Mark A. Baker

Reactive oxygen species generation by human spermatozoa: a continuing enigma.

Development of the signalling pathways associated with sperm capacitation during epididymal maturation.

Biochemical entities involved in reactive oxygen species generation by human spermatozoa.

Oxidative stress in the male germ line and its role in the aetiology of male infertility and genetic disease.

VDAC1 is a transplasma membrane NADH-ferricyanide reductase.

Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation.

Identification of cytochrome P450-reductase as the enzyme responsible for NADPH-dependent lucigenin and tetrazolium salt reduction in rat epididymal sperm preparations.

Redox activity associated with the maturation and capacitation of mammalian spermatozoa.

The importance of redox regulated pathways in sperm cell biology.

Shedding light on chemiluminescence: the application of chemiluminescence in diagnostic andrology.

Oxidative stress and male reproductive biology.

Characterization of VDAC1 as a plasma membrane NADH-oxidoreductase.

Identification of post-translational modifications that occur during sperm maturation using difference in two-dimensional gel electrophoresis.

Identification of cytochrome-b5 reductase as the enzyme responsible for NADH-dependent lucigenin chemiluminescence in human spermatozoa.

Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility.

Oxidative stress, sperm survival and fertility control.

Ontogeny of tyrosine phosphorylation-signaling pathways during spermatogenesis and epididymal maturation in the mouse.

Identification of SRC as a key PKA-stimulated tyrosine kinase involved in the capacitation-associated hyperactivation of murine spermatozoa.

Proteomic changes in mammalian spermatozoa during epididymal maturation.

The role of proteomics in understanding sperm cell biology.

Investigation of the role of SRC in capacitation-associated tyrosine phosphorylation of human spermatozoa.

The mouse sperm proteome characterized via IPG strip prefractionation and LC-MS/MS identification.

As the world grows: contraception in the 21st century.

The rat sperm proteome characterized via IPG strip prefractionation and LC-MS/MS identification.

Bridging the gap between male and female fertility control; contraception-on-demand.

Evaluation and treatment of acute and chronic injuries to the capsular ligaments of the knee.

Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa; its implications during capacitation.

Proteomic insights into spermatozoa: critiques, comments and concerns.

Analysis of proteomic changes associated with sperm capacitation through the combined use of IPG-strip pre-fractionation followed by RP chromatography LC-MS/MS analysis.

Label-free quantitation of phosphopeptide changes during rat sperm capacitation.

New insights into sperm physiology and pathology.

The 'omics revolution and our understanding of sperm cell biology.

Identification of gene products present in Triton X-100 soluble and insoluble fractions of human spermatozoa lysates using LC-MS/MS analysis.

Use of titanium dioxide to find phosphopeptide and total protein changes during epididymal sperm maturation.

The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction.

Proteomic insights into the maturation and capacitation of mammalian spermatozoa.

Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase.

Analysis of phosphopeptide changes as spermatozoa acquire functional competence in the epididymis demonstrates changes in the post-translational modification of Izumo1.

Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumoniae strains with under-acylated lipid A.

Reverse engineering the antigenic architecture of the haemagglutinin from influenza H5N1 clade 1 and 2.2 viruses with fine epitope mapping using monoclonal antibodies.

Towards delineation of a developmental α-importome in the mammalian male germline.

Head and flagella subcompartmental proteomic analysis of human spermatozoa.

Drug-binding energetics of human α-1-acid glycoprotein assessed by isothermal titration calorimetry and molecular docking simulations.

The molecular chaperone HSPA2 plays a key role in regulating the expression of sperm surface receptors that mediate sperm-egg recognition.

Molecular Characterization of Lipopolysaccharide Binding to Human α-1-Acid Glycoprotein.

Causes and consequences of apoptosis in spermatozoa; contributions to infertility and impacts on development.

Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae.

The antigenic architecture of the hemagglutinin of influenza H5N1 viruses.

Phosphoproteomic analysis of peptides.

Oxidative stress, spermatozoa and leukocytic infiltration: relationships forged by the opposing forces of microbial invasion and the search for perfection.

Oxidative stress and male reproductive health.

The α-importome of mammalian germ cell maturation provides novel insights for importin biology.

Proteomic Characterization of Pig Sperm Anterior Head Plasma Membrane Reveals Roles of Acrosomal Proteins in ZP3 Binding.

Analysis of Protein Thiol Changes Occurring During Rat Sperm Epididymal Maturation.