative Imaging Modalities in Ischemic Heart Failure (AIMI-HF) IMAGE HF Project I-A: study protocol for a randomized controlled trial.

Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B).

Computed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project 1-C).

Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest.

Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure.

Optimisation of reference genes for gene-expression analysis in a rabbit model of left ventricular diastolic dysfunction.

Comparison of genotype clustering tools with rare variants.

Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits.

Effects of the high-density lipoprotein mimetic agent CER-001 on coronary atherosclerosis in patients with acute coronary syndromes: a randomized trial.

Hybrid FMT-MRI applied to in vivo atherosclerosis imaging.

Impact of chronic kidney disease on use of evidence-based therapy in stable coronary artery disease: a prospective analysis of 22,272 patients.

Defining the role of common variation in the genomic and biological architecture of adult human height.

Myocardial Infarction-Associated SNP at 6p24 Interferes With MEF2 Binding and Associates With PHACTR1 Expression Levels in Human Coronary Arteries.

Expression of phosphoinositide-specific phospholipase C isoforms in native endothelial cells.

Use of Anticoagulants and Antiplatelet Agents in Stable Outpatients with Coronary Artery Disease and Atrial Fibrillation. International CLARIFY Registry.

The effect of simvastatin treatment on endothelial cell response to shear stress and tumor necrosis factor alpha stimulation.

Impact of regular physical activity on weekly warfarin dose requirement.

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

Validating a bimodal intravascular ultrasound (IVUS) and near-infrared fluorescence (NIRF) catheter for atherosclerotic plaque detection in rabbits.

Calcium Signaling Pathway Genes RUNX2 and CACNA1C Are Associated With Calcific Aortic Valve Disease.

Testing the role of predicted gene knockouts in human anthropometric trait variation.

Pillbox Use and INR Stability in a Prospective Cohort of New Warfarin Users.

The Role of Biomarkers in Decreasing Risk of Cardiac Toxicity after Cancer Therapy.

Trait Hostility and Acute Inflammatory Responses to Stress in the Laboratory.

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.

Genotype-Dependent Effects of Dalcetrapib on Cholesterol Efflux and Inflammation: Concordance With Clinical Outcomes.

Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study (CAHHM) - a Pan Canadian cohort study.

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.

Arterial Effects of Canakinumab in Patients With Atherosclerosis and Type 2 Diabetes or Glucose Intolerance.

Psychological Profiles in the Prediction of Leukocyte Telomere Length in Healthy Individuals.

Effects of the P-Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention According to Timing of Infusion: Insights From the SELECT-ACS Trial.

Effect of treatment with 5-lipoxygenase inhibitor VIA-2291 (atreleuton) on coronary plaque progression: a serial CT angiography study.

Thrombospondin-1-Derived Peptide RFYVVMWK Improves the Adhesive Phenotype of CD34 Cells From Atherosclerotic Patients With Type 2 Diabetes.

Validating Intravascular Imaging with Serial Optical Coherence Tomography and Confocal Fluorescence Microscopy.

Beneficial Effects of Reconstituted High-Density Lipoprotein (rHDL) on Circulating CD34+ Cells in Patients after an Acute Coronary Syndrome.

Aldosterone Does Not Predict Cardiovascular Events Following Acute Coronary Syndrome in Patients Initially Without Heart Failure.

Assessment of Inter-Expert Variability and of an Automated Segmentation Method of 40 and 60 MHz IVUS Images of Coronary Arteries.

Rare and low-frequency coding variants alter human adult height.

JAK-STAT signalling and the atrial fibrillation promoting fibrotic substrate.

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.

Rationale and design of REDUCE-IT: Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial.

Fabricating Water Dispersible Superparamagnetic Iron Oxide Nanoparticles for Biomedical Applications through Ligand Exchange and Direct Conjugation.

Prognostic Value of Noninvasive Cardiovascular Testing in Patients With Stable Chest Pain: Insights From the PROMISE Trial (Prospective Multicenter Imaging Study for Evaluation of Chest Pain).

Dalcetrapib and anacetrapib differently impact HDL structure and function in rabbits and monkeys.

Diagnosis, Prevalence, Awareness, Treatment, Prevention, and Control of Hypertension in Cameroon: Protocol for a Systematic Review and Meta-Analysis of Clinic-Based and Community-Based Studies.

