Department of Pediatrics -Neurology,
Center for Drug Discovery,
Department of Neuroscience
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Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis.
Cell stem cell Oct, 2010 | Pubmed ID: 20887954
Systems biology approach to imaging of neural stem cells.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21279615
Adult human neurogenesis: from microscopy to magnetic resonance imaging.
Frontiers in neuroscience , 2011 | Pubmed ID: 21519376
Sparse non-negative generalized PCA with applications to metabolomics.
Bioinformatics (Oxford, England) Nov, 2011 | Pubmed ID: 21930672
Members of the high mobility group B protein family are dynamically expressed in embryonic neural stem cells.
Proteome science , 2013 | Pubmed ID: 23621913
Metabolomic approach to human brain spectroscopy identifies associations between clinical features and the frontal lobe metabolome in multiple sclerosis.
NeuroImage Nov, 2013 | Pubmed ID: 23751863
TM4SF20 Ancestral Deletion and Susceptibility to a Pediatric Disorder of Early Language Delay and Cerebral White Matter Hyperintensities.
American journal of human genetics Jun, 2013 | Pubmed ID: 23810381
Aberrant neural stem cell proliferation and increased adult neurogenesis in mice lacking chromatin protein HMGB2.
PloS one , 2013 | Pubmed ID: 24391977
Regularized Partial Least Squares with an Application to NMR Spectroscopy.
Statistical analysis and data mining Aug, 2013 | Pubmed ID: 24511361
Inferring metabolic networks using the Bayesian adaptive graphical lasso with informative priors.
Statistics and its interface Oct, 2013 | Pubmed ID: 24533172
MicroRNA profiling reveals unique miRNA signatures in IGF-1 treated embryonic striatal stem cell fate decisions in striatal neurogenesis in vitro.
BioMed research international , 2014 | Pubmed ID: 25254208
Decreased thalamic glutamate level in unmedicated adult obsessive-compulsive disorder patients detected by proton magnetic resonance spectroscopy.
Journal of affective disorders Jun, 2015 | Pubmed ID: 25819113
Neuronal hyperactivity accelerates depletion of neural stem cells and impairs hippocampal neurogenesis.
Cell stem cell May, 2015 | Pubmed ID: 25957904
Analytical strategies for studying stem cell metabolism.
Frontiers in biology Apr, 2015 | Pubmed ID: 26213533
Metabolomics of neurodegenerative diseases.
International review of neurobiology , 2015 | Pubmed ID: 26358890
Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling.
PLoS biology May, 2016 | Pubmed ID: 27228556
Altered neuronal spontaneous activity correlates with glutamate concentration in medial prefrontal cortex of major depressed females: An fMRI-MRS study.
Journal of affective disorders Sep, 2016 | Pubmed ID: 27235818
Spatial Mapping of Translational Diffusion Coefficients Using Diffusion Tensor Imaging: A Mathematical Description.
Concepts in magnetic resonance. Part A, Bridging education and research Jan, 2014 | Pubmed ID: 27441031
Ligand Independent and Subtype-Selective Actions of Thyroid Hormone Receptors in Human Adipose Derived Stem Cells.
PloS one , 2016 | Pubmed ID: 27732649
Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates.
eLife Dec, 2016 | Pubmed ID: 27966429
A Standardized Protocol for Stereotaxic Intrahippocampal Administration of Kainic Acid Combined with Electroencephalographic Seizure Monitoring in Mice.
Frontiers in neuroscience , 2017 | Pubmed ID: 28405182
Transgenic mouse models for studying adult neurogenesis.
Frontiers in biology Jun, 2016 | Pubmed ID: 28473846
A question of fate.
PLoS biology May, 2017 | Pubmed ID: 28505150
Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance.
eLife Jul, 2017 | Pubmed ID: 28699891
Quantitative real-time imaging of glutathione.
Nature communications 07, 2017 | Pubmed ID: 28703127
The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D.
Cell metabolism Nov, 2017 | Pubmed ID: 28965825
Multitype Bellman-Harris branching model provides biological predictors of early stages of adult hippocampal neurogenesis.
BMC systems biology Oct, 2017 | Pubmed ID: 28984196
Pattern Separation: A Potential Marker of Impaired Hippocampal Adult Neurogenesis in Major Depressive Disorder.
Frontiers in neuroscience , 2017 | Pubmed ID: 29123464
A simulation model of neuroprogenitor proliferation dynamics predicts age-related loss of hippocampal neurogenesis but not astrogenesis.
Scientific reports Nov, 2017 | Pubmed ID: 29184142
Radical and lunatic fringes modulate notch ligands to support mammalian intestinal homeostasis.
eLife Apr, 2018 | Pubmed ID: 29629872
Analytical Platforms and Techniques to Study Stem Cell Metabolism.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 30196417
Quantitative Real-Time Imaging of Glutathione with Subcellular Resolution.
