Eric Brown

Structures of the multicomponent Rieske non-heme iron toluene 2,3-dioxygenase enzyme system.

Aberrant Epstein-Barr viral infection in systemic lupus erythematosus.

Polar localization of virulence-related Esx-1 secretion in mycobacteria.

Temporal variability in chlorophyll fluorescence of back-reef corals in Ofu, American Samoa.

Labeling TiO2 nanoparticles with dyes for optical fluorescence microscopy and determination of TiO2-DNA nanoconjugate stability.

The ATPase activity of an 'essential' Bacillus subtilis enzyme, YdiB, is required for its cellular function and is modulated by oligomerization.

Drug discovery: Not as fab as we thought.

QTAIM study on the degenerate cope rearrangements of 1,5-hexadiene and semibullvalene.

Cell biology. The art of making an exit.

Coliform and Escherichia coli contamination of desserts served in public restaurants from Guadalajara, Mexico, and Houston, Texas.

High-throughput screening of model bacteria.

High-throughput screening identifies novel inhibitors of the acetyltransferase activity of Escherichia coli GlmU.

The N-acetylmannosamine transferase catalyzes the first committed step of teichoic acid assembly in Bacillus subtilis and Staphylococcus aureus.

Detection of live Salmonella sp. cells in produce by a TaqMan-based quantitative reverse transcriptase real-time PCR targeting invA mRNA.

Ubiquilins accelerate autophagosome maturation and promote cell survival during nutrient starvation.

Atg5-independent sequestration of ubiquitinated mycobacteria.

Probing teichoic acid genetics with bioactive molecules reveals new interactions among diverse processes in bacterial cell wall biogenesis.

Design and analysis of the Community Youth Development Study longitudinal cohort sample.

The wall teichoic acid polymerase TagF is non-processive in vitro and amenable to study using steady state kinetic analysis.

Phylogenetic evidence for extensive horizontal gene transfer of type III secretion system genes among enterobacterial plant pathogens.

New screens and targets in antibacterial drug discovery.

HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses.

Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53.

Results of a type 2 translational research trial to prevent adolescent drug use and delinquency: a test of Communities That Care.

Are essential genes really essential?

Phase I/II study evaluating early tolerance in breast cancer patients undergoing accelerated partial breast irradiation treated with the mammosite balloon breast brachytherapy catheter using a 2-day dose schedule.

Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting.

Dynamic jamming point for shear thickening suspensions.

Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis.

Pretreatment of epithelial cells with rifaximin alters bacterial attachment and internalization profiles.

Systematic genetic nomenclature for type VII secretion systems.

In vivo bioimaging tracks conditionally replicative adenoviral replication and provides an early indication of viral antitumor efficacy.

Microbial etiology of travelers' diarrhea in Mexico, Guatemala, and India: importance of enterotoxigenic Bacteroides fragilis and Arcobacter species.

Generality of shear thickening in dense suspensions.

Cytosol as battleground: ubiquitin as a weapon for both host and pathogen.

Protein tyrosine phosphatase SHP-1 positively regulates TLR-induced IL-12p40 production in macrophages through inhibition of phosphatidylinositol 3-kinase.

The Panton-Valentine leukocidin is a virulence factor in a murine model of necrotizing pneumonia.

The actin-bundling protein L-plastin dissociates CCR7 proximal signaling from CCR7-induced motility.

Complement, age-related macular degeneration and a vision of the future.

Removing all obstacles: a critical role for p53 in promoting tissue renewal.

PCR-based method for targeting 16S-23S rRNA intergenic spacer regions among Vibrio species.

A high-throughput pharmacoviral approach identifies novel oncolytic virus sensitizers.

Structure of the bacterial teichoic acid polymerase TagF provides insights into membrane association and catalysis.

Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection.

Development of a method for effective amplification of human adenovirus 40.

Development of an improved protocol for the isolation and detection of Enterobacter sakazakii (Cronobacter) from powdered infant formula.

An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase.

Population dynamics of Vibrio spp. associated with marine sponge microcosms.

Chemical genomic approaches to study model microbes.

Using a riboswitch sensor to examine coenzyme B(12) metabolism and transport in E. coli.

Chemical probes of Escherichia coli uncovered through chemical-chemical interaction profiling with compounds of known biological activity.

Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint.

Surgical management of calciphylaxis associated with primary hyperparathyroidism: a case report and review of the literature.

Endocytosis of titanium dioxide nanoparticles in prostate cancer PC-3M cells.