Role of B-Type Natriuretic Peptide and N-Terminal Prohormone BNP as Predictors of Cardiovascular Morbidity and Mortality in Patients With a Recent Coronary Event and Type 2 Diabetes Mellitus.

Rationale, design, and baseline characteristics of the CLARIFY registry of outpatients with stable coronary artery disease.

Polygenic determinants in extremes of high-density lipoprotein cholesterol.

Apolipoprotein A-I Modulates Atherosclerosis Through Lymphatic Vessel-Dependent Mechanisms in Mice.

Epigenetics and precision medicine in cardiovascular patients: from basic concepts to the clinical arena.

Association of Lipoprotein(a) With Risk of Recurrent Ischemic Events Following Acute Coronary Syndrome: Analysis of the dal-Outcomes Randomized Clinical Trial.

Exome-wide association study of plasma lipids in >300,000 individuals.

Perioperative THR-184 and AKI after Cardiac Surgery.

Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci.

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Echocardiographic validation of pulmonary hypertension due to heart failure with reduced ejection fraction in mice.

Rationale, design, and preliminary results of the Quebec Warfarin Cohort Study.

Sex, drugs, and heart failure: a sex-sensitive review of the evidence base behind current heart failure clinical guidelines.

Exchange protein activated by cyclic-adenosine monophosphate (Epac) regulates atrial fibroblast function and controls cardiac remodelling.

Potential impact of the 2017 ACC/AHA guideline on high blood pressure in normotensive patients with stable coronary artery disease: insights from the CLARIFY registry.

A comprehensive evaluation of the genetic architecture of sudden cardiac arrest.

Biomarkers and arrhythmia recurrence following radiofrequency ablation of atrial fibrillation.

Comprehensive and Reproducible Untargeted Lipidomic Workflow Using LC-QTOF Validated for Human Plasma Analysis.

Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol.

β-blockers, calcium antagonists, and mortality in stable coronary artery disease: an international cohort study.

Retinopathy, Neuropathy, and Subsequent Cardiovascular Events in Patients with Type 2 Diabetes and Acute Coronary Syndrome in the ELIXA: The Importance of Disease Duration.

Single-Molecule hsTnI and Short-Term Risk in Stable Patients With Chest Pain.

Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use.

Predictive Model for High-Risk Coronary Artery Disease.

Automatic IVUS lumen segmentation using a 3D adaptive helix model.

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

In Vivo Near-Infrared Fluorescence Imaging of Atherosclerosis Using Local Delivery of Novel Targeted Molecular Probes.

Subsequent Event Risk in Individuals With Established Coronary Heart Disease.

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.

PulmoBind Imaging Measures Reduction of Vascular Adrenomedullin Receptor Activity with Lack of effect of Sildenafil in Pulmonary Hypertension.

An N-/L-type calcium channel blocker, cilnidipine, suppresses autonomic, electrical, and structural remodelling associated with atrial fibrillation.

Blood pressure and burden of hypertension in Cameroon, a microcosm of Africa: a systematic review and meta-analysis of population-based studies.

Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians.

Diagnosis of obstructive coronary artery disease using computed tomography angiography in patients with stable chest pain depending on clinical probability and in clinically important subgroups: meta-analysis of individual patient data.

Cardiac inflammation and diastolic dysfunction in hypercholesterolemic rabbits.

Long-term outcomes of chronic coronary syndrome worldwide: insights from the international CLARIFY registry.

Relationship between physical activity and long-term outcomes in patients with stable coronary artery disease.

Cardiovascular risk scoring and magnetic resonance imaging detected subclinical cerebrovascular disease.

Beneficial effects of ivabradine in patients with heart failure, low ejection fraction, and heart rate above 77 b.p.m.

Inherited Chromosomally Integrated Human Herpesvirus 6 Demonstrates Tissue-Specific RNA Expression That Correlates with an Increased Antibody Immune Response.

Discordances between predicted and actual risk in obese patients with suspected cardiac ischaemia.

rs73185306 C/T Is Not a Predisposing Risk Factor for Inherited Chromosomally Integrated Human Herpesvirus 6A/B.

Does low-density lipoprotein cholesterol induce inflammation? If so, does it matter? Current insights and future perspectives for novel therapies.