Antioxidants & redox signaling 06, 2019 | Pubmed ID: 30358421
Metabolomics of mammalian brain reveals regional differences.
BMC systems biology 12, 2018 | Pubmed ID: 30577853
Imaging Mass Spectrometry: A New Tool to Assess Molecular Underpinnings of Neurodegeneration.
Metabolites Jul, 2019 | Pubmed ID: 31295847
Heterogeneity of Stem Cells in the Hippocampus.
Advances in experimental medicine and biology , 2019 | Pubmed ID: 31487017
Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2020 | Pubmed ID: 31896673
Adult neurogenesis, human after all (again): Classic, optimized, and future approaches.
Behavioural brain research Mar, 2020 | Pubmed ID: 31899214
The orphan nuclear receptor TLX: an emerging master regulator of cross-talk between microglia and neural precursor cells.
Neuronal signaling Jun, 2019 | Pubmed ID: 32271856
Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Oct, 2020 | Pubmed ID: 32712217
Mouse Models for Studying Hippocampal Adult Neural Stem Cell Biology.
Methods in molecular biology (Clifton, N.J.) , 2021 | Pubmed ID: 33606206
BASP1 labels neural stem cells in the neurogenic niches of mammalian brain.
Scientific reports Mar, 2021 | Pubmed ID: 33692421
Author Correction: BASP1 labels neural stem cells in the neurogenic niches of mammalian brain.
Scientific reports Oct, 2021 | Pubmed ID: 34608270
Glial PAMPering and DAMPening of Adult Hippocampal Neurogenesis.
Brain sciences Sep, 2021 | Pubmed ID: 34679362
Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2022 | Pubmed ID: 35333654
Spatial analysis of drug absorption, distribution, metabolism, and toxicology using mass spectrometry imaging.
Biochemical pharmacology Jul, 2022 | Pubmed ID: 35561842
Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel.
Life sciences in space research Nov, 2022 | Pubmed ID: 36336356
Targeting hippocampal neurogenesis to protect astronauts' cognition and mood from decline due to space radiation effects.
Life sciences in space research Nov, 2022 | Pubmed ID: 36336363
Region-specific denoising identifies spatial co-expression patterns and intra-tissue heterogeneity in spatially resolved transcriptomics data.
Nature communications Nov, 2022 | Pubmed ID: 36376296
Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation.
Cell reports Jan, 2023 | Pubmed ID: 36640327
PolyAMiner-Bulk: A Machine Learning Based Bioinformatics Algorithm to Infer and Decode Alternative Polyadenylation Dynamics from bulk RNA-seq data.
bioRxiv : the preprint server for biology Jan, 2023 | Pubmed ID: 36747700
SPA-STOCSY: An Automated Tool for Identification of Annotated and Non-Annotated Metabolites in High-Throughput NMR Spectra.
bioRxiv : the preprint server for biology Feb, 2023 | Pubmed ID: 36865102
NMRQNet: a deep learning approach for automatic identification and quantification of metabolites using Nuclear Magnetic Resonance (NMR) in human plasma samples.
bioRxiv : the preprint server for biology Mar, 2023 | Pubmed ID: 36909516
Mass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids.
Frontiers in molecular biosciences , 2023 | Pubmed ID: 37304070
SPA-STOCSY: an automated tool for identifying annotated and non-annotated metabolites in high-throughput NMR spectra.
Bioinformatics (Oxford, England) Oct, 2023 | Pubmed ID: 37792497
Generation of five induced pluripotent stem cell lines from patients with MECP2 Duplication Syndrome.
Stem cell research Feb, 2024 | Pubmed ID: 38154383
Editorial: Advances in the biological effects of ionizing radiation.
Frontiers in oncology , 2023 | Pubmed ID: 38234403
Metabolic bioactivation of antidepressants: advance and underlying hepatotoxicity.
Drug metabolism reviews , 2024 | Pubmed ID: 38311829
PolyAMiner-Bulk is a deep learning-based algorithm that decodes alternative polyadenylation dynamics from bulk RNA-seq data.
Cell reports methods Feb, 2024 | Pubmed ID: 38325383
MECP2-related disorders while gene-based therapies are on the horizon.
Frontiers in genetics , 2024 | Pubmed ID: 38410154
MALDI Imaging Mass Spectrometry Visualizes the Distribution of Antidepressant Duloxetine and Its Major Metabolites in Mouse Brain, Liver, Kidney, and Spleen Tissues.
Drug metabolism and disposition: the biological fate of chemicals Jun, 2024 | Pubmed ID: 38658163
Rigor and reproducibility in human brain organoid research: Where we are and where we need to go.
Stem cell reports Jun, 2024 | Pubmed ID: 38759644
1Department of Pediatrics -Neurology, Baylor College of Medicine,
2Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital,
3Department of Pathology & Immunology, Baylor College of Medicine,
4Center for Drug Discovery, Baylor College of Medicine,
5Department of Neuroscience, Baylor College of Medicine
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