Thomas Klonisch

INSL3 in the benign hyperplastic and neoplastic human prostate gland.

The roe deer as a model for studying seasonal regulation of testis function.

Dioxin exerts anti-estrogenic actions in a novel dioxin-responsive telomerase-immortalized epithelial cell line of the porcine oviduct (TERT-OPEC).

Relaxin enhances the oncogenic potential of human thyroid carcinoma cells.

Relaxin-like ligand-receptor systems are autocrine/paracrine effectors in tumor cells and modulate cancer progression and tissue invasiveness.

Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway.

The art of killing: double stroke with apoptin and survivin as a novel approach in cancer therapy.

Cancer stem cell markers in common cancers - therapeutic implications.

The cytoplasmic domain of proEGF negatively regulates motility and elastinolytic activity in thyroid carcinoma cells.

The C-terminal cytoplasmic domain of human proEGF is a negative modulator of body and organ weights in transgenic mice.

HMGA2 exhibits dRP/AP site cleavage activity and protects cancer cells from DNA-damage-induced cytotoxicity during chemotherapy.

Fetal-maternal exchange of multipotent stem/progenitor cells: microchimerism in diagnosis and disease.

S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3.

INSL3 has tumor-promoting activity in thyroid cancer.

Thyroid stem cells and cancer.

Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c.

Three-dimensional nuclear telomere architecture is associated with differential time to progression and overall survival in glioblastoma patients.

beta-Dystroglycan binds caveolin-1 in smooth muscle: a functional role in caveolae distribution and Ca2+ release.

Nuclear imaging in three dimensions: a unique tool in cancer research.

Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53.

Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle.

Epidermal growth factor cytoplasmic domain affects ErbB protein degradation by the lysosomal and ubiquitin-proteasome pathway in human cancer cells.

Autophagy regulates trans fatty acid-mediated apoptosis in primary cardiac myofibroblasts.

INSL5 is a novel marker for human enteroendocrine cells of the large intestine and neuroendocrine tumours.

The pentameric channel of COMPcc in complex with different fatty acids.

Peri-conceptional changes in maternal exposure to sewage sludge chemicals disturbs fetal thyroid gland development in sheep.

HMGA2 inhibits apoptosis through interaction with ATR-CHK1 signaling complex in human cancer cells.

Three-dimensional telomere dynamics in follicular thyroid cancer.

C1q-tumour necrosis factor-related protein 8 (CTRP8) is a novel interaction partner of relaxin receptor RXFP1 in human brain cancer cells.

Human cathelicidin LL-37-derived peptide IG-19 confers protection in a murine model of collagen-induced arthritis.

Prognostic nomograms to predict oncological outcome of thyroid cancers.

The changing face of thyroid cancer in a population-based cohort.

Membrane potential differences and GABAA receptor expression in hepatic tumor and non-tumor stem cells.

Chaperoning HMGA2 protein protects stalled replication forks in stem and cancer cells.

Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins.

Mechanisms of therapeutic resistance in cancer (stem) cells with emphasis on thyroid cancer cells.

Suppression of influenza A virus replication in human lung epithelial cells by noncytotoxic concentrations bafilomycin A1.

Platinum (IV) coiled coil nanotubes selectively kill human glioblastoma cells.

Characterization of the dystrophin-glycoprotein complex in airway smooth muscle: role of δ-sarcoglycan in airway responsiveness.

RAGE Mediates the Pro-Migratory Response of Extracellular S100A4 in Human Thyroid Cancer Cells.

Betacellulin transgenic mice develop urothelial hyperplasia and show sex-dependent reduction in urinary major urinary protein content.

Nuclear localized Akt enhances breast cancer stem-like cells through counter-regulation of p21(Waf1/Cip1) and p27(kip1).

RXFP1 is Targeted by Complement C1q Tumor Necrosis Factor-Related Factor 8 in Brain Cancer.

PDK2-mediated alternative splicing switches Bnip3 from cell death to cell survival.

Stage II differentiated thyroid cancer: A mixed bag.

High Mobility Group A2 protects cancer cells against telomere dysfunction.

Cancer stem cells, cancer-initiating cells and methods for their detection.

Biodistribution of negatively charged iron oxide nanoparticles (IONPs) in mice and enhanced brain delivery using lysophosphatidic acid (LPA).

Pelota Regulates Epidermal Differentiation by Modulating BMP and PI3K/AKT Signaling Pathways.

FDG-PET characteristics of Hürthle cell and follicular adenomas.

Structural commonality of C1q TNF-related proteins and their potential to activate relaxin/insulin-like family peptide receptor 1 signalling pathways in cancer cells.

