Department of Neuroscience,
Center for Translational Research in Neurodegenerative Disease,
Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease
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Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-kappaB) activation and cell death by tea extracts in neuronal cultures.
Biochemical pharmacology Jan, 2002 | Pubmed ID: 11754870
Involvement of protein kinase C activation and cell survival/ cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action.
The Journal of biological chemistry Aug, 2002 | Pubmed ID: 12058035
Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology May, 2003 | Pubmed ID: 12670874
Early and late molecular events in neurodegeneration and neuroprotection in Parkinson's disease MPTP model as assessed by cDNA microarray; the role of iron.
Neurotoxicity research Nov-Dec, 2002 | Pubmed ID: 12709306
Neuroprotective strategies in Parkinson's disease : an update on progress.
CNS drugs , 2003 | Pubmed ID: 12873156
Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model.
The Journal of clinical investigation Jan, 2006 | Pubmed ID: 16341263
Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Abeta immunotherapy.
Journal of neuroinflammation , 2006 | Pubmed ID: 16872492
Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Dec, 2006 | Pubmed ID: 17068112
Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor protein mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2006 | Pubmed ID: 17108166
Rab5 mediates an amyloid precursor protein signaling pathway that leads to apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2007 | Pubmed ID: 17611268
BRI2 (ITM2b) inhibits Abeta deposition in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2008 | Pubmed ID: 18524908
Quantitative and mechanistic studies of Abeta immunotherapy.
CNS & neurological disorders drug targets Mar, 2009 | Pubmed ID: 19275635
Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease.
Molecular therapy : the journal of the American Society of Gene Therapy Dec, 2009 | Pubmed ID: 19638957
Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Feb, 2010 | Pubmed ID: 19825975
Inhibiting β-secretase activity in Alzheimer's disease cell models with single-chain antibodies specifically targeting APP.
Journal of molecular biology Jan, 2011 | Pubmed ID: 21073877
Bispecific tandem single chain antibody simultaneously inhibits β-secretase and promotes α-secretase processing of AβPP.
Journal of Alzheimer's disease : JAD , 2012 | Pubmed ID: 22156046
Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains.
Alzheimer's research & therapy , 2012 | Pubmed ID: 22621179
Aβ alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo.
Nature communications , 2012 | Pubmed ID: 22910355
Viral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuits in vivo.
The European journal of neuroscience Apr, 2013 | Pubmed ID: 23347239
Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy.
Acta neuropathologica Jul, 2013 | Pubmed ID: 23666556
Capsid serotype and timing of injection determines AAV transduction in the neonatal mice brain.
PloS one , 2013 | Pubmed ID: 23825679
Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein.
Acta neuropathologica communications , 2013 | Pubmed ID: 24252149
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