Department of Microbiology,
Department of Medicine
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Effects of influenza A virus NS1 protein on protein expression: the NS1 protein enhances translation and is not required for shutoff of host protein synthesis.
Journal of virology Feb, 2002 | Pubmed ID: 11773396
Apical budding of a recombinant influenza A virus expressing a hemagglutinin protein with a basolateral localization signal.
Journal of virology Apr, 2002 | Pubmed ID: 11884578
New directions in vaccine research.
The Journal of clinical investigation Jun, 2002 | Pubmed ID: 12070295
Influenza vaccines: present and future.
The Journal of clinical investigation Jul, 2002 | Pubmed ID: 12093881
Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2002 | Pubmed ID: 12149435
The makings of a killer.
Nature medicine Sep, 2002 | Pubmed ID: 12205448
Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2002 | Pubmed ID: 12368467
Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains.
Journal of virology Dec, 2002 | Pubmed ID: 12438621
Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins.
Journal of virology Jan, 2003 | Pubmed ID: 12502864
Activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs) by human dendritic cells infected with an attenuated influenza A virus expressing a CTL epitope derived from the HER-2/neu proto-oncogene.
Journal of virology Jul, 2003 | Pubmed ID: 12805440
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
Journal of virology Jul, 2003 | Pubmed ID: 12829834
Chimeric influenza A viruses with a functional influenza B virus neuraminidase or hemagglutinin.
Journal of virology Sep, 2003 | Pubmed ID: 12915528
Newcastle disease virus V protein is a determinant of host range restriction.
Journal of virology Sep, 2003 | Pubmed ID: 12915566
Trafficking of viral genomic RNA into and out of the nucleus: influenza, Thogoto and Borna disease viruses.
Virus research Sep, 2003 | Pubmed ID: 12921991
Induction of protective immunity against malaria by priming-boosting immunization with recombinant cold-adapted influenza and modified vaccinia Ankara viruses expressing a CD8+-T-cell epitope derived from the circumsporozoite protein of Plasmodium yoelii.
Journal of virology Nov, 2003 | Pubmed ID: 14557672
Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2004 | Pubmed ID: 14745017
Structure of the uncleaved human H1 hemagglutinin from the extinct 1918 influenza virus.
Science (New York, N.Y.) Mar, 2004 | Pubmed ID: 14764887
Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2004 | Pubmed ID: 14963236
Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively.
Journal of virology Jun, 2004 | Pubmed ID: 15140960
Induction of cellular immune responses to simian immunodeficiency virus gag by two recombinant negative-strand RNA virus vectors.
Journal of virology Sep, 2004 | Pubmed ID: 15308731
Influenza: old and new threats.
Nature medicine Dec, 2004 | Pubmed ID: 15577936
An unconventional NLS is critical for the nuclear import of the influenza A virus nucleoprotein and ribonucleoprotein.
Traffic (Copenhagen, Denmark) Mar, 2005 | Pubmed ID: 15702989
A novel paramyxovirus?
Emerging infectious diseases Jan, 2005 | Pubmed ID: 15705331
Nuclear localization of the Nipah virus W protein allows for inhibition of both virus- and toll-like receptor 3-triggered signaling pathways.
Journal of virology May, 2005 | Pubmed ID: 15857993
Stimulation of human T cells by an influenza A vector expressing a CTL epitope from the HER-2/neu protooncogene results in higher numbers of antigen-specific TCRhi cells than stimulation with peptide. Divergent roles of IL-2 and IL-15.
Anticancer research Mar-Apr, 2005 | Pubmed ID: 15868901
Attenuation of equine influenza viruses through truncations of the NS1 protein.
Journal of virology Jul, 2005 | Pubmed ID: 15956587
A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity.
Journal of virology Sep, 2005 | Pubmed ID: 16103207
Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1.
PLoS pathogens Sep, 2005 | Pubmed ID: 16201016
Characterization of the reconstructed 1918 Spanish influenza pandemic virus.
