Constance Cepko

Profile of the genes expressed in the human peripheral retina, macula, and retinal pigment epithelium determined through serial analysis of gene expression (SAGE).

Sox-9 and cDachsund-2 expression in the developing chick telencephalon.

Mutations in the inosine monophosphate dehydrogenase 1 gene (IMPDH1) cause the RP10 form of autosomal dominant retinitis pigmentosa.

The mouse Crx 5'-upstream transgene sequence directs cell-specific and developmentally regulated expression in retinal photoreceptor cells.

Ena/VASP proteins regulate cortical neuronal positioning.

The chicken RaxL gene plays a role in the initiation of photoreceptor differentiation.

The dorsal-ventral axis of the neural retina is divided into multiple domains of restricted gene expression which exhibit features of lineage compartments.

Stem cells that know their place.

Irx4-mediated regulation of Slit1 expression contributes to the definition of early axonal paths inside the retina.

MicroSAGE is highly representative and reproducible but reveals major differences in gene expression among samples obtained from similar tissues.

Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina.

Electroporation and RNA interference in the rodent retina in vivo and in vitro.

Thyroid hormone and retinal development: an emerging field.

Inner retinal abnormalities in a mouse model of Leber's congenital amaurosis.

Rb regulates proliferation and rod photoreceptor development in the mouse retina.

A role for ligand-gated ion channels in rod photoreceptor development.

Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter.

Genomic analysis of mouse retinal development.

Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10.

Methionine adenosyltransferase:adrenergic-cAMP mechanism regulates a daily rhythm in pineal expression.

Synaptogenesis and outer segment formation are perturbed in the neural retina of Crx mutant mice.

The rod photoreceptor pattern is set at the optic vesicle stage and requires spatially restricted cVax expression.

A POU factor binding site upstream of the Chx10 homeobox gene is required for Chx10 expression in subsets of retinal progenitor cells and bipolar cells.

A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.

Retinoic acid regulates the expression of dorsoventral topographic guidance molecules in the chick retina.

Effect of gene expression on cone survival in retinitis pigmentosa.

RCAS-RNAi: a loss-of-function method for the developing chick retina.

Notch 1 inhibits photoreceptor production in the developing mammalian retina.

dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development.

Wnt2b/beta-catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye.

Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property.

Controlled expression of transgenes introduced by in vivo electroporation.

Cellular responses to photoreceptor death in the rd1 mouse model of retinal degeneration.

Automatic correspondence of tags and genes (ACTG): a tool for the analysis of SAGE, MPSS and SBS data.

Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling.

Local retinal circuits of melanopsin-containing ganglion cells identified by transsynaptic viral tracing.

Requirement of histone deacetylase activity for the expression of critical photoreceptor genes.

A typology of photoreceptor gene expression patterns in the mouse.

The cis-regulatory logic of the mammalian photoreceptor transcriptional network.

Temporal order of bipolar cell genesis in the neural retina.

Identification of molecular markers of bipolar cells in the murine retina.

Individual retinal progenitor cells display extensive heterogeneity of gene expression.

Ultrasound-guided in utero injections allow studies of the development and function of the eye.

Analysis of gene function in the retina.

Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration.

Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina.

The transcriptome of retinal Müller glial cells.

A core paired-type and POU homeodomain-containing transcription factor program drives retinal bipolar cell gene expression.

Thyroid hormone components are expressed in three sequential waves during development of the chick retina.

Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons.

Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa.

HDAC4 regulates neuronal survival in normal and diseased retinas.

Identification of genes expressed preferentially in the developing peripheral margin of the optic cup.

Developmental sources of conservation and variation in the evolution of the primate eye.

Development and neurogenic potential of Müller glial cells in the vertebrate retina.

Development and diversification of retinal amacrine interneurons at single cell resolution.

Robust marking of photoreceptor cells and pinealocytes with several reporters under control of the Crx gene.

Alternative splicing produces high levels of noncoding isoforms of bHLH transcription factors during development.

Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.

A common progenitor for retinal astrocytes and oligodendrocytes.

Potent delivery of functional proteins into Mammalian cells in vitro and in vivo using a supercharged protein.

Neuroscience. Seeing the light of day.

Analysis of thyroid response element activity during retinal development.

An isoform-specific SnoN1-FOXO1 repressor complex controls neuronal morphogenesis and positioning in the mammalian brain.

Conditional expression of the TVA receptor allows clonal analysis of descendents from Cre-expressing progenitor cells.

NeuroD factors regulate cell fate and neurite stratification in the developing retina.

A class of human proteins that deliver functional proteins into mammalian cells in vitro and in vivo.

Anterograde or retrograde transsynaptic labeling of CNS neurons with vesicular stomatitis virus vectors.

Restraint of angiogenesis by zinc finger transcription factor CTCF-dependent chromatin insulation.

Identification of a retina-specific Otx2 enhancer element active in immature developing photoreceptors.

Loss of daylight vision in retinal degeneration: are oxidative stress and metabolic dysregulation to blame?

Transcription factor Olig2 defines subpopulations of retinal progenitor cells biased toward specific cell fates.

Emerging gene therapies for retinal degenerations.

Gene expression changes within Müller glial cells in retinitis pigmentosa.