Nica Borgese

Trafficking of tail-anchored proteins: transport from the endoplasmic reticulum to the plasma membrane and sorting between surface domains in polarised epithelial cells.

Translocation of the C terminus of a tail-anchored protein across the endoplasmic reticulum membrane in yeast mutants defective in signal peptide-driven translocation.

KDEL and KKXX retrieval signals appended to the same reporter protein determine different trafficking between endoplasmic reticulum, intermediate compartment, and Golgi complex.

Activation of endothelial nitric-oxide synthase by tumor necrosis factor-alpha: a novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3' kinase, and Akt.

The tale of tail-anchored proteins: coming from the cytosol and looking for a membrane.

Interactions between nitric oxide and sphingolipids and the potential consequences in physiology and pathology.

Formation of stacked ER cisternae by low affinity protein interactions.

N-myristoylation determines dual targeting of mammalian NADH-cytochrome b5 reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning.

A cellular system to study the role of nitric oxide in cell death, survival, and migration.

Transmembrane topogenesis of a tail-anchored protein is modulated by membrane lipid composition.

Two tail-anchored protein variants, differing in transmembrane domain length and intracellular sorting, interact differently with lipids.

Endothelial nitric oxide synthase is segregated from caveolin-1 and localizes to the leading edge of migrating cells.

Endoplasmic reticulum architecture: structures in flux.

Dynamic and reversible restructuring of the ER induced by PDMP in cultured cells.

Cell culture models to investigate the selective vulnerability of motoneuronal mitochondria to familial ALS-linked G93ASOD1.

Unassisted translocation of large polypeptide domains across phospholipid bilayers.

How tails guide tail-anchored proteins to their destinations.

Transmembrane domain-dependent partitioning of membrane proteins within the endoplasmic reticulum.

The quest for a better resolution of protein-translocation processes. Conference on the Control, Co-ordination and Regulation of Protein Targeting and Translocation.

The role of cytosolic proteins in the insertion of tail-anchored proteins into phospholipid bilayers.

Basal nitric oxide release attenuates cell migration of HeLa and endothelial cells.

A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum.

Remote origins of tail-anchored proteins.

Targeting pathways of C-tail-anchored proteins.

Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein.

Chronic deficiency of nitric oxide affects hypoxia inducible factor-1α (HIF-1α) stability and migration in human endothelial cells.

Restructured endoplasmic reticulum generated by mutant amyotrophic lateral sclerosis-linked VAPB is cleared by the proteasome.

CDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1) is a tail-anchored protein in the endoplasmic reticulum (ER) of insulinoma cells.

Uncovering common principles in protein export of malaria parasites.

PI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins.

Nicotine-modulated subunit stoichiometry affects stability and trafficking of α3β4 nicotinic receptor.