Christina Chan

Metabolic pre-conditioning of cultured cells in physiological levels of insulin: generating resistance to the lipid-accumulating effects of plasma in hepatocytes.

Inverse relationship between six week postvaccination varicella antibody response to vaccine and likelihood of long term breakthrough infection.

A comparison of safety, tolerability and immunogenicity of Oka/Merck varicella vaccine and VARILRIX in healthy children.

Vaccination with measles, mumps and rubella vaccine and varicella vaccine: safety, tolerability, immunogenicity, persistence of antibody and duration of protection against varicella in healthy children.

Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation.

Use of statistical models for evaluating antibody response as a correlate of protection against varicella.

Metabolic flux analysis of cultured hepatocytes exposed to plasma.

Varicella vaccination in children with chronic renal failure. A report of the Southwest Pediatric Nephrology Study Group.

Varicella vaccination in children with nephrotic syndrome: a report of the Southwest Pediatric Nephrology Study Group.

Measurement of cell-mediated immunity with a Varicella-Zoster Virus-specific interferon-gamma ELISPOT assay: responses in an elderly population receiving a booster immunization.

Application of multivariate analysis to optimize function of cultured hepatocytes.

Metabolic flux analysis of hepatocyte function in hormone- and amino acid-supplemented plasma.

Direct extraction of Sabin poliovirus genomes from human fecal samples using a guanidine thiocyanate extraction method.

Splinter removal.

Decline in varicella-zoster virus (VZV)-specific cell-mediated immunity with increasing age and boosting with a high-dose VZV vaccine.

Inferring pathways and networks with a Bayesian framework.

Inverse modeling using multi-block PLS to determine the environmental conditions that provide optimal cellular function.

Concomitant administration of a bivalent Haemophilus influenzae type b-hepatitis B vaccine, measles-mumps-rubella vaccine and varicella vaccine: safety, tolerability and immunogenicity.

Selective depositions on polyelectrolyte multilayers: self-assembled monolayers of m-dPEG acid as molecular template.

Integrating gene expression and metabolic profiles.

Shedding of sabin poliovirus Type 3 containing the nucleotide 472 uracil-to-cytosine point mutation after administration of oral poliovirus vaccine.

Extracting novel information from gene expression data.

Hepatic tissue engineering for adjunct and temporary liver support: critical technologies.

Controlling primary hepatocyte adhesion and spreading on protein-free polyelectrolyte multilayer films.

Insulin concentration during preconditioning mediates the regulation of urea synthesis during exposure to amino acid-supplemented plasma.

Palmitic and stearic fatty acids induce Alzheimer-like hyperphosphorylation of tau in primary rat cortical neurons.

Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis.

Using a state-space model with hidden variables to infer transcription factor activities.

Efficacy and safety of ertapenem versus piperacillin-tazobactam for the treatment of intra-abdominal infections requiring surgical intervention.

Palmitic acid-treated astrocytes induce BACE1 upregulation and accumulation of C-terminal fragment of APP in primary cortical neurons.

Safety, tolerability, and immunogenicity of a two-dose regimen of high-titer varicella vaccine in subjects > or =13 years of age.

Cellular to tissue informatics: approaches to optimizing cellular function of engineered tissue.

Hydrogen peroxide and hydroxyl radicals mediate palmitate-induced cytotoxicity to hepatoma cells: relation to mitochondrial permeability transition.

Sirolimus blocks the accumulation of hyaluronan (HA) by arterial smooth muscle cells and reduces monocyte adhesion to the ECM.

Interleukin-1beta selectively decreases the synthesis of versican by arterial smooth muscle cells.

Barriers and missed opportunities in breast and cervical cancer screening among women aged 50 and over, New York City, 2002.

Patterned co-culture of primary hepatocytes and fibroblasts using polyelectrolyte multilayer templates.

A modified polymerase chain reaction-long serial analysis of gene expression protocol identifies novel transcripts in human CD34+ bone marrow cells.

Ertapenem versus ceftriaxone and metronidazole as treatment for complicated intra-abdominal infections.

A hierarchical approach employing metabolic and gene expression profiles to identify the pathways that confer cytotoxicity in HepG2 cells.

Bowel colonization with vancomycin-resistant enterococci after antimicrobial therapy for intra-abdominal infections: observations from 2 randomized comparative clinical trials of ertapenem therapy.

Cell adhesion on polyelectrolyte multilayer coated polydimethylsiloxane surfaces with varying topographies.