Meta-analysis of Randomized Controlled Trials Assessing the Impact of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies on Mortality and Cardiovascular Outcomes.

Urotensin II, urotensin-related peptide, and their receptor in aortic valve stenosis.

REDUCE-IT USA: Results From the 3146 Patients Randomized in the United States.

Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction.

Investigational drugs in development for hypertriglyceridemia: a coming-of-age story.

Oral Anticoagulant Prescription Trends, Profile Use, and Determinants of Adherence in Patients with Atrial Fibrillation.

Chronic Kidney Disease Has a Graded Association with Death and Cardiovascular Outcomes in Stable Coronary Artery Disease: An Analysis of 21,911 Patients from the CLARIFY Registry.

Lipoprotein(a) Reduction in Persons with Cardiovascular Disease.

Simple risk models to predict cardiovascular death in patients with stable coronary artery disease.

Association of high-density lipoprotein particle concentration with cardiovascular risk following acute coronary syndrome: A case-cohort analysis of the dal-Outcomes trial.

Role of atrial arrhythmia and ventricular response in atrial fibrillation induced atrial remodelling.

Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease.

Study design of Dal-GenE, a pharmacogenetic trial targeting reduction of cardiovascular events with dalcetrapib.

Reduced Cognitive Assessment Scores Among Individuals With Magnetic Resonance Imaging-Detected Vascular Brain Injury.

Dalcetrapib Reduces Risk of New-Onset Diabetes in Patients With Coronary Heart Disease.

Site qualification and clinical interpretation standards for Tc-SPECT perfusion imaging in a multi-center study of MITNEC (Medical Imaging Trials Network of Canada).

Hyperglycaemia, ejection fraction and the risk of heart failure or cardiovascular death in patients with type 2 diabetes and a recent acute coronary syndrome.

Incident heart failure in outpatients with chronic coronary syndrome: results from the international prospective CLARIFY registry.

Autoantibody Signature in Cardiac Arrest.

Low-Dose Colchicine after Myocardial Infarction. Reply.

The Use of Random Forests to Identify Brain Regions on Amyloid and FDG PET Associated With MoCA Score.

Cost-effectiveness of low-dose colchicine after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT).

High-sensitivity C-reactive protein is associated with clonal hematopoiesis of indeterminate potential.

A genetic model of ivabradine recapitulates results from randomized clinical trials.

Population Pharmacokinetics of Candesartan in Patients with Chronic Heart Failure.

Comparison of Atrial Remodeling Caused by Sustained Atrial Flutter Versus Atrial Fibrillation.

Bias in natriuretic peptide-guided heart failure trials: time to improve guideline adherence using alternative approaches.

Immediate vs Delayed Stenting in ST-Elevation Myocardial Infarction: Rationale and Design of the International PRIMACY Bayesian Randomized Controlled Trial.

Time-to-treatment initiation of colchicine and cardiovascular outcomes after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT).

The inflammation-resolution promoting molecule resolvin-D1 prevents atrial proarrhythmic remodelling in experimental right heart disease.

A genetic association study of heart failure: more evidence for the role of BAG3 in idiopathic dilated cardiomyopathy.

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

The Polygenic and Monogenic Basis of Blood Traits and Diseases.

Distorting Effect of Immortal Time Bias on the Association Between Catheter Ablation for Atrial Fibrillation and Incident Stroke: Caveat Emptor.

REDUCE-IT INTERIM: accumulation of data across prespecified interim analyses to final results.

Blood pressure and mortality in patients with type 2 diabetes and a recent coronary event in the ELIXA trial.

Colchicine for Secondary Prevention of Cardiovascular Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Reduction in Revascularization With Icosapent Ethyl: Insights From REDUCE-IT Revascularization Analyses.

Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia.

Pulmonary Vein Stenosis After Atrial Fibrillation Ablation: Insights From the ADVICE Trial.

Diabetes, Brain Infarcts, Cognition, and Small Vessels in the Canadian Alliance for Healthy Hearts and Minds Study.

Colchicine for Secondary Cardiovascular Prevention in Coronary Disease.

Colchicine reduces lung injury in experimental acute respiratory distress syndrome.

Use of risk scores to identify lower and higher risk subsets among COMPASS-eligible patients with chronic coronary syndromes. Insights from the CLARIFY registry.

Anti-inflammatory therapy for COVID-19 infection: the case for colchicine.

