Otmar Schober

Cardiac autonomic dysfunction in Brugada syndrome.

Prognostic significance of amino acid transport imaging in patients with brain tumors.

3-[123I]Iodo-L-alpha-methyl tyrosine transport into human fibroblasts and comparison with Ewing's sarcoma cells.

Prognostic significance of (18)F-FDG and (99m)Tc-methylene diphosphonate uptake in primary osteosarcoma.

[Highlights of the 40th anniversary of the German Society of Nuclear Medicine in Frreiburg].

Noninvasive grading of untreated gliomas: a comparative study of MR imaging and 3-(iodine 123)-L-alpha-methyltyrosine SPECT.

Direct epicardial mapping can differentiate hibernating from scarred myocardium: a validation study with 18F-FDG-PET.

Biochemical mechanisms of hibernation and stunning in the human heart.

Design of new beta1-selective adrenoceptor ligands as potential radioligands for in vivo imaging.

Acute toxicity of adjuvant radiotherapy in locally advanced differentiated thyroid carcinoma. First results of the multicenter study differentiated thyroid carcinoma (MSDS).

Direct epicardial mapping predicts the recovery of left ventricular dysfunction in chronic ischaemic myocardium.

Synthesis and preliminary biological evaluation of new radioiodinated MMP inhibitors for imaging MMP activity in vivo.

Scintigraphic imaging of matrix metalloproteinase activity in the arterial wall in vivo.

[Subclinical thyroid disease].

Early effects of irradiation on [(123)I]-IMT and [(18)F]-FDG uptake in rat C6 glioma cells.

Synthesis and first in vivo evaluation of new selective high affinity beta1-adrenoceptor radioligands for SPECT based on ICI 89,406.

Functional changes after partial left ventriculectomy and mitral valve repair assessed by gated perfusion SPECT.

Abnormal myocardial presynaptic norepinephrine recycling in patients with Brugada syndrome.

High-density lipoprotein stimulates myocardial perfusion in vivo.

Proliferation-dependent changes in amino acid transport and glucose metabolism in glioma cell lines.

Is whole-body FDG-PET valuable for health screening? Against.

ECG-triggered high-resolution positron emission tomography: a breakthrough in cardiac molecular imaging of mice.

C-5-disubstituted barbiturates as potential molecular probes for noninvasive matrix metalloproteinase imaging.

Performance evaluation of the 32-module quadHIDAC small-animal PET scanner.

Monitoring left ventricular dilation in mice with PET.

[Scintigraphic molecular imaging].

The prognostic value of [F]FDG-PET in nonrefractory partial epilepsy.

Synthesis, in vitro pharmacology and biodistribution studies of new PD 156707-derived ET(A) receptor radioligands.

1 + 1 = 3.

Impact of sympathetic innervation on recurrent life-threatening arrhythmias in the follow-up of patients with idiopathic ventricular fibrillation.

Gated listmode acquisition with the quadHIDAC animal PET to image mouse hearts.

Organ movement reduction in PET/CT using dual-gated list-mode acquisition.

Is PET/CT necessary in paediatric oncology? For.

Idiopathic left ventricular aneurysm and sudden cardiac death in young adults.

Successful high-resolution animal positron emission tomography of human Ewing tumours and their metastases in a murine xenograft model.

High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor.

Whole-body PET/CT with 11C-meta-hydroxyephedrine in tumors of the sympathetic nervous system: feasibility study and comparison with 123I-MIBG SPECT/CT.

[Ethics and pediatrics in nuclear medicine].

Accurate noninvasive measurement of infarct size in mice with high-resolution PET.

5-pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis.

Molecular cardiovascular imaging using scintigraphic methods.

Quantification of left ventricular volumes and ejection fraction from gated 99mTc-MIBI SPECT: validation of an elastic surface model approach in comparison to cardiac magnetic resonance imaging, 4D-MSPECT and QGS.

A fluorescent photoprobe for the imaging of endothelin receptors.