Science (New York, N.Y.) Oct, 2005 | Pubmed ID: 16210530
Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice.
Journal of virology Dec, 2005 | Pubmed ID: 16282492
Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities.
Journal of molecular biology Feb, 2006 | Pubmed ID: 16343533
7a protein of severe acute respiratory syndrome coronavirus inhibits cellular protein synthesis and activates p38 mitogen-activated protein kinase.
Journal of virology Jan, 2006 | Pubmed ID: 16378980
What can we learn from reconstructing the extinct 1918 pandemic influenza virus?
Immunity Feb, 2006 | Pubmed ID: 16473822
Making better influenza virus vaccines?
Emerging infectious diseases Jan, 2006 | Pubmed ID: 16494719
Sequence analysis and receptor specificity of the hemagglutinin of a recent influenza H2N2 virus isolated from chicken in North America.
Glycoconjugate journal Feb, 2006 | Pubmed ID: 16575526
Engineered viral vaccine constructs with dual specificity: avian influenza and Newcastle disease.
Proceedings of the National Academy of Sciences of the United States of America May, 2006 | Pubmed ID: 16717196
The guinea pig as a transmission model for human influenza viruses.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2006 | Pubmed ID: 16785447
Influenza A virus PB1-F2 protein contributes to viral pathogenesis in mice.
Journal of virology Aug, 2006 | Pubmed ID: 16873254
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus.
Nature Oct, 2006 | Pubmed ID: 17006449
Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists.
Journal of virology Jan, 2007 | Pubmed ID: 17108024
A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission.
Science (New York, N.Y.) Feb, 2007 | Pubmed ID: 17272724
Effective replication of human influenza viruses in mice lacking a major alpha2,6 sialyltransferase.
Virus research Jun, 2007 | Pubmed ID: 17313986
Live-attenuated influenza viruses as delivery vectors for Chlamydia vaccines.
Immunology Sep, 2007 | Pubmed ID: 17451464
Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane.
Journal of virology Sep, 2007 | Pubmed ID: 17596301
Specific residues of the influenza A virus hemagglutinin viral RNA are important for efficient packaging into budding virions.
Journal of virology Sep, 2007 | Pubmed ID: 17634232
A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence.
PLoS pathogens Oct, 2007 | Pubmed ID: 17922571
Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic.
Nature immunology Nov, 2007 | Pubmed ID: 17952044
Influenza virus transmission is dependent on relative humidity and temperature.
PLoS pathogens Oct, 2007 | Pubmed ID: 17953482
Influenza A virus PB1-F2: a small protein with a big punch.
Cell host & microbe Oct, 2007 | Pubmed ID: 18005736
A combination in-ovo vaccine for avian influenza virus and Newcastle disease virus.
Vaccine Jan, 2008 | Pubmed ID: 18093698
Highly conserved regions of influenza a virus polymerase gene segments are critical for efficient viral RNA packaging.
Journal of virology Mar, 2008 | Pubmed ID: 18094182
Human genes and influenza.
The Journal of infectious diseases Jan, 2008 | Pubmed ID: 18171276
Expression of transgenes from newcastle disease virus with a segmented genome.
Journal of virology Mar, 2008 | Pubmed ID: 18199643
Influenza virus transmission: basic science and implications for the use of antiviral drugs during a pandemic.
Infectious disorders drug targets Dec, 2007 | Pubmed ID: 18220963
Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2008 | Pubmed ID: 18287069
High temperature (30 degrees C) blocks aerosol but not contact transmission of influenza virus.
Journal of virology Jun, 2008 | Pubmed ID: 18367530
Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2008 | Pubmed ID: 18413603
A seven-segmented influenza A virus expressing the influenza C virus glycoprotein HEF.
Journal of virology Jul, 2008 | Pubmed ID: 18448539
Cellular proteins in influenza virus particles.
PLoS pathogens Jun, 2008 | Pubmed ID: 18535660
Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity.
