Antonello Pileggi

Transduction of human and mouse pancreatic islet cells using a bicistronic recombinant adeno-associated viral vector.

Neonatal porcine pancreatic cell clusters as a potential source for transplantation in humans: characterization of proliferation, apoptosis, xenoantigen expression and gene delivery with recombinant AAV.

Efficient transduction of pancreatic islets by feline immunodeficiency virus vectors1.

Adeno-associated virus transduction of islets with interleukin-4 results in impaired metabolic function in syngeneic marginal islet mass transplantation.

Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice.

Prolonged islet allograft survival in diabetic NOD mice by targeting CD45RB and CD154.

Nonlethal conditioning for the induction of allogeneic chimerism and tolerance to islet allografts.

Heme oxygenase-1 fused to a TAT peptide transduces and protects pancreatic beta-cells.

Long-term islet allograft survival in nonobese diabetic mice treated with tacrolimus, rapamycin, and anti-interleukin-2 antibody.

The effect of simultaneous CD154 and LFA-1 blockade on the survival of allogeneic islet grafts in nonobese diabetic mice.

Adenoviral gene transfer of erythropoietin confers cytoprotection to isolated pancreatic islets.

Targeted bone marrow radioablation with 153Samarium-lexidronam promotes allogeneic hematopoietic chimerism and donor-specific immunologic hyporesponsiveness.

Delivery of Bcl-XL or its BH4 domain by protein transduction inhibits apoptosis in human islets.

Protecting pancreatic beta-cells.

Alterations of the female reproductive system in recipients of islet grafts.

Rescue purification maximizes the use of human islet preparations for transplantation.

Prolonged allogeneic islet graft survival by protoporphyrins.

A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations.

Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience.

Delivery of TAT/PTD-fused proteins/peptides to islets via pancreatic duct.

Systemic overexpression of interleukin-10 fails to protect allogeneic islet transplants in nonobese diabetic mice.

Immunosuppression and procedure-related complications in 26 patients with type 1 diabetes mellitus receiving allogeneic islet cell transplantation.

Reversal of diabetes by pancreatic islet transplantation into a subcutaneous, neovascularized device.

Twenty years of clinical islet transplantation at the Diabetes Research Institute--University of Miami.

Overcoming the challenges now limiting islet transplantation: a sequential, integrated approach.

The l-isoform but not d-isoforms of a JNK inhibitory peptide protects pancreatic beta-cells.

The use of the BD oxygen biosensor system to assess isolated human islets of langerhans: oxygen consumption as a potential measure of islet potency.

Dapsone-induced artifactual a1c reduction in islet transplant recipients.

Resolution of severe atopic dermatitis after tacrolimus withdrawal.

Heme oxygenase-1 upregulation protects against intestinal ischemia/reperfusion injury: a laboratory based study.

Toward maximizing the success rates of human islet isolation: influence of donor and isolation factors.

Allogeneic islet transplantation.

Transplantation: current developments and future directions; the future of clinical islet transplantation as a cure for diabetes.

Quantitative differential expression analysis reveals miR-7 as major islet microRNA.

Allosensitization of islet allograft recipients.

Rapamycin impairs in vivo proliferation of islet beta-cells.

Noninvasive in vivo imaging of pancreatic islet cell biology.

Improved metabolic control and quality of life in seven patients with type 1 diabetes following islet after kidney transplantation.

Exenatide and rare adverse events.

The use of exenatide in islet transplant recipients with chronic allograft dysfunction: safety, efficacy, and metabolic effects.

Restoration of hypoglycemia awareness after islet transplantation.

Riboflavin inhibits IL-6 expression and p38 activation in islet cells.

Characterization of pancreatic ductal cells in human islet preparations.

Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes.

Long-term insulin independence and improvement in insulin secretion after supplemental islet infusion under exenatide and etanercept.

Stable renal function after islet transplantation: importance of patient selection and aggressive clinical management.

Impact of pancreatic cold preservation on rat islet recovery and function.

Point: steady progress and current challenges in clinical islet transplantation.

Nephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release.

Nonalbumin proteinuria in islet transplant recipients.

Long-term metabolic and hormonal effects of exenatide on islet transplant recipients with allograft dysfunction.

Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells.

ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic beta cell.

Prolactin supplementation to culture medium improves beta-cell survival.

Bone marrow-derived stem cell transplantation for the treatment of insulin-dependent diabetes.

Recurrent hypoglycemia exacerbates cerebral ischemic damage in streptozotocin-induced diabetic rats.

Recurrent hypoglycemia increases oxygen glucose deprivation-induced damage in hippocampal organotypic slices.

Recurrence of autoimmunity following pancreas transplantation.

Blockade of leukocyte function antigen-1 (LFA-1) in clinical islet transplantation.

High-resolution, noninvasive longitudinal live imaging of immune responses.

Targeted deletion of one or two copies of the G protein β subunit Gβ5 gene has distinct effects on body weight and behavior in mice.

The thyroid hormone-inactivating type III deiodinase is expressed in mouse and human beta-cells and its targeted inactivation impairs insulin secretion.

Donor islet endothelial cells in pancreatic islet revascularization.

Antisense miR-7 impairs insulin expression in developing pancreas and in cultured pancreatic buds.

Generation of glucose-responsive, insulin-producing cells from human umbilical cord blood-derived mesenchymal stem cells.

Beneficial Effects of Ischemic Preconditioning on Pancreas Cold Preservation.

Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial.

Prevention of autoimmune diabetes and induction of β-cell proliferation in NOD mice by hyperbaric oxygen therapy.

Mesenchymal stem cells for the treatment of diabetes.

Islet Transplantation & β-Cell Replacement Therapies for Diabetes.

Inflammation-Mediated Regulation of MicroRNA Expression in Transplanted Pancreatic Islets.

Intracardial embryonic delivery of developmental modifiers in utero.

Macroporous Three Dimensional PDMS Scaffolds for Extrahepatic Islet Transplantation.

Noninvasive in vivo model demonstrating the effects of autonomic innervation on pancreatic islet function.

Long-Term Heart Transplant Survival by Targeting the Ionotropic Purinergic Receptor P2X7.