Robert M. Berne Cardiovascular Research Center,
Department of Molecular Physiology and Biological Physics
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Inward rectifier potassium (Kir2.1) channels as end-stage boosters of endothelium-dependent vasodilators.
The Journal of physiology Jun, 2016 | Pubmed ID: 26840527
Gain-of-function mutation in TRPV4 identified in patients with osteonecrosis of the femoral head.
Journal of medical genetics Oct, 2016 | Pubmed ID: 27330106
Non-Endoplasmic Reticulum-Based Calr (Calreticulin) Can Coordinate Heterocellular Calcium Signaling and Vascular Function.
Arteriosclerosis, thrombosis, and vascular biology Jan, 2018 | Pubmed ID: 29122814
Nitric Oxide-Dependent Feedback Loop Regulates Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Cooperativity and Endothelial Function in Small Pulmonary Arteries.
Journal of the American Heart Association Dec, 2017 | Pubmed ID: 29275372
TRPV4 (Transient Receptor Potential Vanilloid 4) Channel-Dependent Negative Feedback Mechanism Regulates G Protein-Coupled Receptor-Induced Vasoconstriction.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2018 | Pubmed ID: 29301784
RSK2 contributes to myogenic vasoconstriction of resistance arteries by activating smooth muscle myosin and the Na/H exchanger.
Science signaling Oct, 2018 | Pubmed ID: 30377223
Calcium signals that determine vascular resistance.
Wiley interdisciplinary reviews. Systems biology and medicine Sep, 2019 | Pubmed ID: 30884210
Novel Regulators and Targets of Redox Signaling in Pulmonary Vasculature.
Current opinion in physiology Jun, 2019 | Pubmed ID: 31406951
Loss of Endothelial FTO Antagonizes Obesity-Induced Metabolic and Vascular Dysfunction.
Circulation research Jan, 2020 | Pubmed ID: 31801409
Local Peroxynitrite Impairs Endothelial Transient Receptor Potential Vanilloid 4 Channels and Elevates Blood Pressure in Obesity.
Circulation Apr, 2020 | Pubmed ID: 32008372
Endothelial calreticulin deletion impairs endothelial function in aged mice.
American journal of physiology. Heart and circulatory physiology May, 2020 | Pubmed ID: 32196361
Endothelial TRPV4 channels and vasodilator reactivity.
Current topics in membranes , 2020 | Pubmed ID: 32402646
Mechanisms underlying selective coupling of endothelial Ca signals with eNOS vs. IK/SK channels in systemic and pulmonary arteries.
The Journal of physiology Sep, 2020 | Pubmed ID: 32463112
Technical brief: Direct, real-time electrochemical measurement of nitric oxide in ex vivo cultured human corneoscleral segments.
Molecular vision , 2020 | Pubmed ID: 32565671
Role of the purinergic signaling network in lung ischemia-reperfusion injury.
Current opinion in organ transplantation Apr, 2021 | Pubmed ID: 33651003
A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability.
Science signaling Mar, 2021 | Pubmed ID: 33653920
Calcium Signal Profiles in Vascular Endothelium from Cdh5-GCaMP8 and Cx40-GCaMP2 Mice.
Journal of vascular research , 2021 | Pubmed ID: 33706307
The Calcium Signaling Mechanisms in Arterial Smooth Muscle and Endothelial Cells.
Comprehensive Physiology Apr, 2021 | Pubmed ID: 33792900
Extra-Nuclear Functions of the Transcription Factor Grainyhead-Like 3 in the Endothelium-Interaction with Endothelial Nitric Oxide Synthase.
Antioxidants (Basel, Switzerland) Mar, 2021 | Pubmed ID: 33799664
Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2021 | Pubmed ID: 33853948
Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2021 | Pubmed ID: 33879616
Endothelial Transient Receptor Potential Vanilloid 4 Channels Mediate Lung Ischemia-Reperfusion Injury.
The Annals of thoracic surgery Apr, 2022 | Pubmed ID: 33961815
Guidelines for the measurement of vascular function and structure in isolated arteries and veins.
American journal of physiology. Heart and circulatory physiology Jul, 2021 | Pubmed ID: 33989082
Endothelial pannexin 1-TRPV4 channel signaling lowers pulmonary arterial pressure in mice.
eLife Sep, 2021 | Pubmed ID: 34490843
Role of TRP ion channels in cerebral circulation and neurovascular communication.
Neuroscience letters Nov, 2021 | Pubmed ID: 34560190
Mechanosensitive Angiotensin II Receptor Signaling in Pressure-Induced Vasoconstriction.
Journal of the American Heart Association Feb, 2022 | Pubmed ID: 35156384
Reply to De Mey et al.
American journal of physiology. Heart and circulatory physiology Apr, 2022 | Pubmed ID: 35324332
Reply to Boedtkjer and Aalkjaer.
American journal of physiology. Heart and circulatory physiology Apr, 2022 | Pubmed ID: 35324334
Novel Smooth Muscle Ca-Signaling Nanodomains in Blood Pressure Regulation.
Circulation Aug, 2022 | Pubmed ID: 35758040
Endothelial TRPV4 channels in lung edema and injury.
Current topics in membranes , 2022 | Pubmed ID: 36210151
Endothelial alpha globin is a nitrite reductase.
Nature communications Oct, 2022 | Pubmed ID: 36302779
Endothelial IK and SK channel activation decreases pulmonary arterial pressure and vascular remodeling in pulmonary hypertension.
Pulmonary circulation Jan, 2023 | Pubmed ID: 36686408
Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1.
JCI insight May, 2023 | Pubmed ID: 37014698
FHL5 Controls Vascular Disease-Associated Gene Programs in Smooth Muscle Cells.
Circulation research Apr, 2023 | Pubmed ID: 37017084
Purinergic P2Y2 Receptor-Induced Activation of Endothelial TRPV4 Channels Mediates Lung Ischemia-Reperfusion Injury.
bioRxiv : the preprint server for biology May, 2023 | Pubmed ID: 37397979
The Polyanionic Drug Suramin Neutralizes Histones and Prevents Endotheliopathy.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2023 | Pubmed ID: 37405700
Purinergic P2Y2 receptor-induced activation of endothelial TRPV4 channels mediates lung ischemia-reperfusion injury.
Science signaling Oct, 2023 | Pubmed ID: 37874885
Pannexin-3 stabilizes the transcription factor Bcl6 in a channel-independent manner to protect against vascular oxidative stress.
Science signaling Jan, 2024 | Pubmed ID: 38289985
The endothelium: gatekeeper to lung ischemia-reperfusion injury.
Respiratory research Apr, 2024 | Pubmed ID: 38637760
Transient receptor potential vanilloid 4 channel inhibition attenuates lung ischemia-reperfusion injury in a porcine lung transplant model.
The Journal of thoracic and cardiovascular surgery Oct, 2024 | Pubmed ID: 38678474
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