Alfred E. Chang

A phase I trial of tumor lysate-pulsed dendritic cells in the treatment of advanced cancer.

Resection of liver tumors: technical aspects.

Mammographic screening of TRAM flap breast reconstructions for detection of nonpalpable recurrent cancer.

Therapeutic effects of tumor reactive CD4+ cells generated from tumor-primed lymph nodes using anti-CD3/anti-CD28 monoclonal antibodies.

Hepatic artery chemotherapy for colorectal liver metastases: technical considerations and review of clinical trials.

Melanoma and human leukocyte antigen status: the missing link?

Applications of gene transfer to cellular immunotherapy.

Generation of vaccine-primed lymphocytes for the treatment of head and neck cancer.

Phase II trial of autologous tumor vaccination, anti-CD3-activated vaccine-primed lymphocytes, and interleukin-2 in stage IV renal cell cancer.

Polarization effects of 4-1BB during CD28 costimulation in generating tumor-reactive T cells for cancer immunotherapy.

Antitumor reactivity of anti-CD3/anti-CD28 bead-activated lymphoid cells: implications for cell therapy in a murine model.

Sentinel node biopsy prior to neoadjuvant chemotherapy.

Comparison of attenuation-corrected and non-corrected FDG-PET images for axillary nodal staging in newly diagnosed breast cancer.

Clinicopathologic features of metastasis in nonsentinel lymph nodes of breast carcinoma patients.

Radiotherapy potentiates the therapeutic efficacy of intratumoral dendritic cell administration.

Intratumoral IL-12 and TNF-alpha-loaded microspheres lead to regression of breast cancer and systemic antitumor immunity.

Exaggerated pigmented granulomatous reaction to the artificial joint implant mimics metastatic melanoma.

Mitotic rate and younger age are predictors of sentinel lymph node positivity: lessons learned from the generation of a probabilistic model.

Donor cell cycling, trafficking, and accumulation during adoptive immunotherapy for murine lung metastases.

Efficacy of sentinel lymph node biopsy in male breast cancer.

Mastectomy and concomitant sentinel lymph node biopsy for invasive breast cancer.

An academic health center cost analysis of screening mammography: creating a financially viable service.

Anti-CD137 monoclonal antibody administration augments the antitumor efficacy of dendritic cell-based vaccines.

Synergistic effects of IL-12 and IL-18 in skewing tumor-reactive T-cell responses towards a type 1 pattern.

Immunologic response to cryoablation of breast cancer.

Predictors of nonsentinel lymph node positivity in patients with a positive sentinel node for melanoma.

Capecitabine and radiation therapy preceded and followed by combination chemotherapy in advanced pancreatic cancer.

Simultaneous targeting of CD3 on T cells and CD40 on B or dendritic cells augments the antitumor reactivity of tumor-primed lymph node cells.

Is blue dye indicated for sentinel lymph node biopsy in breast cancer patients with a positive lymphoscintigram?

Comprehensive axillary evaluation in neoadjuvant chemotherapy patients with ultrasonography and sentinel lymph node biopsy.

Wide excision without radiation for desmoplastic melanoma.

Lymphatic mapping and sentinel lymph node biopsy for patients with local recurrence after breast-conservation therapy.

Clinicopathologic features associated with having four or more metastatic axillary nodes in breast cancer patients with a positive sentinel lymph node.

Does the method of biopsy affect the incidence of sentinel lymph node metastases?

Ex vivo culture with interleukin (IL)-12 improves CD8(+) T-cell adoptive immunotherapy for murine leukemia independent of IL-18 or IFN-gamma but requires perforin.

Significance of multiple lymphatic basin drainage in truncal melanoma patients undergoing sentinel lymph node biopsy.

Neoadjuvant intratumoral cytokine-loaded microspheres are superior to postoperative autologous cellular vaccines in generating systemic anti-tumor immunity.

Adoptive immunotherapy of breast cancer with lymph node cells primed by cryoablation of the primary tumor.

Changes in surgical management resulting from case review at a breast cancer multidisciplinary tumor board.

CXC chemokine ligand 13 and CC chemokine ligand 19 cooperatively render resistance to apoptosis in B cell lineage acute and chronic lymphocytic leukemia CD23+CD5+ B cells.

The impact of factors beyond Breslow depth on predicting sentinel lymph node positivity in melanoma.

Improving surgical outcomes for cancer in the United States.

What is a sentinel node? Re-evaluating the 10% rule for sentinel lymph node biopsy in melanoma.

Radiation-induced apoptosis along with local and systemic cytokine elaboration is associated with DC plus radiotherapy-mediated renal cell tumor regression.

4-1BB costimulation of effector T cells for adoptive immunotherapy of cancer: involvement of Bcl gene family members.