Adipocyte-derived serum amyloid A3 and hyaluronan play a role in monocyte recruitment and adhesion.

A Three Stage Integrative Pathway Search (TIPS) framework to identify toxicity relevant genes and pathways.

Signal transducer and activator of transcription 3 is involved in cell growth and survival of human rhabdomyosarcoma and osteosarcoma cells.

Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line.

Cholesterol-lowering ability of a phytostanol softgel supplement in adults with mild to moderate hypercholesterolemia.

Involvement of astroglial ceramide in palmitic acid-induced Alzheimer-like changes in primary neurons.

Identification of genes that regulate multiple cellular processes/responses in the context of lipotoxicity to hepatoma cells.

A knowledge driven regression model for gene expression and microarray analysis.

Tunable resistive m-dPEG acid patterns on polyelectrolyte multilayers at physiological conditions: template for directed deposition of biomacromolecules.

Using dynamic gene module map analysis to identify targets that modulate free fatty acid induced cytotoxicity.

Previous cancer screening behavior as predictor of endoscopic colon cancer screening among women aged 50 and over, in NYC 2002.

Experimental and computational studies investigating trehalose protection of HepG2 cells from palmitate-induced toxicity.

Sampling and recruitment in multilevel studies among marginalized urban populations: the IMPACT studies.

Short time-series microarray analysis: methods and challenges.

Stress-associated hormone, norepinephrine, increases proliferation and IL-6 levels of human pancreatic duct epithelial cells and can be inhibited by the dietary agent, sulforaphane.

Combinatorial surrobody libraries.

Brain region-specificity of palmitic acid-induced abnormalities associated with Alzheimer's disease.

Gene module level analysis: identification to networks and dynamics.

Athsq1 is an atherosclerosis modifier locus with dramatic effects on lesion area and prominent accumulation of versican.

The accumulation of versican in the nodules of benign prostatic hyperplasia.

Signal transducer and activator of transcription 3 activation is associated with bladder cancer cell growth and survival.

Correlates of illicit methadone use in New York City: a cross-sectional study.

A Bayesian framework for knowledge driven regression model in micro-array data analysis.

A novel method incorporating gene ontology information for unsupervised clustering and feature selection.

Multilayer mediated forward and patterned siRNA transfection using linear-PEI at extended N/P ratios.

Repression of PKR mediates palmitate-induced apoptosis in HepG2 cells through regulation of Bcl-2.

Systems biology for identifying liver toxicity pathways.

Culture clash: a missed opportunity.

The role of fatty acid unsaturation in minimizing biophysical changes on the structure and local effects of bilayer membranes.

Reconstruct modular phenotype-specific gene networks by knowledge-driven matrix factorization.

Endo-laparoscopic reduction and resection of gastroduodenal intussuception of gastrointestinal stromal tumor (GIST): a synchronous endoscopic and laparoscopic treatment.

Polyinosine-polycytidylic acid stimulates versican accumulation in the extracellular matrix promoting monocyte adhesion.

Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation.

A dynamic analysis of IRS-PKR signaling in liver cells: a discrete modeling approach.

Synergistic effect of cAMP and palmitate in promoting altered mitochondrial function and cell death in HepG2 cells.

Synthesis and organization of hyaluronan and versican by embryonic stem cells undergoing embryoid body differentiation.

Platelet-derived growth factor differentially regulates the expression and post-translational modification of versican by arterial smooth muscle cells through distinct protein kinase C and extracellular signal-regulated kinase pathways.

Intimate partner violence perpetration and condom use-related factors: associations with heterosexual men's consistent condom use.

Recognition of siRNA asymmetry by TAR RNA binding protein.

Time Controlled Protein Release from Layer-by-Layer Assembled Multilayer Functionalized Agarose Hydrogels.

Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse.

Cancer-drug associations: a complex system.

Culture clash: a missed opportunity.

Withanolide A and asiatic acid modulate multiple targets associated with amyloid-beta precursor protein processing and amyloid-beta protein clearance.

Differentiation of cardiomyocytes from human embryonic stem cells is accompanied by changes in the extracellular matrix production of versican and hyaluronan.

Cell adhesive behavior on thin polyelectrolyte multilayers: cells attempt to achieve homeostasis of its adhesion energy.

The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cells.

cAMP initiates early phase neuron-like morphology changes and late phase neural differentiation in mesenchymal stem cells.

Confocal microscopy for the analysis of siRNA delivery by polymeric nanoparticles.

