Rohini Kuner

Importance of the gamma-aminobutyric acid(B) receptor C-termini for G-protein coupling.

Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.

Spinal upregulation of the nitric oxide synthase-interacting protein NOSIP in a rat model of inflammatory pain.

TorsinA protects against oxidative stress in COS-1 and PC12 cells.

TorsinA, the gene linked to early-onset dystonia, is upregulated by the dopaminergic toxin MPTP in mice.

Identification of regulated genes during permanent focal cerebral ischaemia: characterization of the protein kinase 9b5/MARKL1/MARK4.

Conditional gene deletion in primary nociceptive neurons of trigeminal ganglia and dorsal root ganglia.

Plexin-B family members demonstrate non-redundant expression patterns in the developing mouse nervous system: an anatomical basis for morphogenetic effects of Sema4D during development.

Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2.

The AMPA receptor subunits GluR-A and GluR-B reciprocally modulate spinal synaptic plasticity and inflammatory pain.

Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity.

Late-onset motoneuron disease caused by a functionally modified AMPA receptor subunit.

Mechanisms of disease: motoneuron disease aggravated by transgenic expression of a functionally modified AMPA receptor subunit.

Regulation of motor performance and striatal function by synaptic scaffolding proteins of the Homer1 family.

Synaptic scaffolding protein Homer1a protects against chronic inflammatory pain.

Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1.

A molecular basis of analgesic tolerance to cannabinoids.

Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis.

Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo.

Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors.

Mechanisms of compartmentalized expression of Mrg class G-protein-coupled sensory receptors.

Genetic deletion of synapsin II reduces neuropathic pain due to reduced glutamate but increased GABA in the spinal cord dorsal horn.

A functional role for semaphorin 4D/plexin B1 interactions in epithelial branching morphogenesis during organogenesis.

Activity-dependent potentiation of calcium signals in spinal sensory networks in inflammatory pain states.

Hematopoietic colony-stimulating factors mediate tumor-nerve interactions and bone cancer pain.

Roles of the AMPA receptor subunit GluA1 but not GluA2 in synaptic potentiation and activation of ERK in the anterior cingulate cortex.

Mice lacking Plexin-B3 display normal CNS morphology and behaviour.

The semaphorin 4D-plexin-B signalling complex regulates dendritic and axonal complexity in developing neurons via diverse pathways.

Inhibitor kappaB Kinase beta deficiency in primary nociceptive neurons increases TRP channel sensitivity.

A key role for gp130 expressed on peripheral sensory nerves in pathological pain.

Dissecting the functional significance of endothelin A receptors in peripheral nociceptors in vivo via conditional gene deletion.

Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo.

An improved behavioural assay demonstrates that ultrasound vocalizations constitute a reliable indicator of chronic cancer pain and neuropathic pain.

R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids.

Central mechanisms of pathological pain.

Hematopoietic colony-stimulating factors: new players in tumor-nerve interactions.

Genetic evidence for involvement of neuronally expressed S1P₁ receptor in nociceptor sensitization and inflammatory pain.

Follistatin-like 1 suppresses sensory afferent transmission by activating Na+,K+-ATPase.

Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice.

Homer1a signaling in the amygdala counteracts pain-related synaptic plasticity, mGluR1 function and pain behaviors.

Presynaptic alpha2-GABAA receptors in primary afferent depolarization and spinal pain control.

Gα(q/11) signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization.

Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity.

Dynamin 2 mutations in Charcot-Marie-Tooth neuropathy highlight the importance of clathrin-mediated endocytosis in myelination.

Pain in experimental autoimmune encephalitis: a comparative study between different mouse models.

Nuclear calcium signaling in spinal neurons drives a genomic program required for persistent inflammatory pain.

Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation.

Pain hypersensitivity mechanisms at a glance.

A novel biological role for the phospholipid lysophosphatidylinositol in nociceptive sensitization via activation of diverse G-protein signalling pathways in sensory nerves in vivo.

Genome-wide identification and functional analyses of microRNA signatures associated with cancer pain.

Transcriptional mechanisms underlying sensitization of peripheral sensory neurons by granulocyte-/granulocyte-macrophage colony stimulating factors.

microRNAs in nociceptive circuits as predictors of future clinical applications.

Gq rather than G11 preferentially mediates nociceptor sensitization.

BKCa channels expressed in sensory neurons modulate inflammatory pain in mice.

Genetic dissection of plexin signaling in vivo.

Sources of individual variability: miRNAs that predispose to neuropathic pain identified using genome-wide sequencing.