The Canadian Alliance for Healthy Hearts and Minds: How Well Does It Reflect the Canadian Population?

Thermal tolerance and fish heart integrity: fatty acids profiles as predictors of species resilience.

ApoA-I mimetic does not improve left ventricular diastolic dysfunction in rabbits without aortic valve stenosis.

Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect.

Lessons from COLCOT and LoDoCo2: colchicine for secondary prevention in coronary artery disease.

Response to: 'Correspondence on 'Anti-inflammatory therapy for COVID-19 infection: the case for colchicine'' by Perricone .

Improved Segmentation of the Intracranial and Ventricular Volumes in Populations with Cerebrovascular Lesions and Atrophy Using 3D CNNs.

MK2-Deficient Mice Are Bradycardic and Display Delayed Hypertrophic Remodeling in Response to a Chronic Increase in Afterload.

Initiation of low-dose colchicine early after myocardial infarction.

Comparative effectiveness and safety of high-dose rivaroxaban and apixaban for atrial fibrillation: A propensity score-matched cohort study.

Pharmacogenomics of the Efficacy and Safety of Colchicine in COLCOT.

Cardiovascular risk of chronic coronary syndrome patients according to vascular phenotype, diabetes, and smoking.

Genetic meta-analysis of cancer diagnosis following statin use identifies new associations and implicates human leukocyte antigen (HLA) in women.

Lessons learned from large Cardiovascular Outcome Trials targeting inflammation in cardiovascular disease (CANTOS, CIRT, COLCOT and LoDoCo2).

Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality.

Role of Adenylate Cyclase 9 in the Pharmacogenomic Response to Dalcetrapib: Clinical Paradigm and Molecular Mechanisms in Precision Cardiovascular Medicine.

Long-Chain Acylcarnitines and Monounsaturated Fatty Acids Discriminate Heart Failure Patients According to Pulmonary Hypertension Status.

Vascular inflammation in moderate-to-severe atopic dermatitis is associated with enhanced Th2 response.

Prevalence, Incidence and Prognostic Implications of Left Bundle Branch Block in Patients with Chronic Coronary Syndromes (From the CLARIFY Registry).

Glucagon-Like Peptide 1 Receptor Agonists, Carotid Atherosclerosis, and Cardiovascular Outcomes.

Genetics of symptom remission in outpatients with COVID-19.

Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial.

Inhibition of the 3CL Protease and SARS-CoV-2 Replication by Dalcetrapib.

Lipoprotein (a): When to Measure and How to Treat?

International Observational Analysis of Evolution and Outcomes of Chronic Stable Angina: The Multinational CLARIFY Study.

Colchicine in the Management of Acute and Chronic Coronary Artery Disease.

Repurposing colchicine's journey in view of drug-to-drug interactions. A review.

Factors Associated With Burnout, Post-traumatic Stress and Anxio-Depressive Symptoms in Healthcare Workers 3 Months Into the COVID-19 Pandemic: An Observational Study.

Association of Atrial Fibrillation Burden With Health-Related Quality of Life After Atrial Fibrillation Ablation: Substudy of the Cryoballoon vs Contact-Force Atrial Fibrillation Ablation (CIRCA-DOSE) Randomized Clinical Trial.

Colchicine for Prevention of Atherothrombotic Events in Patients With Coronary Artery Disease: Review and Practical Approach for Clinicians.

Low-Dose Colchicine for the Management of Coronary Artery Disease.

The genomics of heart failure: design and rationale of the HERMES consortium.

SPECT imaging of pulmonary vascular disease in bleomycin-induced lung fibrosis using a vascular endothelium tracer.

Effect of Cognitive Reserve on the Association of Vascular Brain Injury With Cognition: Analysis of the PURE and CAHHM Studies.

Repurposing Colchicine for Heart Disease.

A sex-specific evolutionary interaction between and .

Comparative Reductions in Investigator-Reported and Adjudicated Ischemic Events in REDUCE-IT.

Impact of smoking on cardiovascular outcomes in patients with stable coronary artery disease.

Benefits of Icosapent Ethyl Across the Range of Kidney Function in Patients With Established Cardiovascular Disease or Diabetes: REDUCE-IT RENAL.

Icosapent Ethyl Reduces Ischemic Events in Patients With a History of Previous Coronary Artery Bypass Grafting: REDUCE-IT CABG.