Compensatory insulin receptor (IR) activation on inhibition of insulin-like growth factor-1 receptor (IGF-1R): rationale for cotargeting IGF-1R and IR in cancer.

Evaluation of the taxonomic utility of six-enzyme pulsed-field gel electrophoresis in reconstructing Salmonella subspecies phylogeny.

Phylogenetic evaluation of the 'Typhimurium' complex of Salmonella strains using a seven-gene multi-locus sequence analysis.

Simultaneous analysis of multiple enzymes increases accuracy of pulsed-field gel electrophoresis in assigning genetic relationships among homogeneous Salmonella strains.

Actin-bundling protein L-plastin regulates T cell activation.

Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase.

Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner.

Prevalence and risk factors of methicillin-resistant Staphylococcus aureus colonization among critically ill hospitalized patients in a tertiary care center in Houston, Texas: an active surveillance pilot project.

Selective deletion of a cell cycle checkpoint kinase (ATR) reduces neurogenesis and alters responses in rodent models of behavioral affect.

Understanding ribosome assembly: the structure of in vivo assembled immature 30S subunits revealed by cryo-electron microscopy.

Identification of a salmonellosis outbreak by means of molecular sequencing.

Conditional deletion of SLP-76 in mature T cells abrogates peripheral immune responses.

Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy.

Studies of the genetics, function, and kinetic mechanism of TagE, the wall teichoic acid glycosyltransferase in Bacillus subtilis 168.

Effects of fluorescent dye coating of metal oxide nanoparticles on DNA scission.

Antibiotics as probes of biological complexity.

Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole.

A delicate dance: host response to mycobacteria.

Four-year results using balloon-based brachytherapy to deliver accelerated partial breast irradiation with a 2-day dose fractionation schedule.

Intraoperative waste in spine surgery: incidence, cost, and effectiveness of an educational program.

Comparison of real-time PCR, reverse transcriptase real-time PCR, loop-mediated isothermal amplification, and the FDA conventional microbiological method for the detection of Salmonella spp. in produce.

Differential gene expression by RamA in ciprofloxacin-resistant Salmonella Typhimurium.

Single nucleotide polymorphism (SNP)-based differentiation of Shigella isolates by pyrosequencing.

Impaired FcεRI stability, signaling, and effector functions in murine mast cells lacking glycosylphosphatidylinositol-anchored proteins.

Materials science. Through thick and thin.

Total synthesis and repudiation of the helianane family.

Vibrio caribbeanicus sp. nov., isolated from the marine sponge Scleritoderma cyanea.

Optical-optical double resonance spectroscopy of the quasi-linear S2 state of CHF and CDF. II. Predissociation and mode-specific dynamics.

Cryo-electron microscopy structure of the 30S subunit in complex with the YjeQ biogenesis factor.

Sustained decreases in risk exposure and youth problem behaviors after installation of the Communities That Care prevention system in a randomized trial.

Emergency Cricothyrotomy in Confined Space Airway Emergencies: A Comparison.

Shear thickening and jamming in densely packed suspensions of different particle shapes.

Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR.

Demographics, socio-behavioral factors, and drug use patterns: what matters in spontaneous HCV clearance?

Genotype-based changes in serum uric acid affect blood pressure.

Implementation of the Communities That Care Prevention System by Coalitions in the Community Youth Development Study.

Genetic characterization of Escherichia coli O104 isolates from different sources in the United States.

Dye surface coating enables visible light activation of TiO2 nanoparticles leading to degradation of neighboring biological structures.

Implications of the WHO Child Growth Standards in rural Honduras.

High resolution clustering of Salmonella enterica serovar Montevideo strains using a next-generation sequencing approach.

ATR maintains select progenitors during nervous system development.

Methicillin Resistance Reduces the Virulence of Healthcare-Associated Methicillin-Resistant Staphylococcus aureus by Interfering With the agr Quorum Sensing System.

Constitutive production of catalytic antibodies to a Staphylococcus aureus virulence factor and effect of infection.

Demonstration of the weighted-incidence syndromic combination antibiogram: an empiric prescribing decision aid.

EccA1, a component of the Mycobacterium marinum ESX-1 protein virulence factor secretion pathway, regulates mycolic acid lipid synthesis.

Chk'ing p53-deficient breast cancers.

Strain stiffening in random packings of entangled granular chains.

Delivery of interferon alpha using a novel Cox2-controlled adenovirus for pancreatic cancer therapy.

Use of integrated landscape indicators to evaluate the health of linked watersheds and coral reef environments in the Hawaiian islands.

