Tumour Targeting Laboratory
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Integral membrane protease fibroblast activation protein sensitizes fibrosarcoma to chemotherapy and alters cell death mechanisms.
Apoptosis : an international journal on programmed cell death Nov, 2015 | Pubmed ID: 26342814
Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways.
Oncotarget Nov, 2015 | Pubmed ID: 26517691
Molecular Imaging and Quantitation of EphA2 Expression in Xenograft Models with 89Zr-DS-8895a.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 06, 2016 | Pubmed ID: 26940768
Engineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancers.
EJNMMI research Dec, 2016 | Pubmed ID: 26983636
Fluorine-18 radiolabeling of a nitrophenyl sulfoxide and its evaluation in an SK-RC-52 model of tumor hypoxia.
Journal of labelled compounds & radiopharmaceuticals 08, 2016 | Pubmed ID: 27435268
L-Tyrosine Confers Residualizing Properties to a d-Amino Acid-Rich Residualizing Peptide for Radioiodination of Internalizing Antibodies.
Molecular imaging , 2016 | Pubmed ID: 27457521
and Evaluation of Zr-DS-8273a as a Theranostic for Anti-Death Receptor 5 Therapy.
Theranostics , 2016 | Pubmed ID: 27924159
Effect of Structural Modifications to Glyoxal-bis(thiosemicarbazonato)copper(II) Complexes on Cellular Copper Uptake, Copper-Mediated ATP7A Trafficking, and P-Glycoprotein Mediated Efflux.
Journal of medicinal chemistry Feb, 2018 | Pubmed ID: 29232129
Molecular imaging of T cell co-regulator factor B7-H3 with Zr-DS-5573a.
Theranostics , 2018 | Pubmed ID: 30128047
Smac mimetics LCL161 and GDC-0152 inhibit osteosarcoma growth and metastasis in mice.
BMC cancer Sep, 2019 | Pubmed ID: 31521127
Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity.
Nature communications Nov, 2019 | Pubmed ID: 31757939
Synthesis and validation of [F]mBPET-1, a fluorine-18 labelled mTOR inhibitor derivative based on a benzofuran backbone.
EJNMMI radiopharmacy and chemistry Jan, 2020 | Pubmed ID: 31974638
Targeting and Efficacy of Novel mAb806-Antibody-Drug Conjugates in Malignant Mesothelioma.
Pharmaceuticals (Basel, Switzerland) Oct, 2020 | Pubmed ID: 33023139
Synthesis and fluorine-18 radiolabeling of a phospholipid as a PET imaging agent for prostate cancer.
Nuclear medicine and biology Feb, 2021 | Pubmed ID: 33310350
Radiolabelling and preclinical characterization of Zr-Df-radiolabelled bispecific anti-PD-L1/TGF-βRII fusion protein bintrafusp alfa.
European journal of nuclear medicine and molecular imaging Sep, 2021 | Pubmed ID: 33608805
Tumor volumes as a predictor of response to the anti-EGFR antibody drug conjugate depatuxizumab mafadotin.
Neuro-oncology advances , 2021 | Pubmed ID: 34549181
F Site-Specific Labelling of a Single-Chain Antibody against Activated Platelets for the Detection of Acute Thrombosis in Positron Emission Tomography.
International journal of molecular sciences Jun, 2022 | Pubmed ID: 35805892
F-labeling and initial in vivo evaluation of a Hitomi peptide for imaging tissue transglutaminase 2.
Nuclear medicine and biology , 2023 | Pubmed ID: 36502585
Bromodomain and extraterminal protein-targeted probe enables tumour visualisation using positron emission tomography.
Chemical communications (Cambridge, England) Mar, 2023 | Pubmed ID: 36809538
Automated radiosynthesis of [Zr]Zr-DFOSq-Durvalumab for imaging of PD-L1 expressing tumours in vivo.
Nuclear medicine and biology , 2023 | Pubmed ID: 37224789
Preclinical radiolabeling, in vivo biodistribution and positron emission tomography of a novel pyrrolobenzodiazepine (PBD)-based antibody drug conjugate targeting ASCT2.
Nuclear medicine and biology , 2023 | Pubmed ID: 37473513
Radiolabelling and preclinical characterisation of [Zr]Zr-Df-ATG-101 bispecific to PD-L1/4-1BB.
European journal of nuclear medicine and molecular imaging Sep, 2024 | Pubmed ID: 38730087
An Anti-VEGF-B Antibody Reduces Abnormal Tumor Vasculature and Enhances the Effects of Chemotherapy.
Cancers May, 2024 | Pubmed ID: 38791979
Targeting of immune checkpoint regulator V-domain Ig suppressor of T-cell activation (VISTA) with Zr-labelled CI-8993.
European journal of nuclear medicine and molecular imaging Nov, 2024 | Pubmed ID: 39060374
Targeting Fn14 as a therapeutic target for cachexia reprograms the glycolytic pathway in tumour and brain in mice.
European journal of nuclear medicine and molecular imaging Nov, 2024 | Pubmed ID: 39060375
Characterization of an Estrogen Receptor α-Selective F-Estradiol PET Tracer.
World journal of nuclear medicine Sep, 2024 | Pubmed ID: 39170834
Correction to: Targeting of immune checkpoint regulator V-domain Ig suppressor of T-cell activation (VISTA) with Zr-labelled CI-8993.
European journal of nuclear medicine and molecular imaging Nov, 2024 | Pubmed ID: 39186103
DNA-Dependent Protein Kinase Inhibitor Peposertib Enhances Efficacy of Lu-Based Radioimmunotherapy in Preclinical Models of Prostate and Renal Cell Carcinoma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine Mar, 2025 | Pubmed ID: 39884775
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