Dirk E. Martens

Metabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysis.

Pivotal role of the non-hr origin of DNA replication in the genesis of defective interfering baculoviruses.

Cartilage tissue engineering: controversy in the effect of oxygen.

Evaluation of baculovirus expression vectors with enhanced stability in continuous cascaded insect-cell bioreactors.

Effect of feed and bleed rate on hybridoma cells in an acoustic perfusion bioreactor: part I. Cell density, viability, and cell-cycle distribution.

Stable hybridoma cultivation in a pilot-scale acoustic perfusion system: long-term process performance and effect of recirculation rate.

Application of a continuous bioreactor cascade to study the effect of linoleic acid on hybridoma cell physiology.

PAT for vaccines: the first stage of PAT implementation for development of a well-defined whole-cell vaccine against whooping cough disease.

Effect of feed and bleed rate on hybridoma cells in an acoustic perfusion bioreactor: metabolic analysis.

Modeling Neisseria meningitidis metabolism: from genome to metabolic fluxes.

Scale-up for bulk production of vaccine against meningococcal disease.

Evaluation of a critical process parameter: oxygen limitation during cultivation has a fully reversible effect on gene expression of Bordetella pertussis.

Modeling Neisseria meningitidis B metabolism at different specific growth rates.

Expression of phosphofructokinase in Neisseria meningitidis.

Photosynthetic efficiency of Chlorella sorokiniana in a turbulently mixed short light-path photobioreactor.

Cell cycle analysis of primary sponge cell cultures.

Effect of O₂:CO₂ ratio on the primary metabolism of Chlamydomonas reinhardtii.

Genome-scale metabolic models: reconstruction and analysis.

Light respiration in Chlorella sorokiniana.

Metabolic modeling of Chlamydomonas reinhardtii: energy requirements for photoautotrophic growth and maintenance.

Cultivation of sponges, sponge cells and symbionts: achievements and future prospects.

The impact of nitrogen starvation on the dynamics of triacylglycerol accumulation in nine microalgae strains.

Simultaneous growth and neutral lipid accumulation in microalgae.

Effect of light intensity, pH, and temperature on triacylglycerol (TAG) accumulation induced by nitrogen starvation in Scenedesmus obliquus.

A model for customising biomass composition in continuous microalgae production.

Genome-scale metabolic model for Lactococcus lactis MG1363 and its application to the analysis of flavor formation.

Configuration of bioreactors.

Superior triacylglycerol (TAG) accumulation in starchless mutants of Scenedesmus obliquus: (II) evaluation of TAG yield and productivity in controlled photobioreactors.

Glucose gradients influence zonal matrix deposition in 3D cartilage constructs.

Superior triacylglycerol (TAG) accumulation in starchless mutants of Scenedesmus obliquus: (I) mutant generation and characterization.

Circadian rhythms in the cell cycle and biomass composition of Neochloris oleoabundans under nitrogen limitation.

Dynamics of biomass composition and growth during recovery of nitrogen-starved Chromochloris zofingiensis.

Opportunities to improve the areal oil productivity of microalgae.