Louis Schofield

Genes for glycosylphosphatidylinositol toxin biosynthesis in Plasmodium falciparum.

Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria.

Regulation of murine cerebral malaria pathogenesis by CD1d-restricted NKT cells and the natural killer complex.

The lack of suppressor of cytokine signalling-1 (SOCS1) protects mice from the development of cerebral malaria caused by Plasmodium berghei ANKA.

CD1d-restricted NKT cells contribute to malarial splenomegaly and enhance parasite-specific antibody responses.

MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and Toll-like receptor 2 signaling.

Regulation of immunity and pathogenesis in infectious diseases by CD1d-restricted NKT cells.

Transcriptional profiling reveals suppressed erythropoiesis, up-regulated glycolysis, and interferon-associated responses in murine malaria.

The natural killer complex regulates severe malarial pathogenesis and influences acquired immune responses to Plasmodium berghei ANKA.

Influence of glycosylphosphatidylinositol anchorage on the efficacy of DNA vaccines encoding Plasmodium yoelii merozoite surface protein 4/5.

Immunological processes in malaria pathogenesis.

Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum.

Severe malarial anemia of low parasite burden in rodent models results from accelerated clearance of uninfected erythrocytes.

Clinical immunity to malaria.

Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of the human malaria parasite Plasmodium falciparum.

Preferential invasion of reticulocytes during late-stage Plasmodium berghei infection accounts for reduced circulating reticulocyte levels.

Fatty acids from Plasmodium falciparum down-regulate the toxic activity of malaria glycosylphosphatidylinositols.

CD4+ CD25+ regulatory T cells suppress CD4+ T-cell function and inhibit the development of Plasmodium berghei-specific TH1 responses involved in cerebral malaria pathogenesis.

Intravascular infiltrates and organ-specific inflammation in malaria pathogenesis.

Rational approaches to developing an anti-disease vaccine against malaria.

NK cells stimulate recruitment of CXCR3+ T cells to the brain during Plasmodium berghei-mediated cerebral malaria.

Murine cerebral malaria development is independent of toll-like receptor signaling.

Inhibition of dendritic cell maturation by malaria is dose dependent and does not require Plasmodium falciparum erythrocyte membrane protein 1.

The risk of malarial infections and disease in Papua New Guinean children.

gammadelta-T cells expressing NK receptors predominate over NK cells and conventional T cells in the innate IFN-gamma response to Plasmodium falciparum malaria.

Host-pathogen interactions: pas de deux.

The role of leukocytes bearing Natural Killer Complex receptors and Killer Immunoglobulin-like Receptors in the immunology of malaria.

Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells.

Plasmodium falciparum erythrocyte membrane protein-1 specifically suppresses early production of host interferon-gamma.

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8alpha+ dendritic cells.

Association of early interferon-gamma production with immunity to clinical malaria: a longitudinal study among Papua New Guinean children.

IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection.

Mechanisms underlying early interferon-gamma production in human Plasmodium falciparum malaria.

Cellular tumor necrosis factor, gamma interferon, and interleukin-6 responses as correlates of immunity and risk of clinical Plasmodium falciparum malaria in children from Papua New Guinea.

Analysis of FOXP3+ regulatory T cells that display apparent viral antigen specificity during chronic hepatitis C virus infection.

Estimating the proportion of microarray probes expressed in an RNA sample.

Differential patterns of infection and disease with P. falciparum and P. vivax in young Papua New Guinean children.

Murine cerebral malaria: the whole story.

Natural regulatory T cells in malaria: host or parasite allies?

The role of age and exposure to Plasmodium falciparum in the rate of acquisition of naturally acquired immunity: a randomized controlled trial.

Intermittent preventive treatment for malaria in Papua New Guinean infants exposed to Plasmodium falciparum and P. vivax: a randomized controlled trial.

Effective adjunctive therapy by an innate defense regulatory peptide in a preclinical model of severe malaria.

NK cells and conventional dendritic cells engage in reciprocal activation for the induction of inflammatory responses during Plasmodium berghei ANKA infection.

Efficient Measurement of Opsonising Antibodies to Plasmodium falciparum Merozoites.

Opsonising antibodies to P. falciparum merozoites associated with immunity to clinical malaria.

Molecular evidence for the localization of Plasmodium falciparum immature gametocytes in bone marrow.

Severity of anaemia is associated with bone marrow haemozoin in children exposed to Plasmodium falciparum.

γδ T cells and CD14+ Monocytes Are Predominant Cellular Sources of Cytokines and Chemokines Associated With Severe Malaria.

The contribution of natural killer complex loci to the development of experimental cerebral malaria.

Evaluation of a novel magneto-optical method for the detection of malaria parasites.