Ubiquilins in the crosstalk among proteolytic pathways.

Genome sequences of five Salmonella enterica serovar Heidelberg isolates associated with a 2011 multistate outbreak in the United States.

Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells.

Bacterial identification and subtyping using DNA microarray and DNA sequencing.

Intramolecular condensation via an o-quinone methide: total synthesis of (±)-heliol.

Evaluation of a revised U.S. Food and Drug Administration method for the detection of Cronobacter in powdered infant formula: a collaborative study.

Sustained effects of the Communities That Care system on prevention service system transformation.

High-throughput multimodal strong anion exchange purification and N-glycan characterization of endogenous glycoprotein expressed in glycoengineered Pichia pastoris.

Generation of a novel, cyclooxygenase-2-targeted, interferon-expressing, conditionally replicative adenovirus for pancreatic cancer therapy.

Impaired function of antibodies to pneumococcal surface protein A but not to capsular polysaccharide in Mexican American adults with type 2 diabetes mellitus.

Using metagenomic analyses to estimate the consequences of enrichment bias for pathogen detection.

Mycobacterium marinum SecA2 promotes stable granulomas and induces tumor necrosis factor alpha in vivo.

Staphylococcus aureus extracellular adherence protein triggers TNFα release, promoting attachment to endothelial cells via protein A.

Draft genome sequences of eight Salmonella enterica serotype newport strains from diverse hosts and locations.

Interplay between the Westerlies and Asian monsoon recorded in Lake Qinghai sediments since 32 ka.

Guidelines for the use and interpretation of assays for monitoring autophagy.

Surface modification of the TiO2 nanoparticle surface enables fluorescence monitoring of aggregation and enhanced photoreactivity.

Spectroscopy and dynamics of the predissociated, quasi-linear S2 state of chlorocarbene.

High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples.

Infectivity-selective oncolytic adenovirus developed by high-throughput screening of adenovirus-formatted library.

Draft genome sequences of 21 Salmonella enterica serovar enteritidis strains.

Phylogenetic analysis of non-O157 Shiga toxin-producing Escherichia coli strains by whole-genome sequencing.

Inhibition of WTA synthesis blocks the cooperative action of PBPs and sensitizes MRSA to β-lactams.

Integrating genome-based informatics to modernize global disease monitoring, information sharing, and response.

Proteomic analysis of vitreous biopsy techniques.

Characterization of microflora in Latin-style cheeses by next-generation sequencing technology.

Predictive validity of established cut points for risk and protective factor scales from the communities that care youth survey.

Differentially regulated gene expression associated with hepatitis C virus clearance.

Novel epidemic clones of Listeria monocytogenes, United States, 2011.

RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle.

Colonization and internalization of Salmonella enterica in tomato plants.

On the evolutionary history, population genetics and diversity among isolates of Salmonella Enteritidis PFGE pattern JEGX01.0004.

Discovery of antibiotic adjuvants.

Genome Sequences of Salmonella enterica Serovar Heidelberg Isolates Isolated in the United States from a Multistate Outbreak of Human Salmonella Infections.

Phylogenetics and differentiation of Salmonella Newport lineages by whole genome sequencing.

Draft Genome Sequence of a Clostridium botulinum Isolate from Water Used for Cooling at a Plant Producing Low-Acid Canned Foods.

Analysis of pulsed field gel electrophoresis profiles using multiple enzymes for predicting potential source reservoirs for strains of Salmonella Enteritidis and Salmonella Typhimurium isolated from humans.

Engagement Matters: Lessons from Assessing Classroom Implementation of Steps to Respect: A Bullying Prevention Program Over a One-year Period.

Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery.

Draft Genome Sequences of Three Salmonella enterica Serotype Agona Strains from China.

Degradation of MAC13243 and studies of the interaction of resulting thiourea compounds with the lipoprotein targeting chaperone LolA.

Fully Assembled Genome Sequence for Salmonella enterica subsp. enterica Serovar Javiana CFSAN001992.

Molecular Serogrouping of Shiga Toxin-Producing Escherichia coli Using Suspension Array.

Development of a Cell-Based Functional Assay for the Detection of Clostridium botulinum Neurotoxin Types A and E.

Is the GAIN Act a turning point in new antibiotic discovery?

A high-throughput screen of the GTPase activity of Escherichia coli EngA to find an inhibitor of bacterial ribosome biogenesis.

Prevention Service System Transformation Using Communities That Care.

Advancements in using TiO2 bionanoconjugates for precision degradation of intracellular biological structures.

