Maytham Hussein

Department of Biochemistry & Pharmacology,
School of Biomedical Sciences,
Faculty of Medicine,
Dentistry and Health Sciences,
Department of Biochemistry & Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences

The University of Melbourne

BIOGRAPHY

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PUBLICATIONS

Lipidomic Analysis of the Outer Membrane Vesicles from Paired Polymyxin-Susceptible and -Resistant Clinical Isolates.

International journal of molecular sciences Aug, 2018 | Pubmed ID: 30103446

A Comparative Study of Outer Membrane Proteome between Paired Colistin-Susceptible and Extremely Colistin-Resistant Klebsiella pneumoniae Strains.

ACS infectious diseases 12, 2018 | Pubmed ID: 30232886

Mechanistic Insights From Global Metabolomics Studies into Synergistic Bactericidal Effect of a Polymyxin B Combination With Tamoxifen Against Cystic Fibrosis MDR .

Computational and structural biotechnology journal , 2018 | Pubmed ID: 30546859

The impact of backbone N-methylation on the structure-activity relationship of Leu -teixobactin.

Journal of peptide science : an official publication of the European Peptide Society Sep, 2019 | Pubmed ID: 31389086

Metabolomics Study of the Synergistic Killing of Polymyxin B in Combination with Amikacin against Polymyxin-Susceptible and -Resistant Pseudomonas aeruginosa.

Antimicrobial agents and chemotherapy 12, 2019 | Pubmed ID: 31611351

Synthesis and structure-activity relationships of teixobactin.

Annals of the New York Academy of Sciences 01, 2020 | Pubmed ID: 31792983

Effective Strategy Targeting Polymyxin-Resistant Gram-Negative Pathogens: Polymyxin B in Combination with the Selective Serotonin Reuptake Inhibitor Sertraline.

ACS infectious diseases 06, 2020 | Pubmed ID: 32427476

The Killing Mechanism of Teixobactin against Methicillin-Resistant Staphylococcus aureus: an Untargeted Metabolomics Study.

mSystems May, 2020 | Pubmed ID: 32457238

The Antimicrobial Activity of Cannabinoids.

Antibiotics (Basel, Switzerland) Jul, 2020 | Pubmed ID: 32668669

Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination.

JCI insight 09, 2020 | Pubmed ID: 32853178

Polymyxin B combinations with FDA-approved non-antibiotic phenothiazine drugs targeting multi-drug resistance of Gram-negative pathogens.

Computational and structural biotechnology journal , 2020 | Pubmed ID: 32952938

Unique mechanistic insights into pathways associated with the synergistic activity of polymyxin B and caspofungin against multidrug-resistant .

Computational and structural biotechnology journal , 2022 | Pubmed ID: 35284046

Mechanisms Underlying Synergistic Killing of Polymyxin B in Combination with Cannabidiol against : A Metabolomic Study.

Pharmaceutics Apr, 2022 | Pubmed ID: 35456620

INSTITUTIONS

The University of Melbourne

JOVE ARTICLES

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

Rajnikant Sharma¹,

Shekhar Yeshwante¹,

Quentin Vallé¹,

Maytham Hussein²,

Varsha Thombare²,

Sean Michael McCann¹,

Robert Maile^3,4,5,

Jian Li⁶,

Tony Velkov²,

Gauri Rao¹

¹UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill,

²Department of Biochemistry & Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne,

³Department of Microbiology & Immunology, University of North Carolina School of Medicine,

⁴Department of Surgery, University of North Carolina at Chapel Hill,

⁵Curriculum in Toxicology and Environmental Medicine, University of North Carolina at Chapel Hill,

⁶Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University

Immunology and Infection

Intraventricular Drug Delivery and Sampling for Pharmacokinetics and Pharmacodynamics Study

Sara Oberrauch¹,

Jing Lu¹,

Linda Cornthwaite-Duncan¹,

Maytham Hussein¹,

Jian Li²,

Gauri Rao³,

Tony Velkov¹

¹Department of Biochemistry & Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne,

²Department of Microbiology, Biomedicine Discovery Institute, Monash University,

³UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill

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