Fen Xia

The molecular basis of radiosensitivity and chemosensitivity in the treatment of breast cancer.

Recombinational DNA Repair in Cancer and Normal Cells: The Challenge of Functional Analysis.

BRCA2 keeps Rad51 in line. High-fidelity homologous recombination prevents breast and ovarian cancer?

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.

DNA damage induces p53-dependent BRCA1 nuclear export.

Checkpoint kinase 2-mediated phosphorylation of BRCA1 regulates the fidelity of nonhomologous end-joining.

The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response.

Erlotinib attenuates homologous recombinational repair of chromosomal breaks in human breast cancer cells.

Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice.

Exonuclease function of human Mre11 promotes deletional nonhomologous end joining.

Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair.

BRCA1 16 years later: DNA damage-induced BRCA1 shuttling.

DNA damage-induced cytotoxicity is dissociated from BRCA1's DNA repair function but is dependent on its cytosolic accumulation.

Hdac3 is essential for the maintenance of chromatin structure and genome stability.

Delayed cerebral radiation necrosis following treatment for a plasmacytoma of the skull.

Glycogen synthase kinase 3beta inhibition enhances repair of DNA double-strand breaks in irradiated hippocampal neurons.

p53-dependent BRCA1 nuclear export controls cellular susceptibility to DNA damage.

Targeting BRCA1 Localization to Augment Breast Tumor Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition.