Department of Chemistry,
Materials and Chemical Engineering "Giulio Natta",
Department of Chemistry, Materials and Chemical Engineering "Giulio Natta"
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The effect of media perfusion on three-dimensional cultures of human chondrocytes: integration of experimental and computational approaches.
Biorheology , 2004 | Pubmed ID: 15299272
Contact pressures at grafted cartilage lesions in the knee.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA Sep, 2005 | Pubmed ID: 16170578
Modeling evaluation of the fluid-dynamic microenvironment in tissue-engineered constructs: a micro-CT based model.
Biotechnology and bioengineering Feb, 2006 | Pubmed ID: 16224789
Prediction of the micro-fluid dynamic environment imposed to three-dimensional engineered cell systems in bioreactors.
Journal of biomechanics , 2006 | Pubmed ID: 16389082
Biomechanical analysis of cages for posterior lumbar interbody fusion.
Medical engineering & physics Jan, 2007 | Pubmed ID: 16563847
Loss in mechanical contact of cementless acetabular prostheses due to post-operative weight bearing: a biomechanical model.
Medical engineering & physics Mar, 2007 | Pubmed ID: 16569508
The effect of hydrodynamic shear on 3D engineered chondrocyte systems subject to direct perfusion.
Biorheology , 2006 | Pubmed ID: 16912395
Engineered tissue as a model to study cell and tissue function from a biophysical perspective.
Current drug discovery technologies Dec, 2006 | Pubmed ID: 17430102
Engineered cartilage constructs subject to very low regimens of interstitial perfusion.
Biorheology , 2008 | Pubmed ID: 18836246
Comparative chondrogenesis of human cells in a 3D integrated experimental-computational mechanobiology model.
Biomechanics and modeling in mechanobiology Apr, 2011 | Pubmed ID: 20549292
Breakthroughs in computational modeling of cartilage regeneration in perfused bioreactors.
IEEE transactions on bio-medical engineering Dec, 2011 | Pubmed ID: 21813363
Two-photon laser polymerization: from fundamentals to biomedical application in tissue engineering and regenerative medicine.
Journal of applied biomaterials & functional materials Jun, 2012 | Pubmed ID: 22562455
Three-dimensional structural niches engineered via two-photon laser polymerization promote stem cell homing.
Acta biomaterialia Jan, 2013 | Pubmed ID: 22922332
An opto-structural method to estimate the stress-strain field induced by cell contraction on substrates of controlled stiffness in vitro.
Journal of applied biomaterials & functional materials Dec, 2013 | Pubmed ID: 23413127
Characterization of articular chondrocytes isolated from 211 osteoarthritic patients.
Cell and tissue banking Mar, 2014 | Pubmed ID: 23549979
Autologous intramuscular transplantation of engineered satellite cells induces exosome-mediated systemic expression of Fukutin-related protein and rescues disease phenotype in a murine model of limb-girdle muscular dystrophy type 2I.
Human molecular genetics Oct, 2017 | Pubmed ID: 28666318
Scaling-Up Techniques for the Nanofabrication of Cell Culture Substrates via Two-Photon Polymerization for Industrial-Scale Expansion of Stem Cells.
Materials (Basel, Switzerland) Jan, 2017 | Pubmed ID: 28772424
Secretome released from hydrogel-embedded adipose mesenchymal stem cells protects against the Parkinson's disease related toxin 6-hydroxydopamine.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V , | Pubmed ID: 28965958
Human bone perivascular niche-on-a-chip for studying metastatic colonization.
Proceedings of the National Academy of Sciences of the United States of America 02, 2018 | Pubmed ID: 29363599
Development and biological validation of a cyclic stretch culture system for the ex vivo engineering of tendons.
The International journal of artificial organs , | Pubmed ID: 29781355
The effect of polyurethane scaffold surface treatments on the adhesion of chondrocytes subjected to interstitial perfusion culture.