The impact of reporting magnetic resonance imaging incidental findings in the Canadian alliance for healthy hearts and minds cohort.

Effect of Perindopril on Atrial Fibrillation Recurrence and Burden: Results of the Canadian Trial of Atrial Fibrillation (CTAF)-2.

Immunologic Dysregulation and Hypercoagulability as a Pathophysiologic Background in COVID-19 Infection and the Immunomodulating Role of Colchicine.

The power of genetic diversity in genome-wide association studies of lipids.

Chasing the storm: Recruiting non-hospitalized patients for a multi-site randomized controlled trial in the United States during the COVID-19 pandemic.

Colchicine in Cardiovascular Disease: In-Depth Review.

Normal sex and age-specific parameters in a multi-ethnic population: a cardiovascular magnetic resonance study of the Canadian Alliance for Healthy Hearts and Minds cohort.

Racial Disparities in Acute Coronary Syndrome Management Within a Universal Healthcare Context: Insights From the AMI-OPTIMA Trial.

Prevalence of diabetes and impact on cardiovascular events and mortality in patients with chronic coronary syndromes, across multiple geographical regions and ethnicities.

Apolipoprotein C-III reduction in subjects with moderate hypertriglyceridaemia and at high cardiovascular risk.

Predictive risk factors for hospitalization and response to colchicine in patients with COVID-19.

Deep Bayesian networks for uncertainty estimation and adversarial resistance of white matter hyperintensity segmentation.

Pattern of Atrial Fibrillation and Cognitive Function in Young Patients With Atrial Fibrillation and Low CHADS Score: Insights From the BRAIN-AF Trial.

Comparative Effectiveness and Safety of Low-Dose Oral Anticoagulants in Patients With Atrial Fibrillation.

Evaluation of Adiposity and Cognitive Function in Adults.

Construction of a femininity score in the UK Biobank and its association with angina diagnosis prior to myocardial infarction.

Leveraging large observational studies to discover genetic determinants of drug concentrations: A proof-of-concept study.

Hair cortisol change at COVID-19 pandemic onset predicts burnout among health personnel.

Cost-effectiveness of Icosapent Ethyl for High-risk Patients With Hypertriglyceridemia Despite Statin Treatment.

Aspirin for Primary Cardiovascular Prevention in Patients with Diabetes: Uncertainties and Opportunities.

Treatment With Icosapent Ethyl to Reduce Ischemic Events in Patients With Prior Percutaneous Coronary Intervention: Insights From REDUCE-IT PCI.

Clinical Correlates Identify ProBDNF and Thrombo-Inflammatory Markers as Key Predictors of Circulating p75 Extracellular Domain Levels in Older Adults.

Computed tomography angiography versus Agatston score for diagnosis of coronary artery disease in patients with stable chest pain: individual patient data meta-analysis of the international COME-CCT Consortium.

Impact of Icosapent Ethyl on Cardiovascular Risk Reduction in Patients With Heart Failure in REDUCE-IT.

Risk Estimates of Imminent Cardiovascular Death and Heart Failure Hospitalization Are Improved Using Serial Natriuretic Peptide Measurements in Patients With Coronary Artery Disease and Type 2 Diabetes.

Protein tyrosine phosphatase 1B regulates miR-208b-argonaute 2 association and thyroid hormone responsiveness in cardiac hypertrophy.

Correction to: Computed tomography angiography versus Agatston score for diagnosis of coronary artery disease in patients with stable chest pain: individual patient data meta-analysis of the international COME-CCT Consortium.

ExPheWas: a platform for cis-Mendelian randomization and gene-based association scans.

Prevention of Cardiovascular Events and Mortality With Icosapent Ethyl in Patients With Prior Myocardial Infarction.

Trajectory of patients consulting the emergency department for high blood pressure values.

Adenylate cyclase type 9 antagonizes cAMP accumulation and regulates endothelial signalling involved in atheroprotection.

A New Era: Immunotherapy Applied to Contemporary Cardiovascular Practice.

An association study of ABCG2 rs2231142 on the concentrations of allopurinol and its metabolites.

Low-dose colchicine and high-sensitivity C-reactive protein after myocardial infarction: A combined analysis using individual patient data from the COLCOT and LoDoCo-MI studies.

