Craig L. Duvall

Quantitative microcomputed tomography analysis of collateral vessel development after ischemic injury.

Impaired angiogenesis, early callus formation, and late stage remodeling in fracture healing of osteopontin-deficient mice.

Host immune competence and local ischemia affects the functionality of engineered vasculature.

The role of osteopontin in recovery from hind limb ischemia.

3D imaging of tissue integration with porous biomaterials.

Development of a novel endosomolytic diblock copolymer for siRNA delivery.

Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice.

Intracellular delivery of a proapoptotic peptide via conjugation to a RAFT synthesized endosomolytic polymer.

Sustained VEGF delivery via PLGA nanoparticles promotes vascular growth.

Intracellular delivery of a protein antigen with an endosomal-releasing polymer enhances CD8 T-cell production and prophylactic vaccine efficacy.

Delivery of intracellular-acting biologics in pro-apoptotic therapies.

RAFT-synthesized graft copolymers that enhance pH-dependent membrane destabilization and protein circulation times.

Sustained local delivery of siRNA from an injectable scaffold.

Poly(PS-b-DMA) micelles for reactive oxygen species triggered drug release.

Intracellular Delivery and Trafficking Dynamics of a Lymphoma-Targeting Antibody-Polymer Conjugate.

Ex vivo optical metabolic measurements from cultured tissue reflect in vivo tissue status.

Macrophage-Specific RNA Interference Targeting via "Click", Mannosylated Polymeric Micelles.

Dual pH- and temperature-responsive microparticles for protein delivery to ischemic tissues.

Nanocarriers for dual delivery of doxorubicin and siRNA to overcome multidrug resistance.

Quantitative optical imaging of vascular response in vivo in a model of peripheral arterial disease.

Balancing cationic and hydrophobic content of PEGylated siRNA polyplexes enhances endosome escape, stability, blood circulation time, and bioactivity in vivo.

Tunable delivery of siRNA from a biodegradable scaffold to promote angiogenesis in vivo.

A porous tissue engineering scaffold selectively degraded by cell-generated reactive oxygen species.

siRNA Delivery from an Injectable Scaffold for Wound Therapy.

In vivo imaging of nanoparticle delivery and tumor microvasculature with multimodal optical coherence tomography.

In situ synthesis of peptide nucleic acids in porous silicon for drug delivery and biosensing.

Matrix Metalloproteinase Responsive, Proximity-activated Polymeric Nanoparticles for siRNA Delivery.

Cell protective, ABC triblock polymer-based thermoresponsive hydrogels with ROS-triggered degradation and drug release.

Future nanomedicine for the diagnosis and treatment of osteoarthritis.

Dual MMP7-proximity-activated and folate receptor-targeted nanoparticles for siRNA delivery.

Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers.

ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease.

Enhanced Performance of Plasmid DNA Polyplexes Stabilized by a Combination of Core Hydrophobicity and Surface PEGylation.

MiRNA inhibition in tissue engineering and regenerative medicine.

Quantifying the vascular response to ischemia with speckle variance optical coherence tomography.

Conjugation of palmitic acid improves potency and longevity of siRNA delivered via endosomolytic polymer nanoparticles.

A transient cell-shielding method for viable MSC delivery within hydrophobic scaffolds polymerized in situ.

Particle-based technologies for osteoarthritis detection and therapy.

Endosomolytic Nano-Polyplex Platform Technology for Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction.

MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia.

Shape-engineered multifunctional porous silicon nanoparticles by direct imprinting.

Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification.

Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification.

Technologies for controlled, local delivery of siRNA.

High conversion of HAuCl4 into gold nanorods: A re-seeding approach.

Hydrolytic charge-reversal of PEGylated polyplexes enhances intracellular un-packaging and activity of siRNA.

Fluorocoxib A loaded nanoparticles enable targeted visualization of cyclooxygenase-2 in inflammation and cancer.

Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing.

Porous Silicon and Polymer Nanocomposites for Delivery of Peptide Nucleic Acids as Anti-MicroRNA Therapies.

Local Delivery of PHD2 siRNA from ROS-Degradable Scaffolds to Promote Diabetic Wound Healing.

Subfailure Overstretch Injury Leads to Reversible Functional Impairment and Purinergic P2X7 Receptor Activation in Intact Vascular Tissue.