ARC-Net Research Centre,
Department of Diagnostics and Public Health,
Section of Pathology,
Department of Diagnostics and Public Health, Section of Pathology
Vincenzo Corbo is an Assistant Professor at the University of Verona, Verona, Italy. He received his undergraduate with honors degree from University of Naples, and a Ph.D. from the University of Verona, Italy.
During his training he developed a keen focus on cancer genetics, especially of pancreatic malignancies. As a post-doctoral fellow in David Tuveson's lab at the Cold Spring Harbor Laboratory (NY, USA), he co-developed the organoid culture system of pancreatic ductal cells and used that system to identify malignant-specific responses to pharmacological perturbation.
Dr. Corbo received a Start-up Grant from AIRC (Associazione Italiana Ricerca sul Cancro) in 2016 and started his own lab at the University of Verona. His research program encompasses using different experimental models and clinical tissues to understand how intra-tumor heterogeneity and cell plasticity drive the progression of pancreatic cancers.
Time-Qualified Patterns of Variation of PPARγ, DNMT1, and DNMT3B Expression in Pancreatic Cancer Cell Lines.
PPAR research , 2012 | Pubmed ID: 22966223
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.
Nature Nov, 2012 | Pubmed ID: 23103869
MEN1 gene mutation and reduced expression are associated with poor prognosis in pulmonary carcinoids.
The Journal of clinical endocrinology and metabolism Feb, 2014 | Pubmed ID: 24276465
Clinical application of microRNA testing in neuroendocrine tumors of the gastrointestinal tract.
Molecules (Basel, Switzerland) , 2014 | Pubmed ID: 24566314
Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups.
Oncotarget May, 2014 | Pubmed ID: 24867389
Reporting tumor molecular heterogeneity in histopathological diagnosis.
PloS one , 2014 | Pubmed ID: 25127237
Whole genomes redefine the mutational landscape of pancreatic cancer.
Nature Feb, 2015 | Pubmed ID: 25719666
Feasibility and safety of electrochemotherapy (ECT) in the pancreas: a pre-clinical investigation.
Radiology and oncology Jun, 2015 | Pubmed ID: 26029026
Genomic analyses identify molecular subtypes of pancreatic cancer.
Nature Mar, 2016 | Pubmed ID: 26909576
Hypermutation In Pancreatic Cancer.
Gastroenterology 01, 2017 | Pubmed ID: 27856273
Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin-remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D.
The Journal of pathology 03, 2017 | Pubmed ID: 27873319
Whole-genome landscape of pancreatic neuroendocrine tumours.
Nature 03, 2017 | Pubmed ID: 28199314
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.
The Journal of experimental medicine 03, 2017 | Pubmed ID: 28232471
Fhit down-regulation is an early event in pancreatic carcinogenesis.
Virchows Archiv : an international journal of pathology Jun, 2017 | Pubmed ID: 28289900
Lack of Association for Reported Endocrine Pancreatic Cancer Risk Loci in the PANDoRA Consortium.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 08, 2017 | Pubmed ID: 28765340
Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma.
Scientific reports 05, 2018 | Pubmed ID: 29740198
PD-1, PD-L1, and CD163 in pancreatic undifferentiated carcinoma with osteoclast-like giant cells: expression patterns and clinical implications.
Human pathology 11, 2018 | Pubmed ID: 30031096
ERG alterations and mTOR pathway activation in primary prostate carcinomas developing castration-resistance.
Pathology, research and practice Oct, 2018 | Pubmed ID: 30190183
Mutational and copy number asset of primary sporadic neuroendocrine tumors of the small intestine.
Virchows Archiv : an international journal of pathology Dec, 2018 | Pubmed ID: 30219970
Molecular alterations associated with metastases of solid pseudopapillary neoplasms of the pancreas.
The Journal of pathology Jan, 2019 | Pubmed ID: 30306561
Perineural Invasion is a Strong Prognostic Moderator in Ampulla of Vater Carcinoma: A Meta-analysis.
Pancreas 01, 2019 | Pubmed ID: 30451797
Gene Expression Profiling of Lung Atypical Carcinoids and Large Cell Neuroendocrine Carcinomas Identifies Three Transcriptomic Subtypes with Specific Genomic Alterations.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer Sep, 2019 | Pubmed ID: 31085341
Preclinical Modelling of PDA: Is Organoid the New Black?
International journal of molecular sciences Jun, 2019 | Pubmed ID: 31195689
Muscle derangement and alteration of the nutritional machinery in NSCLC.
Critical reviews in oncology/hematology Sep, 2019 | Pubmed ID: 31228648
PTEN in Lung Cancer: Dealing with the Problem, Building on New Knowledge and Turning the Game Around.
Cancers Aug, 2019 | Pubmed ID: 31404976
Immunoevolution of mouse pancreatic organoid isografts from preinvasive to metastatic disease.
Scientific reports Aug, 2019 | Pubmed ID: 31439856
Immunosuppression by monocytic myeloid-derived suppressor cells in patients with pancreatic ductal carcinoma is orchestrated by STAT3.
Journal for immunotherapy of cancer Sep, 2019 | Pubmed ID: 31533831
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