Helen M. Arthur

Institute of Genetic Medicine, Newcastle University

Research Area

Neuroscience

Biography

Helen M. Arthur has not added Biography.
If you are Helen M. Arthur and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

Article Total : 1	Year
Publication title	2013

Other Publications

Article	Year
Endoglin expression in early development is associated with vasculogenesis and angiogenesis. Mechanisms of development\| PubMed ID: 11744382	2002
Mouse model for hereditary hemorrhagic telangiectasia has a generalized vascular abnormality. Circulation\| PubMed ID: 12668501	2003
Vascular endothelial growth factor induces abnormal microvasculature in the endoglin heterozygous mouse brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 14747750	2004
Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction. The EMBO journal\| PubMed ID: 15385967	2004
Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia. Development (Cambridge, England)\| PubMed ID: 15548578	2004
A direct interaction between TGFbeta activated kinase 1 and the TGFbeta type II receptor: implications for TGFbeta signalling and cardiac hypertrophy. Cardiovascular research\| PubMed ID: 16360132	2006
Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox-independent mechanism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17012253	2006
Endoglin has a crucial role in blood cell-mediated vascular repair. Circulation\| PubMed ID: 17088457	2006
Generation of a floxed allele of the mouse Endoglin gene. Genesis (New York, N.Y. : 2000)\| PubMed ID: 17506087	2007
Extracellular control of TGFbeta signalling in vascular development and disease. Nature reviews. Molecular cell biology\| PubMed ID: 17895899	2007
Circulating endothelial progenitor cells exhibit diurnal variation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 18296584	2008
Endoglin and activin receptor-like-kinase 1 are co-expressed in the distal vessels of the lung: implications for two familial vascular dysplasias, HHT and PAH. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 19015642	2009
Pathogenesis of arteriovenous malformations in the absence of endoglin. Circulation research\| PubMed ID: 20224041	2010
Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia. Nature medicine\| PubMed ID: 20364125	2010
The TGFÎ² type II receptor plays a critical role in the endothelial cells during cardiac development. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 20652948	2010
The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro. In vitro cellular & developmental biology. Animal\| PubMed ID: 21082279	2011
TGFÎ² signaling and congenital heart disease: Insights from mouse studies. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 21538815	2011
Angiotensin II-induced cardiomyocyte hypertrophy in vitro is TAK1-dependent and Smad2/3-independent. Hypertension research : official journal of the Japanese Society of Hypertension\| PubMed ID: 22072105	2012
Angiogenesis regulation by TGFÎ² signalling: clues from an inherited vascular disease. Biochemical Society transactions\| PubMed ID: 22103504	2011
Non-synonymous variants in the SMAD6 gene predispose to congenital cardiovascular malformation. Human mutation\| PubMed ID: 22275001	2012
Minimal homozygous endothelial deletion of Eng with VEGF stimulation is sufficient to cause cerebrovascular dysplasia in the adult mouse. Cerebrovascular diseases (Basel, Switzerland)\| PubMed ID: 22571958	2012
Endothelial expression of TGFÎ² type II receptor is required to maintain vascular integrity during postnatal development of the central nervous system. PloS one\| PubMed ID: 22745736	2012
Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination. The Journal of experimental medicine\| PubMed ID: 23401487	2013
The tissue-specific RNA binding protein T-STAR controls regional splicing patterns of neurexin pre-mRNAs in the brain. PLoS genetics\| PubMed ID: 23637638	2013