Institute for Pharmacology
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Importance of the gamma-aminobutyric acid(B) receptor C-termini for G-protein coupling.
Molecular pharmacology May, 2002 | Pubmed ID: 11961124
Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.
Neuron Jul, 2002 | Pubmed ID: 12123608
Spinal upregulation of the nitric oxide synthase-interacting protein NOSIP in a rat model of inflammatory pain.
Neuroscience letters Oct, 2003 | Pubmed ID: 12962906
TorsinA protects against oxidative stress in COS-1 and PC12 cells.
Neuroscience letters Oct, 2003 | Pubmed ID: 14550917
TorsinA, the gene linked to early-onset dystonia, is upregulated by the dopaminergic toxin MPTP in mice.
Neuroscience letters Jan, 2004 | Pubmed ID: 14729251
Identification of regulated genes during permanent focal cerebral ischaemia: characterization of the protein kinase 9b5/MARKL1/MARK4.
Journal of neurochemistry Mar, 2004 | Pubmed ID: 15009667
Conditional gene deletion in primary nociceptive neurons of trigeminal ganglia and dorsal root ganglia.
Genesis (New York, N.Y. : 2000) Mar, 2004 | Pubmed ID: 15048809
Plexin-B family members demonstrate non-redundant expression patterns in the developing mouse nervous system: an anatomical basis for morphogenetic effects of Sema4D during development.
The European journal of neuroscience May, 2004 | Pubmed ID: 15147296
Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2.
The Journal of cell biology Jun, 2004 | Pubmed ID: 15210733
The AMPA receptor subunits GluR-A and GluR-B reciprocally modulate spinal synaptic plasticity and inflammatory pain.
Neuron Nov, 2004 | Pubmed ID: 15541312
Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2004 | Pubmed ID: 15548660
Late-onset motoneuron disease caused by a functionally modified AMPA receptor subunit.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2005 | Pubmed ID: 15827116
Mechanisms of disease: motoneuron disease aggravated by transgenic expression of a functionally modified AMPA receptor subunit.
Annals of the New York Academy of Sciences Aug, 2005 | Pubmed ID: 16179532
Regulation of motor performance and striatal function by synaptic scaffolding proteins of the Homer1 family.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2006 | Pubmed ID: 16407107
Synaptic scaffolding protein Homer1a protects against chronic inflammatory pain.
Nature medicine Jun, 2006 | Pubmed ID: 16715092
Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2007 | Pubmed ID: 17194758
A molecular basis of analgesic tolerance to cannabinoids.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2007 | Pubmed ID: 17428994
Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis.
Gastroenterology May, 2007 | Pubmed ID: 17484889
Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2007 | Pubmed ID: 17554007
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors.
Nature neuroscience Jul, 2007 | Pubmed ID: 17558404
Mechanisms of compartmentalized expression of Mrg class G-protein-coupled sensory receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2008 | Pubmed ID: 18171930
Genetic deletion of synapsin II reduces neuropathic pain due to reduced glutamate but increased GABA in the spinal cord dorsal horn.
Pain Oct, 2008 | Pubmed ID: 18701217
A functional role for semaphorin 4D/plexin B1 interactions in epithelial branching morphogenesis during organogenesis.
Development (Cambridge, England) Oct, 2008 | Pubmed ID: 18799546
Activity-dependent potentiation of calcium signals in spinal sensory networks in inflammatory pain states.
Pain Nov, 2008 | Pubmed ID: 18926636
Hematopoietic colony-stimulating factors mediate tumor-nerve interactions and bone cancer pain.
Nature medicine Jul, 2009 | Pubmed ID: 19525966
Roles of the AMPA receptor subunit GluA1 but not GluA2 in synaptic potentiation and activation of ERK in the anterior cingulate cortex.
Molecular pain , 2009 | Pubmed ID: 19664265
Mice lacking Plexin-B3 display normal CNS morphology and behaviour.
Molecular and cellular neurosciences Dec, 2009 | Pubmed ID: 19699796
The semaphorin 4D-plexin-B signalling complex regulates dendritic and axonal complexity in developing neurons via diverse pathways.