Tissue engineering and regenerative medicine Aug, 2016 | Pubmed ID: 30603418
Influence of the static magnetic field on cell response in a miniaturized optically accessible bioreactor for 3D cell culture.
Biomedical microdevices Mar, 2019 | Pubmed ID: 30868253
An Organ-On-A-Chip Engineered Platform to Study the Microbiota-Gut-Brain Axis in Neurodegeneration.
Trends in molecular medicine Sep, 2019 | Pubmed ID: 31422037
Mechanical regulation of nucleocytoplasmic translocation in mesenchymal stem cells: characterization and methods for investigation.
Biophysical reviews Oct, 2019 | Pubmed ID: 31628607
iPS, organoids and 3D models as advanced tools for in vitro toxicology.
ALTEX , 2020 | Pubmed ID: 31960938
Advantages and limitations of a supernegative GFP in facilitating MyoD intracellular tracking.
Methods and applications in fluorescence Mar, 2020 | Pubmed ID: 32092706
Lamin A/C Mechanotransduction in Laminopathies.
Cells May, 2020 | Pubmed ID: 32456328
Bioengineering tools to speed up the discovery and preclinical testing of vaccines for SARS-CoV-2 and therapeutic agents for COVID-19.
Theranostics , 2020 | Pubmed ID: 32641977
Advances in Tissue Engineering and Innovative Fabrication Techniques for 3-D-Structures: Translational Applications in Neurodegenerative Diseases.
Cells Jul, 2020 | Pubmed ID: 32646008
Effect of the 3D Artificial Nichoid on the Morphology and Mechanobiological Response of Mesenchymal Stem Cells Cultured In Vitro.
Cells 08, 2020 | Pubmed ID: 32796521
Dissecting the Effect of a 3D Microscaffold on the Transcriptome of Neural Stem Cells with Computational Approaches: A Focus on Mechanotransduction.
International journal of molecular sciences Sep, 2020 | Pubmed ID: 32942778
Nonlinear Optical Microscopy: From Fundamentals to Applications in Live Bioimaging.
Frontiers in bioengineering and biotechnology , 2020 | Pubmed ID: 33163482
Neural precursors cells expanded in a 3D micro-engineered niche present enhanced therapeutic efficacy .
Nanotheranostics , 2021 | Pubmed ID: 33391972
The nuclear import of the transcription factor MyoD is reduced in mesenchymal stem cells grown in a 3D micro-engineered niche.
Scientific reports 02, 2021 | Pubmed ID: 33542304
Intracellular label-free detection of mesenchymal stem cell metabolism within a perivascular niche-on-a-chip.
Lab on a chip , | Pubmed ID: 33605282
Transcriptome Analysis of Subcutaneous Adipose Tissue from Severely Obese Patients Highlights Deregulation Profiles in Coding and Non-Coding Oncogenes.
International journal of molecular sciences Feb, 2021 | Pubmed ID: 33671464
RNA-seq Characterization of Sex-Differences in Adipose Tissue of Obesity Affected Patients: Computational Analysis of Differentially Expressed Coding and Non-Coding RNAs.
Journal of personalized medicine Apr, 2021 | Pubmed ID: 33924951
A Human Neurovascular Unit On-a-Chip.
Methods in molecular biology (Clifton, N.J.) , 2022 | Pubmed ID: 34520009
Transcriptional characterization of subcutaneous adipose tissue in obesity affected women highlights metabolic dysfunction and implications for lncRNAs.
Genomics Nov, 2021 | Pubmed ID: 34555498
Neural Precursor Cells Expanded Inside the 3D Micro-Scaffold Nichoid Present Different Non-Coding RNAs Profiles and Transcript Isoforms Expression: Possible Epigenetic Modulation by 3D Growth.
Biomedicines Aug, 2021 | Pubmed ID: 34572306
α-Synuclein antisense transcript SNCA-AS1 regulates synapses- and aging-related genes suggesting its implication in Parkinson's disease.
Aging cell Dec, 2021 | Pubmed ID: 34799977
RNA-seq dataset of subcutaneous adipose tissue: Transcriptional differences between obesity and healthy women.
