Teresa Brooks

Novel inhibitors of plasminogen activator inhibitor-1: development of new templates from diketopiperazines.

Plasminogen activator inhibitor-1 supports IL-8-mediated neutrophil transendothelial migration by inhibition of the constitutive shedding of endothelial IL-8/heparan sulfate/syndecan-1 complexes.

XR5967, a novel modulator of plasminogen activator inhibitor-1 activity, suppresses tumor cell invasion and angiogenesis in vitro.

Detection and identification of Legionella species from groundwaters.

Discovery of a novel class of selective human CB1 inverse agonists.

Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas.

Discovery and functional evaluation of diverse novel human CB(1) receptor ligands.

Discovery and optimization of potent and selective functional antagonists of the human adenosine A2B receptor.

Vibrio cholerae requires the type VI secretion system virulence factor VasX to kill Dictyostelium discoideum.

VasH is a transcriptional regulator of the type VI secretion system functional in endemic and pandemic Vibrio cholerae.

Fatty acid amide hydrolase inhibitors. 3: tetra-substituted azetidine ureas with in vivo activity.

Constitutive type VI secretion system expression gives Vibrio cholerae intra- and interspecific competitive advantages.

Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling.

Lytic activity of the Vibrio cholerae type VI secretion toxin VgrG-3 is inhibited by the antitoxin TsaB.