The impact of a middle school program to reduce aggression, victimization, and sexual violence.

Whole-Genome Sequences of Four Salmonella enterica Serotype Newport Strains from Humans.

N-terminal helix-cap in α-helix 2 modulates β-state misfolding in rabbit and hamster prion proteins.

Impact dynamics of oxidized liquid metal drops.

Genome Sequences of Two Emerging Non-O157 Shiga Toxin-Producing Escherichia coli Strains.

Baseline survey of the anatomical microbial ecology of an important food plant: Solanum lycopersicum (tomato).

The role of the immune system in governing host-microbe interactions in the intestine.

ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing.

Prevention System Mediation of Communities That Care Effects on Youth Outcomes.

What is in a name? Oral and maxillofacial surgeon versus oral surgeon.

Child physical and sexual abuse and cigarette smoking in adolescence and adulthood.

Chocolate habits of Nobel prizewinners.

Therapist responsiveness and patient engagement in therapy.

Rifaximin-mediated changes to the epithelial cell proteome: 2-D gel analysis.

Impaired CD4+ and T-helper 17 cell memory response to Streptococcus pneumoniae is associated with elevated glucose and percent glycated hemoglobin A1c in Mexican Americans with type 2 diabetes mellitus.

Collapsing the proton motive force to identify synergistic combinations against Staphylococcus aureus.

Draft Genome Sequences of Paenibacillus alvei A6-6i and TS-15.

Co-enriching microflora associated with culture based methods to detect Salmonella from tomato phyllosphere.

Tests of the mitigating effects of caring and supportive relationships in the study of abusive disciplining over two generations.

Draft Genome Sequences of Two O104:H21 Escherichia coli Isolates Causing Hemorrhagic Colitis during a 1994 Montana Outbreak Provide Insight into Their Pathogenicity.

Draft Genome Sequences of Two Salmonella Strains from the SARA Collection, SARA64 (Muenchen) and SARA33 (Heidelberg), Provide Insight into Their Antibiotic Resistance.

Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation.

Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins.

Instructional design affects the efficacy of simulation-based training in central venous catheterization.

RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells.

Phylogenetic diversity of the enteric pathogen Salmonella enterica subsp. enterica inferred from genome-wide reference-free SNP characters.

Taking aim at wall teichoic acid synthesis: new biology and new leads for antibiotics.

Management of acute cholecystitis: prevalence of percutaneous cholecystostomy and delayed cholecystectomy in the elderly.

Phylogenomic analysis identifies gene gains that define Salmonella enterica subspecies I.

A fresh look at the hygiene hypothesis: how intestinal microbial exposure drives immune effector responses in atopic disease.

Comparison of a novel strategy for the detection and isolation of Salmonella in shell eggs with the Food and Drug Administration Bacteriological Analytical Manual method.

Bile salt inhibition of host cell damage by Clostridium difficile toxins.

Antibiotic resistance-the need for global solutions.

Clinical significance of methicillin-resistant Staphylococcus aureus colonization on hospital admission: one-year infection risk.

Identifying Potential Therapeutic Targets of Methicillin-resistant Staphylococcus aureus Through in Vivo Proteomic Analysis.

Global Gene Expression of Methicillin-resistant Staphylococcus aureus USA300 During Human and Mouse Infection.

Exploring intermolecular interactions of a substrate binding protein using a riboswitch-based sensor.

Variation in the Effect of Communities That Care on Community Adoption of a Scientific Approach to Prevention.

Youth problem behaviors 8 years after implementing the communities that care prevention system: a community-randomized trial.

Association of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Elements with Specific Serotypes and Virulence Potential of Shiga Toxin-Producing Escherichia coli.

Complete Genome Sequence of a Multidrug-Resistant Salmonella enterica Serovar Typhimurium var. 5- Strain Isolated from Chicken Breast.

Metal-induced isomerization yields an intracellular chelator that disrupts bacterial iron homeostasis.

Designing analogs of ticlopidine, a wall teichoic acid inhibitor, to avoid formation of its oxidative metabolites.

Erratum: The role of the immune system in governing host-microbe interactions in the intestine.

Stool substitute transplant therapy for the eradication of Clostridium difficile infection: 'RePOOPulating' the gut.

Wild-Type RAS: Keeping Mutant RAS in CHK.

Genetic Diversity and Evolution of the Salmonella Enteritidis Strains with Different Phage Types.

NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion.

Quantitative Genome-Wide Genetic Interaction Screens Reveal Global Epistatic Relationships of Protein Complexes in Escherichia coli.