Antiviral research Nov, 2008 | Pubmed ID: 18585796
Oseltamivir-resistant influenza A viruses are transmitted efficiently among guinea pigs by direct contact but not by aerosol.
Journal of virology Oct, 2008 | Pubmed ID: 18684820
Influenza B virus NS1-truncated mutants: live-attenuated vaccine approach.
Journal of virology Nov, 2008 | Pubmed ID: 18768976
Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza.
Journal of virology Feb, 2009 | Pubmed ID: 19073731
Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N.
PLoS pathogens Jan, 2009 | Pubmed ID: 19119420
Unsung hero Robert C. Gallo.
Science (New York, N.Y.) Jan, 2009 | Pubmed ID: 19131607
Blocking interhost transmission of influenza virus by vaccination in the guinea pig model.
Journal of virology Apr, 2009 | Pubmed ID: 19153237
Enhancement of oncolytic properties of recombinant newcastle disease virus through antagonism of cellular innate immune responses.
Molecular therapy : the journal of the American Society of Gene Therapy Apr, 2009 | Pubmed ID: 19209145
Nipah virus edits its P gene at high frequency to express the V and W proteins.
Journal of virology Apr, 2009 | Pubmed ID: 19211754
The biology of influenza viruses.
Vaccine Sep, 2008 | Pubmed ID: 19230160
Universal epitopes of influenza virus hemagglutinins?
Nature structural & molecular biology Mar, 2009 | Pubmed ID: 19234464
Transmission of influenza virus via aerosols and fomites in the guinea pig model.
The Journal of infectious diseases Mar, 2009 | Pubmed ID: 19434931
Preparation of genetically engineered A/H5N1 and A/H7N1 pandemic vaccine viruses by reverse genetics in a mixture of Vero and chicken embryo cells.
Influenza and other respiratory viruses May, 2007 | Pubmed ID: 19453414
Alpha-C-galactosylceramide as an adjuvant for a live attenuated influenza virus vaccine.
Vaccine Jun, 2009 | Pubmed ID: 19464560
Unraveling the mystery of swine influenza virus.
Cell Jun, 2009 | Pubmed ID: 19524497
Recombinant vectors as influenza vaccines.
Current topics in microbiology and immunology , 2009 | Pubmed ID: 19768410
Rewiring the RNAs of influenza virus to prevent reassortment.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2009 | Pubmed ID: 19805230
Transmission of pandemic H1N1 influenza virus and impact of prior exposure to seasonal strains or interferon treatment.
Journal of virology Jan, 2010 | Pubmed ID: 19828604
Detection of free peritoneal cancer cells in gastric cancer using cancer-specific Newcastle disease virus.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract Jan, 2010 | Pubmed ID: 19902312
Hemagglutinin-pseudotyped green fluorescent protein-expressing influenza viruses for the detection of influenza virus neutralizing antibodies.
Journal of virology Feb, 2010 | Pubmed ID: 19939917
Transmission of influenza virus in temperate zones is predominantly by aerosol, in the tropics by contact: a hypothesis.
PLoS currents , 2009 | Pubmed ID: 20025197
Human host factors required for influenza virus replication.
Nature Feb, 2010 | Pubmed ID: 20027183
Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines.
PLoS pathogens Jan, 2010 | Pubmed ID: 20126449
PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal models.
Journal of virology May, 2010 | Pubmed ID: 20181699
Broadly protective monoclonal antibodies against H3 influenza viruses following sequential immunization with different hemagglutinins.
PLoS pathogens Feb, 2010 | Pubmed ID: 20195520
A nine-segment influenza a virus carrying subtype H1 and H3 hemagglutinins.
Journal of virology Aug, 2010 | Pubmed ID: 20519387
Protection from the 2009 H1N1 pandemic influenza by an antibody from combinatorial survivor-based libraries.