Pharmacogenomic study of heart failure and candesartan response from the CHARM programme.

Effects of Randomized Treatment With Icosapent Ethyl and a Mineral Oil Comparator on Interleukin-1β, Interleukin-6, C-Reactive Protein, Oxidized Low-Density Lipoprotein Cholesterol, Homocysteine, Lipoprotein(a), and Lipoprotein-Associated Phospholipase A2: A REDUCE-IT Biomarker Substudy.

Protein Biomarkers and Cardiovascular Outcomes in People With Type 2 Diabetes and Acute Coronary Syndrome: The ELIXA Biomarker Study.

Pharmacogenetics-guided dalcetrapib therapy after an acute coronary syndrome: the dal-GenE trial.

Effect of olezarsen targeting APOC-III on lipoprotein size and particle number measured by NMR in patients with hypertriglyceridemia.

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.

Potential effects of icosapent ethyl on cardiovascular outcomes in cigarette smokers: REDUCE-IT smoking.

Vascular burden and cognition: Mediating roles of neurodegeneration and amyloid PET.

A saturated map of common genetic variants associated with human height.

Inhibition of the Mechanistic Target of Rapamycin in Acute Myocardial Infarction.

Intra-individual comparison of F-sodium fluoride PET-CT and Tc bone scintigraphy with SPECT in patients with prostate cancer or breast cancer at high risk for skeletal metastases (MITNEC-A1): a multicentre, phase 3 trial.

Pharmacogenetics-guided dalcetrapib therapy after an acute coronary syndrome.

Improvement of non-invasive tests of liver steatosis and fibrosis as indicators for non-alcoholic fatty liver disease in type 2 diabetes mellitus patients with elevated cardiovascular risk profile using the PPAR-α/γ agonist aleglitazar.

Fourteen-Day Evolution of COVID-19 Symptoms during the Third Wave in Nonvaccinated Subjects and Effects of Hesperidin Therapy: A Randomized, Double-Blinded, Placebo-Controlled Study.

Dalcetrapib and anacetrapib increase apolipoprotein E-containing HDL in rabbits and humans.

Angiopoietin-like 2 is essential to aortic valve development in mice.

Evolution of burnout and psychological distress in healthcare workers during the COVID-19 pandemic: a 1-year observational study.

Effect of lixisenatide on natriuretic peptides in people with type 2 diabetes and recent acute coronary syndrome: The ELIXA trial.

Potassium reduction with sodium zirconium cyclosilicate in patients with heart failure.

Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.

Psychological distress, social support, and use of outpatient care among adult men and women with coronary artery disease or other non-cardiovascular chronic disease.

Optimal or standard control of systolic and diastolic blood pressure across risk factor categories in patients with chronic coronary syndromes.

Generalizability of the REDUCE-IT trial to South Asians with cardiovascular disease.

Colchicine reduces atherosclerotic plaque vulnerability in rabbits.

Amyloid-PET of the white matter: Relationship to free water, fiber integrity, and cognition in patients with dementia and small vessel disease.

Study of effect modifiers of genetically predicted CETP reduction.

A Cost-Effectiveness Analysis of Biomarkers for Risk Prediction in Atrial Fibrillation.

Novel Humanized Biosimulator to Predict Coronary Obstruction in High-Risk Valve-in-Valve Procedures.

Large scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy.

Cardiovascular Benefits of Icosapent Ethyl in Patients With and Without Atrial Fibrillation in REDUCE-IT.

Females present higher dose-adjusted drug concentrations of metoprolol and allopurinol/oxypurinol than males.

Inflammation contributes to cardiovascular risk in patients receiving statin therapy.

Race and Ethnicity With Atherosclerotic Cardiovascular Disease Outcomes Within a Universal Health Care System: Insights From the CARTaGENE Study.

Childhood maltreatment and leukocyte telomere length in men and women with chronic illness: an evaluation of moderating and mediating influences.

Somatic Mosaic Chromosomal Alterations and Death of Cardiovascular Disease Causes among Cancer Survivors.

Adcy9 Gene Inactivation Improves Cardiac Function After Myocardial Infarction in Mice.

Supplementation with a β-glucan tablet has no effect on hyperlipidemia: a randomized, placebo-controlled clinical trial.

Author Correction: The power of genetic diversity in genome-wide association studies of lipids.