The European journal of neuroscience Oct, 2009 | Pubmed ID: 19788569
Inhibitor kappaB Kinase beta deficiency in primary nociceptive neurons increases TRP channel sensitivity.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2009 | Pubmed ID: 19828806
A key role for gp130 expressed on peripheral sensory nerves in pathological pain.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2009 | Pubmed ID: 19864560
Dissecting the functional significance of endothelin A receptors in peripheral nociceptors in vivo via conditional gene deletion.
Pain Feb, 2010 | Pubmed ID: 19879049
Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo.
Molecular pain , 2009 | Pubmed ID: 19925671
An improved behavioural assay demonstrates that ultrasound vocalizations constitute a reliable indicator of chronic cancer pain and neuropathic pain.
Molecular pain , 2010 | Pubmed ID: 20346101
R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids.
PloS one , 2010 | Pubmed ID: 20498712
Central mechanisms of pathological pain.
Nature medicine Nov, 2010 | Pubmed ID: 20948531
Hematopoietic colony-stimulating factors: new players in tumor-nerve interactions.
Journal of molecular medicine (Berlin, Germany) Apr, 2011 | Pubmed ID: 21079906
Genetic evidence for involvement of neuronally expressed S1P₁ receptor in nociceptor sensitization and inflammatory pain.
PloS one , 2011 | Pubmed ID: 21359147
Follistatin-like 1 suppresses sensory afferent transmission by activating Na+,K+-ATPase.
Neuron Mar, 2011 | Pubmed ID: 21382556
Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice.
The Journal of clinical investigation Apr, 2011 | Pubmed ID: 21383497
Homer1a signaling in the amygdala counteracts pain-related synaptic plasticity, mGluR1 function and pain behaviors.
Molecular pain , 2011 | Pubmed ID: 21595930
Presynaptic alpha2-GABAA receptors in primary afferent depolarization and spinal pain control.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2011 | Pubmed ID: 21632935
Gα(q/11) signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization.
Pain Jan, 2012 | Pubmed ID: 22071319
Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity.
PLoS biology , 2012 | Pubmed ID: 22427743
Dynamin 2 mutations in Charcot-Marie-Tooth neuropathy highlight the importance of clathrin-mediated endocytosis in myelination.
Brain : a journal of neurology May, 2012 | Pubmed ID: 22451505
Pain in experimental autoimmune encephalitis: a comparative study between different mouse models.
Journal of neuroinflammation , 2012 | Pubmed ID: 23039175
Nuclear calcium signaling in spinal neurons drives a genomic program required for persistent inflammatory pain.
Neuron Jan, 2013 | Pubmed ID: 23312515
Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation.
Journal of immunology (Baltimore, Md. : 1950) May, 2013 | Pubmed ID: 23585676
Pain hypersensitivity mechanisms at a glance.
Disease models & mechanisms Jul, 2013 | Pubmed ID: 23828645
A novel biological role for the phospholipid lysophosphatidylinositol in nociceptive sensitization via activation of diverse G-protein signalling pathways in sensory nerves in vivo.
Pain Dec, 2013 | Pubmed ID: 23973358
Genome-wide identification and functional analyses of microRNA signatures associated with cancer pain.
EMBO molecular medicine Nov, 2013 | Pubmed ID: 24039159
Transcriptional mechanisms underlying sensitization of peripheral sensory neurons by granulocyte-/granulocyte-macrophage colony stimulating factors.
Molecular pain , 2013 | Pubmed ID: 24067145
microRNAs in nociceptive circuits as predictors of future clinical applications.
Frontiers in molecular neuroscience , 2013 | Pubmed ID: 24151455
Gq rather than G11 preferentially mediates nociceptor sensitization.
Molecular pain , 2013 | Pubmed ID: 24156378
BKCa channels expressed in sensory neurons modulate inflammatory pain in mice.
Pain Mar, 2014 | Pubmed ID: 24333777
Genetic dissection of plexin signaling in vivo.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2014 | Pubmed ID: 24469813
Sources of individual variability: miRNAs that predispose to neuropathic pain identified using genome-wide sequencing.
Molecular pain Mar, 2014 | Pubmed ID: 24642266