Sentinel lymph node biopsy performed after neoadjuvant chemotherapy is accurate in patients with documented node-positive breast cancer at presentation.

Inguinal node dissection for melanoma in the era of sentinel lymph node biopsy.

Sentinel lymph node biopsy for breast cancer: how many nodes are enough?

CCL19 and CXCL13 synergistically regulate interaction between B cell acute lymphocytic leukemia CD23+CD5+ B Cells and CD8+ T cells.

Phase I study of oxaliplatin, full-dose gemcitabine, and concurrent radiation therapy in pancreatic cancer.

The registry case finding engine: an automated tool to identify cancer cases from unstructured, free-text pathology reports and clinical notes.

Synergistic effect of intratumoral IL-12 and TNF-alpha microspheres: systemic anti-tumor immunity is mediated by both CD8+ CTL and NK cells.

Generation of a tumor-specific systemic response after intratumoral injection of IL-12 and IL-18-loaded polylactic acid microspheres.

Adjuvant effect of anti-4-1BB mAb administration in adoptive T cell therapy of cancer.

Mechanisms involved in radiation enhancement of intratumoral dendritic cell therapy.

Interleukin-21 augments the efficacy of T-cell therapy by eliciting concurrent cellular and humoral responses.

Phase Ib trial assessing autologous, tumor-pulsed dendritic cells as a vaccine administered with or without IL-2 in patients with metastatic melanoma.

Tumor-induced immune suppression of in vivo effector T-cell priming is mediated by the B7-H1/PD-1 axis and transforming growth factor beta.

Do micromorphometric features of metastatic deposits within sentinel nodes predict nonsentinel lymph node involvement in melanoma?

Axillary staging prior to neoadjuvant chemotherapy for breast cancer: predictors of recurrence.

Intratumoral dendritic cells and chemoradiation for the treatment of murine squamous cell carcinoma.

Dendritic cells pulsed with keyhole limpet hemocyanin and cryopreserved maintain anti-tumor activity in a murine melanoma model.

Residual disease after re-excision lumpectomy for close margins.

Determinants of breast conservation rates: reasons for mastectomy at a comprehensive cancer center.

Antitumor activity of T cells generated from lymph nodes draining the SEA-expressing murine B16 melanoma and secondarily activated with dendritic cells.

Gemcitabine-based combination chemotherapy followed by radiation with capecitabine as adjuvant therapy for resected pancreas cancer.

Radiotherapy combined with intratumoral dendritic cell vaccination enhances the therapeutic efficacy of adoptive T-cell transfer.

In vivo sensitized and in vitro activated B cells mediate tumor regression in cancer adoptive immunotherapy.

Prognostic significance of a positive nonsentinel lymph node in cutaneous melanoma.

Intratumoral delivery of encapsulated IL-12, IL-18 and TNF-alpha in a model of metastatic breast cancer.

Is there a benefit to sentinel lymph node biopsy in patients with T4 melanoma?

Rate of freeze alters the immunologic response after cryoablation of breast cancer.

From the guest editors: introduction to local therapies in the treatment of liver cancer.

Intratumoral expression of IL-17 and its prognostic role in gastric adenocarcinoma patients.

Surgical options for localized and advanced gastrointestinal stromal tumors.

Adoptive transfer of tumor reactive B cells confers host T-cell immunity and tumor regression.

Long-term cultured human neural stem cells undergo spontaneous transformation to tumor-initiating cells.

Validation of statistical predictive models meant to select melanoma patients for sentinel lymph node biopsy.

Is a level III dissection necessary for a positive sentinel lymph node in melanoma?

B lymphocytes as effector cells in the immunotherapy of cancer.

Defining the critical hurdles in cancer immunotherapy.

Is duct excision still necessary for all cases of suspicious nipple discharge?

Characterization of bridging integrator 1 (BIN1) as a potential tumor suppressor and prognostic marker in hepatocellular carcinoma.

Cancer stem cell vaccination confers significant antitumor immunity.

Interleukin-6 inhibits regulatory T cells and improves the proliferation and cytotoxic activity of cytokine-induced killer cells.

Targeting cancer stem cells via dendritic-cell vaccination.

Effects of tumor irradiation on host T-regulatory cells and systemic immunity in the context of adoptive T-cell therapy in mice.

Cytokine-induced killer (CIK) cells bound with anti-CD3/anti-CD133 bispecific antibodies target CD133(high) cancer stem cells in vitro and in vivo.

IL-17A promotes immune cell recruitment in human esophageal cancers and the infiltrating dendritic cells represent a positive prognostic marker for patient survival.

Cancer immunotherapy: current status and future directions.

OK-432 synergizes with IFN-γ to confer dendritic cells with enhanced antitumor immunity.