Photodynamic N-TiO Nanoparticle Treatment Induces Controlled ROS-mediated Autophagy and Terminal Differentiation of Leukemia Cells.

Inhibition of autophagy inhibits the conversion of cardiac fibroblasts to cardiac myofibroblasts.

Population-based analysis of breast cancer treatment by intrinsic sub-type in Manitoba, Canada.

A prospective cohort study to assess the role of FDG-PET in differentiating benign and malignant follicular neoplasms.

Dynamics of three-dimensional telomere profiles of circulating tumor cells in patients with high-risk prostate cancer who are undergoing androgen deprivation and radiation therapies.

Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.

New frontiers in the treatment of colorectal cancer: Autophagy and the unfolded protein response as promising targets.

Corrigendum to "Epidermal Growth Factor Cytoplasmic Domain Affects ErbB Protein Degradation by the Lysosomal and Ubiquitin-Proteasome Pathway in Human Cancer Cells" [Neoplasia 14 (2012) 396-409].

Dovitinib enhances temozolomide efficacy in glioblastoma cells.

C1q/TNF-related protein 6 (CTRP6) links obesity to adipose tissue inflammation and insulin resistance.

Characterization of GPCRs in extracellular vesicle (EV).

Autophagy and the unfolded protein response promote profibrotic effects of TGF-β in human lung fibroblasts.

Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response.

Ubiquitin C-terminal hydrolase isozyme L1 is associated with shelterin complex at interstitial telomeric sites.

Simple, Hackable, Size-Selective, Amine-Functionalized Fe-Oxide Nanoparticles for Biomedical Applications.

Autophagy modulates transforming growth factor beta 1 induced epithelial to mesenchymal transition in non-small cell lung cancer cells.

C1q/TNF-related peptide 8 (CTRP8) promotes temozolomide resistance in human glioblastoma.

Inhibitor of DNA Binding 2 Inhibits Epithelial-Mesenchymal Transition via Up-Regulation of Notch3 in Breast Cancer.

HMGA2 as a functional antagonist of PARP1 inhibitors in tumor cells.

Maternal smoking and high BMI disrupt thyroid gland development.

Statins: a new approach to combat temozolomide chemoresistance in glioblastoma.

A radial microfluidic platform for higher throughput chemotaxis studies with individual gradient control.

Claudin 1 Is Highly Upregulated by PKC in MCF7 Human Breast Cancer Cells and Correlates Positively with PKCε in Patient Biopsies.

Emerging roles for the relaxin/RXFP1 system in cancer therapy.

Editorial to the mini-review series on relaxin, related peptides and receptors?

Simvastatin increases temozolomide-induced cell death by targeting the fusion of autophagosomes and lysosomes.

Polymeric mesoporous silica nanoparticles as a pH-responsive switch to control doxorubicin intracellular delivery.

Zika Infection Disrupts Proteins Involved in the Neurosensory System.

Investigations on T cell transmigration in a human skin-on-chip (SoC) model.

Novel CTRP8-RXFP1-JAK3-STAT3 axis promotes Cdc42-dependent actin remodeling for enhanced filopodia formation and motility in human glioblastoma cells.

Slow Off-Rate Modified Aptamer (SOMAmer) Proteomic Analysis of Patient-Derived Malignant Glioma Identifies Distinct Cellular Proteomes.

Wnt and PI3K/Akt/mTOR Survival Pathways as Therapeutic Targets in Glioblastoma.

Genes of the Ubiquitin Proteasome System Qualify as Differential Markers in Malignant Glioma of Astrocytic and Oligodendroglial Origin.

Ubiquitin Proteasome Gene Signatures in Ependymoma Molecular Subtypes.

Nuclear High Mobility Group A2 (HMGA2) Interactome Revealed by Biotin Proximity Labeling.

Human C1q Tumor Necrosis Factor 8 (CTRP8) defines a novel tryptase+ mast cell subpopulation in the prostate cancer microenvironment.

C1q/TNF-Related Proteins 1, 6 and 8 Are Involved in Corneal Epithelial Wound Closure by Targeting Relaxin Receptor RXFP1 In Vitro.

DUBing Primary Tumors of the Central Nervous System: Regulatory Roles of Deubiquitinases.

Breast Tumor Metastasis and Its Microenvironment: It Takes Both Seed and Soil to Grow a Tumor and Target It for Treatment.

Characterization of HMGA2 variants expands the spectrum of Silver-Russell syndrome.

Overcoming brain-derived therapeutic resistance in HER2+ breast cancer brain metastasis.

C1QTNF Related protein 8 (CTRP8) is a marker of myeloid derived innate immune cell populations in the human breast cancer microenvironment.