[Nuclear medicine and radiation].

Effective methods to correct contrast agent-induced errors in PET quantification in cardiac PET/CT.

Impaired myocardial perfusion and perfusion reserve associated with increased coronary resistance in persistent idiopathic atrial fibrillation.

Respiratory gating in positron emission tomography: a quantitative comparison of different gating schemes.

Are [O-methyl-11C]derivatives of ICI 89,406 beta1-adrenoceptor selective radioligands suitable for PET?

Novel fluorinated derivatives of the broad-spectrum MMP inhibitors N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](benzyl)- and (3-picolyl)-amino]-3-methyl-butanamide as potential tools for the molecular imaging of activated MMPs with PET.

Significant benefit of multimodal imaging: PET/CT compared with PET alone in staging and follow-up of patients with Ewing tumors.

Clinical molecular imaging in intestinal graft-versus-host disease: mapping of disease activity, prediction, and monitoring of treatment efficiency by positron emission tomography.

EANM-ESR white paper on multimodality imaging.

(18)F-labelled cardiac PET tracers: selected probes for the molecular imaging of transporters, receptors and proteases.

Diagnostic impact of 18F-FDG PET-CT evaluating solid pancreatic lesions versus endosonography, endoscopic retrograde cholangio-pancreatography with intraductal ultrasonography and abdominal ultrasound.

Dynamic 18F-fluoride small animal PET to noninvasively assess renal function in rats.

A new 18F-labelled derivative of the MMP inhibitor CGS 27023A for PET: radiosynthesis and initial small-animal PET studies.

Myocardial perfusion in nonischemic dilated cardiomyopathy with and without atrial fibrillation.

Fluorinated isatin derivatives. Part 1: synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins as potent caspase-3 and -7 inhibitors.

Clinical outcomes of adjuvant external-beam radiotherapy for differentiated thyroid cancer - results after 874 patient-years of follow-up in the MSDS-trial.

[Should all patients with thyroid nodules > or = 1 cm undergo fine-needle aspiration biopsy?].

[Position paper nuclear cardiology: update 2008].

Biodistribution of a nonpeptidic fluorescent endothelin A receptor imaging probe.

Impact of (18)F-FDG-PET/CT on staging and irradiation of patients with locally advanced rectal cancer.

List mode-driven cardiac and respiratory gating in PET.

Synthesis and evaluation of a novel hydroxamate based fluorescent photoprobe for imaging of matrix metalloproteinases.

Non-invasive imaging of acute renal allograft rejection in rats using small animal F-FDG-PET.

Evaluation and comparison of 11C-choline uptake and calcification in aortic and common carotid arterial walls with combined PET/CT.

Fluorinated isatin derivatives. Part 2. New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis.

Small-animal PET: a promising, non-invasive tool in pre-clinical research.

Optimal number of respiratory gates in positron emission tomography: a cardiac patient study.

Molecular imaging of apoptosis in vivo with scintigraphic and optical biomarkers--a status report.

PET-compatible endothelin receptor radioligands: synthesis and first in vitro and in vivo studies.

Acute renal failure due to primary bilateral renal large B-cell lymphoma: diagnostics and follow-up by FDG-PET/CT.

Radiofluorinated pyrimidine-2,4,6-triones as molecular probes for noninvasive MMP-targeted imaging.

Matrix-metalloproteinases as imaging targets for inflammatory activity in atherosclerotic plaques.

Preclinical evaluation of an 18F-labelled beta1-adrenoceptor selective radioligand based on ICI 89,406.

Detection of respiratory tumour motion using intrinsic list mode-driven gating in positron emission tomography.

Primary tumour size is a prognostic parameter in patients suffering from differentiated thyroid carcinoma with extrathyroidal growth: results of the MSDS trial.

Molecular imaging of cardiac sympathetic innervation by 11C-mHED and PET: from man to mouse?