PLoS pathogens , 2010 | Pubmed ID: 20628565
Influenza virus vaccine based on the conserved hemagglutinin stalk domain.
mBio Apr, 2010 | Pubmed ID: 20689752
Oseltamivir-resistant variants of the 2009 pandemic H1N1 influenza A virus are not attenuated in the guinea pig and ferret transmission models.
Journal of virology Nov, 2010 | Pubmed ID: 20739532
Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2010 | Pubmed ID: 20956293
Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus.
Nature communications , 2010 | Pubmed ID: 20975689
A single N66S mutation in the PB1-F2 protein of influenza A virus increases virulence by inhibiting the early interferon response in vivo.
Journal of virology Jan, 2011 | Pubmed ID: 21084483
Transmission of a 2009 pandemic influenza virus shows a sensitivity to temperature and humidity similar to that of an H3N2 seasonal strain.
Journal of virology Feb, 2011 | Pubmed ID: 21084485
Newcastle disease virus expressing a dendritic cell-targeted HIV gag protein induces a potent gag-specific immune response in mice.
Journal of virology Mar, 2011 | Pubmed ID: 21159873
Budding capability of the influenza virus neuraminidase can be modulated by tetherin.
Journal of virology Mar, 2011 | Pubmed ID: 21209114
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2011 | Pubmed ID: 21436031
Oncolytic specificity of Newcastle disease virus is mediated by selectivity for apoptosis-resistant cells.
Journal of virology Jun, 2011 | Pubmed ID: 21471241
A reassortment-incompetent live attenuated influenza virus vaccine for protection against pandemic virus strains.
Journal of virology Jul, 2011 | Pubmed ID: 21543486
The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein.
PLoS pathogens Jun, 2011 | Pubmed ID: 21695240
Biochemistry. Catching a moving target.
Science (New York, N.Y.) Aug, 2011 | Pubmed ID: 21836007
Why do influenza virus subtypes die out? A hypothesis.
mBio , 2011 | Pubmed ID: 21878571
The M segment of the 2009 new pandemic H1N1 influenza virus is critical for its high transmission efficiency in the guinea pig model.
Journal of virology Nov, 2011 | Pubmed ID: 21880744
The DBA.2 mouse is susceptible to disease following infection with a broad, but limited, range of influenza A and B viruses.
Journal of virology Dec, 2011 | Pubmed ID: 21917963
Therapeutic effects of a fusogenic newcastle disease virus in treating head and neck cancer.
Head & neck Oct, 2011 | Pubmed ID: 21928411
The influenza A virus protein PB1-F2: killing two birds with one stone?
Virulence Nov-Dec, 2011 | Pubmed ID: 21971186
Don't censor life-saving science.
Nature Jan, 2012 | Pubmed ID: 22237069
Pause on Avian Flu Transmission Research.
Science (New York, N.Y.) Jan, 2012 | Pubmed ID: 22267586
Pause on avian flu transmission research.
Science (New York, N.Y.) Jan, 2012 | Pubmed ID: 22282787
Transmission of influenza B viruses in the guinea pig.
Journal of virology Apr, 2012 | Pubmed ID: 22301149
H5N1 influenza viruses: facts, not fear.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2012 | Pubmed ID: 22308474
Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2012 | Pubmed ID: 22308500
Efficient transmission of pandemic H1N1 influenza viruses with high-level oseltamivir resistance.
Journal of virology May, 2012 | Pubmed ID: 22345446
Seroevidence for H5N1 influenza infections in humans: meta-analysis.
Science (New York, N.Y.) Mar, 2012 | Pubmed ID: 22362880
Oncolytic Newcastle disease virus for cancer therapy: old challenges and new directions.
Future microbiology Mar, 2012 | Pubmed ID: 22393889
Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes.
Journal of virology May, 2012 | Pubmed ID: 22398287
Attenuated influenza virus construct with enhanced hemagglutinin protein expression.
Journal of virology May, 2012 | Pubmed ID: 22398291
A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo.
Journal of virology Jun, 2012 | Pubmed ID: 22491456
The influenza A virus PB2, PA, NP, and M segments play a pivotal role during genome packaging.
