Howard D. White

Observation of transient disorder during myosin subfragment-1 binding to actin by stopped-flow fluorescence and millisecond time resolution electron cryomicroscopy: evidence that the start of the crossbridge power stroke in muscle has variable geometry.

Mechanism of regulation of phosphate dissociation from actomyosin-ADP-Pi by thin filament proteins.

The prepower stroke conformation of myosin V.

Kinetic mechanism of myosinV-S1 using a new fluorescent ATP analogue.

Real-time measurement of myosin-nucleotide noncovalent complexes by electrospray ionization mass spectrometry.

Kinetics of ADP dissociation from the trail and lead heads of actomyosin V following the power stroke.

Smooth muscle myosin phosphorylated at single head shows sustained mechanical activity.

Direct observation of the mechanochemical coupling in myosin Va during processive movement.

Switch 1 mutation S217A converts myosin V into a low duty ratio motor.

The SAH domain extends the functional length of the myosin lever.

Mechanism of regulation of native cardiac muscle thin filaments by rigor cardiac myosin-S1 and calcium.

Regulation of actin-myosin interaction by conserved periodic sites of tropomyosin.

Coupling of two non-processive myosin 5c dimers enables processive stepping along actin filaments.

Modulation of thin filament activation of myosin ATP hydrolysis by N-terminal domains of cardiac myosin binding protein-C.

Omecamtiv Mecarbil modulates the kinetic and motile properties of porcine β-cardiac myosin.

C0 and C1 N-terminal Ig domains of myosin binding protein C exert different effects on thin filament activation.

Ca-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy.

The shaker-1 mouse myosin VIIa deafness mutation results in a severely reduced rate of the ATP hydrolysis step.

Distinct sites in tropomyosin specify shared and isoform-specific regulation of myosins II and V.

N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament.

Investigation into the mechanism of thin filament regulation by transient kinetics and equilibrium binding: Is there a conflict?

A cryo-EM grid preparation device for time-resolved structural studies.

Sample deposition onto cryo-EM grids: from sprays to jets and back.

Need for Speed: Examining Protein Behavior during CryoEM Grid Preparation at Different Timescales.

High-Resolution Cryo-EM Structure of the Cardiac Actomyosin Complex.

The structure of the native cardiac thin filament at systolic Ca levels.

Interaction of the C2 Ig-like Domain of Cardiac Myosin Binding Protein-C with F-actin.

On-grid and in-flow mixing for time-resolved cryo-EM.