Pharmacogenomic markers of metoprolol and α-OH-metoprolol concentrations: a genome-wide association study.

Autoimmune Atrial Fibrillation.

Association between coffee or tea consumption and cardiovascular outcomes in patients with stable coronary artery disease: Analysis from the CLARIFY registry.

CathAI: fully automated coronary angiography interpretation and stenosis estimation.

New-onset atrial fibrillation and chronic coronary syndrome in the CLARIFY registry.

Single Functional Group Platform for Multistimuli Responsivities: Tertiary Amine for CO/pH/ROS-Triggered Cargo Release in Nanocarriers.

Impact of amiodarone use on metoprolol concentrations, α-OH-metoprolol concentrations, metoprolol dosing and heart rate: A cross-sectional study.

Combination of computed tomography angiography with coronary artery calcium score for improved diagnosis of coronary artery disease: a collaborative meta-analysis of stable chest pain patients referred for invasive coronary angiography.

Effectiveness of icosapent ethyl on first and total cardiovascular events in patients with metabolic syndrome, but without diabetes: REDUCE-IT MetSyn.

An inflammation resolution-promoting intervention prevents atrial fibrillation caused by left ventricular dysfunction.

Cost-Effectiveness of Icosapent Ethyl in REDUCE-IT USA: Results From Patients Randomized in the United States.

Low-Dose Colchicine in Patients With Type 2 Diabetes and Recent Myocardial Infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT).

The role of cellular senescence in profibrillatory atrial remodelling associated with cardiac pathology.

Icosapent ethyl following acute coronary syndrome: the REDUCE-IT trial.

Impact of age on the predictive value of NT-proBNP in patients with diabetes mellitus stabilised after an acute coronary syndrome.

Low-Density Neutrophils Contribute to Subclinical Inflammation in Patients with Type 2 Diabetes.

Childhood Maltreatment and Leukocyte Telomere Length: Cardiac Vagal Activity Influences the Relation in Older Adults.

Knockdown of ANGPTL2 promotes left ventricular systolic dysfunction by upregulation of NOX4 in mice.

Pulmonary vascular disease and optical coherence tomography imaging in patients with Fontan palliation.

Lipoprotein(a) Blood Levels and Cardiovascular Risk Reduction With Icosapent Ethyl.

Atrial cardiomyocytes contribute to the inflammatory status associated with atrial fibrillation in right heart disease.

Inflammation in heart failure: pathophysiology and therapeutic strategies.

Low-Density Neutrophils and Neutrophil Extracellular Traps (NETs) Are New Inflammatory Players in Heart Failure.

Distinct spatial contributions of amyloid pathology and cerebral small vessel disease to hippocampal morphology.

Significance of the Wnt signaling pathway in coronary artery atherosclerosis.

Evaluation of stenoses using AI video models applied to coronary angiography.

Meta-Analysis of Genome-Wide Association Studies Reveals Genetic Mechanisms of Supraventricular Arrhythmias.

ERK3 is involved in regulating cardiac fibroblast function.

A Genome-Wide Association Study of Oxypurinol Concentrations in Patients Treated with Allopurinol.

Mitochondrial functions and fatty acid profiles in fish heart: an insight into physiological limitations linked with thermal tolerance and age.

Childhood Maltreatment and Body Mass Index in Older Adults With Chronic Illness.

Plasma myo-inositol elevation in heart failure: clinical implications and prognostic significance. Results from the BElgian and CAnadian MEtabolomics in HFpEF (BECAME-HF) research project.

Platelet extracellular vesicles preserve lymphatic endothelial cell integrity and enhance lymphatic vessel function.

The effectiveness of coronary computed tomography angiography and functional testing for the diagnosis of obstructive coronary artery disease: results from the individual patient data Collaborative Meta-Analysis of Cardiac CT (COME-CCT).

Soft nanoparticles as antimicrobial agents and carriers of microbiocides for enhanced inhibition activity.

Daily exposure to chlordecone, an organochlorine pesticide, increases cardiac fibrosis and atrial fibrillation vulnerability.

Colchicine improves clinical outcomes in patients with coronary disease, will it result in similar benefits in peripheral artery disease?

Chronic coronary syndromes without standard modifiable cardiovascular risk factors and outcomes: the CLARIFY registry.