Synthesis of geminal difluorides by oxidative desulfurization-difluorination of alkyl aryl thioethers with halonium electrophiles in the presence of fluorinating reagents and its application for 18F-radiolabeling.

Three-dimensional echocardiography and 153Sm-EDTMP SPECT/CT in extensive cardiac metastases from osteosarcoma.

Potential of noninvasive serial assessment of acute renal allograft rejection by 18F-FDG PET to monitor treatment efficiency.

Development and evaluation of endothelin-A receptor (radio)ligands for positron emission tomography.

Subvalvular hypertrophic calcification of the mitral annulus: [(18)F]FDG-PET-CT, MRI, and echocardiography findings.

The MMP inhibitor (R)-2-(N-benzyl-4-(2-[18F]fluoroethoxy)phenylsulphonamido)-N-hydroxy-3-methylbutanamide: Improved precursor synthesis and fully automated radiosynthesis.

Fluorinated isatin derivatives. Part 3. New side-chain fluoro-functionalized pyrrolidinyl sulfonyl isatins as potent caspase-3 and -7 inhibitors.

The diagnosis and treatment of acute pulmonary embolism. Don't forget scintigraphy in pulmonary embolism.

PET in the diagnosis and management of patients with brain metastasis: current role and future perspectives.

Impaired cardiac sympathetic innervation in symptomatic patients with long QT syndrome.

[18F]Fluorodeoxyglucose positron emission tomography for detection of bone marrow involvement in children and adolescents with Hodgkin's lymphoma.

Contribution of PET/CT to prediction of outcome in children and young adults with rhabdomyosarcoma.

Cardiac sympathetic dysfunction in genotyped patients with arrhythmogenic right ventricular cardiomyopathy and risk of recurrent ventricular tachyarrhythmias.

Hydroxyfasudil-mediated inhibition of ROCK1 and ROCK2 improves kidney function in rat renal acute ischemia-reperfusion injury.

Microvascular dysfunction in nonfailing arrhythmogenic right ventricular cardiomyopathy.

A new generation of radiofluorinated pyrimidine-2,4,6-triones as MMP-targeted radiotracers for positron emission tomography.

Detection and differentiation of inflammatory versus fibromatous Crohn's disease strictures: prospective comparison of 18F-FDG-PET/CT, MR-enteroclysis, and transabdominal ultrasound versus endoscopic/histologic evaluation.

Left ventricular dilation and functional impairment assessed by gated SPECT are indicators of cardiac allograft vasculopathy in heart transplant recipients.

Non-FDG imaging of atherosclerosis: will imaging of MMPs assess plaque vulnerability?

Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial.

Assessment of endothelin-A receptor expression in subcutaneous and orthotopic thyroid carcinoma xenografts in vivo employing optical imaging methods.

A new class of highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamates: (radio)synthesis and in vitro and first in vivo evaluation.

Ectopic thyroid mass in the heart.

Differentiation of malignant and benign cardiac tumors using 18F-FDG PET/CT.

Systematic evaluation of 99mTc-tetrofosmin versus 99mTc-sestamibi to study murine myocardial perfusion in small animal SPECT/CT.

Radiosynthesis of a ⁶⁸Ga labeled matrix metalloproteinase inhibitor as a potential probe for PET imaging.

Reply.

Efficient synthesis of a fluorine-18 labeled biotin derivative.

Intraoperative 3-D mapping of parathyroid adenoma using freehand SPECT.

External radioactive markers for PET data-driven respiratory gating in positron emission tomography.

Synthesis of new fluorinated, 2-substituted 5-pyrrolidinylsulfonyl isatin derivatives as caspase-3 and caspase-7 inhibitors: nonradioactive counterparts of putative PET-compatible apoptosis imaging agents.

Myocardial perfusion imaging and coronary calcium scoring with a two-slice SPECT/CT system: can the attenuation map be calculated from the calcium scoring CT scan?

German Association of Endocrine Surgeons practice guideline for the surgical management of malignant thyroid tumors.