Journal of virology Jul, 2012 | Pubmed ID: 22532680
One influenza virus particle packages eight unique viral RNAs as shown by FISH analysis.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2012 | Pubmed ID: 22547828
A novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferon.
PLoS pathogens , 2012 | Pubmed ID: 22577360
Influenza virus protein PB1-F2 inhibits the induction of type I interferon by binding to MAVS and decreasing mitochondrial membrane potential.
Journal of virology Aug, 2012 | Pubmed ID: 22674996
Influenza virus infection in guinea pigs raised as livestock, Ecuador.
Emerging infectious diseases Jul, 2012 | Pubmed ID: 22710350
NS1-truncated live attenuated virus vaccine provides robust protection to aged mice from viral challenge.
Journal of virology Oct, 2012 | Pubmed ID: 22787224
Hemagglutinin Stalk-Reactive Antibodies Are Boosted following Sequential Infection with Seasonal and Pandemic H1N1 Influenza Virus in Mice.
Journal of virology Oct, 2012 | Pubmed ID: 22787225
A majority of infectious Newcastle disease virus particles contain a single genome, while a minority contain multiple genomes.
Journal of virology Oct, 2012 | Pubmed ID: 22787227
A carboxy-terminal trimerization domain stabilizes conformational epitopes on the stalk domain of soluble recombinant hemagglutinin substrates.
PloS one , 2012 | Pubmed ID: 22928001
Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Nature Sep, 2012 | Pubmed ID: 22982990
1976 and 2009 H1N1 influenza virus vaccines boost anti-hemagglutinin stalk antibodies in humans.
The Journal of infectious diseases Jan, 2013 | Pubmed ID: 23087428
Identification of small molecules with type I interferon inducing properties by high-throughput screening.
PloS one , 2012 | Pubmed ID: 23145065
Toward a universal influenza virus vaccine: prospects and challenges.
Annual review of medicine , 2013 | Pubmed ID: 23327522
Transmission studies resume for avian flu.
Science (New York, N.Y.) Feb, 2013 | Pubmed ID: 23345603
H3N2 influenza virus infection induces broadly reactive hemagglutinin stalk antibodies in humans and mice.
Journal of virology Apr, 2013 | Pubmed ID: 23408625
Serum- and glucocorticoid-regulated kinase 1 is required for nuclear export of the ribonucleoprotein of influenza A virus.
Journal of virology May, 2013 | Pubmed ID: 23487453
Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies.
Journal of virology Jun, 2013 | Pubmed ID: 23576508
Colocalization of Different Influenza Viral RNA Segments in the Cytoplasm before Viral Budding as Shown by Single-molecule Sensitivity FISH Analysis.
PLoS pathogens May, 2013 | Pubmed ID: 23671419
Recombinant IgA is sufficient to prevent influenza virus transmission in guinea pigs.
Journal of virology Jul, 2013 | Pubmed ID: 23698296
Induction of cross-reactive antibodies to novel H7N9 influenza virus by recombinant Newcastle disease virus expressing a North American lineage H7 subtype hemagglutinin.
Journal of virology Jul, 2013 | Pubmed ID: 23698299
In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies.
Journal of virology Aug, 2013 | Pubmed ID: 23698304
A small molecule multi-kinase inhibitor reduces influenza A virus replication by restricting viral RNA synthesis.
Antiviral research Jul, 2013 | Pubmed ID: 23891991
Neutralizing antibodies against previously encountered influenza virus strains increase over time: a longitudinal analysis.
Science translational medicine Aug, 2013 | Pubmed ID: 23946196
Influenza virus hemagglutinin stalk-based antibodies and vaccines.
Current opinion in virology Oct, 2013 | Pubmed ID: 23978327
Guiding the immune response against influenza virus hemagglutinin toward the conserved stalk domain by hyper-glycosylation of the globular head domain.
Journal of virology Oct, 2013 | Pubmed ID: 24155380
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