Data in brief Dec, 2021 | Pubmed ID: 34901353
Characterization of the Microflow Through 3D Synthetic Niche Microenvironments Hosted in a Millifluidic Bioreactor.
Frontiers in bioengineering and biotechnology , 2021 | Pubmed ID: 34976990
RNA Molecular Signature Profiling in PBMCs of Sporadic ALS Patients: HSP70 Overexpression Is Associated with Nuclear SOD1.
Cells Jan, 2022 | Pubmed ID: 35053410
Patients' Stem Cells Differentiation in a 3D Environment as a Promising Experimental Tool for the Study of Amyotrophic Lateral Sclerosis.
International journal of molecular sciences May, 2022 | Pubmed ID: 35628156
Oxygen Sensing in Neurodegenerative Diseases: Current Mechanisms, Implication of Transcriptional Response, and Pharmacological Modulation.
Antioxidants & redox signaling Jan, 2023 | Pubmed ID: 35793106
Effect of 3D Synthetic Microscaffold Nichoid on the Morphology of Cultured Hippocampal Neurons and Astrocytes.
Cells Jun, 2022 | Pubmed ID: 35805092
Pectin-based bioinks for 3D models of neural tissue produced by a pH-controlled kinetics.
Frontiers in bioengineering and biotechnology , 2022 | Pubmed ID: 36619394
Identification of a novel pathway in sporadic Amyotrophic Lateral Sclerosis mediated by the long non-coding RNA ZEB1-AS1.
Neurobiology of disease Mar, 2023 | Pubmed ID: 36736597
Unravelling the mechanotransduction pathways in Alzheimer's disease.
Journal of biological engineering Mar, 2023 | Pubmed ID: 36978103
Bone Marrow Mesenchymal Stem Cells Expanded Inside the Nichoid Micro-Scaffold: a Focus on Anti-Inflammatory Response.
Regenerative engineering and translational medicine Mar, 2023 | Pubmed ID: 37363698
3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal stem cells.
APL bioengineering Sep, 2023 | Pubmed ID: 37692376
label-free tissue histology through a microstructured imaging window.
APL bioengineering Mar, 2024 | Pubmed ID: 38222895
The Impact of 3D Nichoids and Matrix Stiffness on Primary Malignant Mesothelioma Cells.
Genes Feb, 2024 | Pubmed ID: 38397189
Zwitterionic nanoparticles for thermally activated drug delivery in hyperthermia cancer treatment.
Nanoscale Jul, 2024 | Pubmed ID: 38884523
The molecular basis of the anticancer effect of statins.
Scientific reports Aug, 2024 | Pubmed ID: 39217242
Non-Negative Matrix Tri-Factorization for Representation Learning in Multi-Omics Datasets with Applications to Drug Repurposing and Selection.
International journal of molecular sciences Sep, 2024 | Pubmed ID: 39273521
A millifluidic bioreactor allows the long term culture of primary lymphocytes or CD34 hematopoietic cells while allowing the detection of tumorigenic expansion.
Frontiers in bioengineering and biotechnology , 2024 | Pubmed ID: 39416278
A 3D millifluidic model of a dermal perivascular microenvironment on a chip.
Lab on a chip Jan, 2025 | Pubmed ID: 39757968
Alessandra Nardini1,2,3,
Behjat Sadat Kariman4,
Mario Marini5,
Conci Conci1,
Marco Grassi1,
Margaux Bouzin5,
Maddalena Collini5,
Roberto Osellame2,
Giulio Cerullo4,
Manuela Teresa Raimondi1,
Giuseppe Chirico5,
Rebeca Martínez Vázquez2
1Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano,
2Istituto di Fotonica e Nanotecnologie (IFN), Consiglio Nazionale delle Ricerche (CNR),
3Department of Experimental Medicine, Università del Salento,
4Department of Physics, Politecnico di Milano,
5Department of Physics, Università di Milano-Bicocca
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