Designing highly active siRNAs for therapeutic applications.

Integrative analysis of cancer pathway progression and coherence.

Molecular mechanism by which palmitate inhibits PKR autophosphorylation.

Time controlled release of arabinofuranosylcytosine (Ara-C) from agarose hydrogels using layer-by-layer assembly: an in vitro study.

Proteolytic cleavage of versican and involvement of ADAMTS-1 in VEGF-A/VPF-induced pathological angiogenesis.

Cholera, canals, and contagion: Rediscovering Dr. Beck's report.

Learning transcriptional regulation on a genome scale: a theoretical analysis based on gene expression data.

POLYELECTROLYTE MULTILAYER STAMPING IN AQUEOUS PHASE AND NON-CONTACT MODE.

MicroRNA-137/181c regulates serine palmitoyltransferase and in turn amyloid β, novel targets in sporadic Alzheimer's disease.

Identification of novel targets for breast cancer by exploring gene switches on a genome scale.

A case of recurrent earthquake stress cardiomyopathy with a differing wall motion abnormality.

Synergy analysis reveals association between insulin signaling and desmoplakin expression in palmitate treated HepG2 cells.

Blood serum miRNA: Non-invasive biomarkers for Alzheimer's disease.

Core groups, antimicrobial resistance and rebound in gonorrhoea in North America.

Monocyte-to-macrophage differentiation: synthesis and secretion of a complex extracellular matrix.

Evaluating New York City's smoke-free parks and beaches law: a critical multiplist approach to assessing behavioral impact.

Palmitate-activated astrocytes via serine palmitoyltransferase increase BACE1 in primary neurons by sphingomyelinases.

Awareness and impact of New York City's graphic point-of-sale tobacco health warning signs.

Overall sulfation of heparan sulfate from pancreatic islet β-TC3 cells increases maximal fibril formation but does not determine binding to the amyloidogenic peptide islet amyloid polypeptide.

Latest developments in experimental and computational approaches to characterize protein-lipid interactions.

Cleavage of hyaluronan is impaired in aged dermal wounds.

Pooling Expressed Breastmilk to Provide a Consistent Feeding Composition for Premature Infants.

Oligomerization of the transmembrane domain of IRE1α in SDS micelles.

Effectiveness and cost-effectiveness of pediatric rotavirus vaccination in British Columbia: a model-based evaluation.

Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells.

Global protein phosphorylation dynamics during deoxynivalenol-induced ribotoxic stress response in the macrophage.

Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults.

Quantitative, solution-phase profiling of multiple transcription factors in parallel.

Inhibition of serine palmitoyltransferase reduces Aβ and tau hyperphosphorylation in a murine model: a safe therapeutic strategy for Alzheimer's disease.

Chronic back problems and labor force participation in a national population survey: impact of comorbid arthritis.

The impact of cigarette excise tax increases on purchasing behaviors among New York city smokers.

A multi-layer inference approach to reconstruct condition-specific genes and their regulation.

A classification framework applied to cancer gene expression profiles.

Early phosphoproteomic changes in the mouse spleen during deoxynivalenol-induced ribotoxic stress.

Acute myocardial infarction and stress cardiomyopathy following the Christchurch earthquakes.

Human milk galectin-3 binding protein and breast-feeding-associated HIV transmission.

ENDOCYTOSIS PATHWAYS FOR NUCLEIC ACID THERAPEUTICS.

Palmitate induces transcriptional regulation of BACE1 and presenilin by STAT3 in neurons mediated by astrocytes.

A prospective, assessor-blind evaluation of surgeon-performed transcutaneous laryngeal ultrasonography in vocal cord examination before and after thyroidectomy.

Design of siRNA Therapeutics from the Molecular Scale.

Historical epidemiology of the second cholera pandemic: relevance to present day disease dynamics.

Challenges in the practice of human milk nutrition in the neonatal intensive care unit.

Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons.

ADAMTS-4 and biglycan are expressed at high levels and co-localize to podosomes during endothelial cell tubulogenesis in vitro.

IPAF inflammasome is involved in interleukin-1β production from astrocytes, induced by palmitate; implications for Alzheimer's Disease.

Association between Mycoplasma-specific polymerase chain reaction assay results and oral bacterial contamination of bronchoalveolar lavage fluid samples from dogs with respiratory tract disease: 121 cases (2005-2012).

Is vocal cord asymmetry seen on transcutaneous laryngeal ultrasonography a significant predictor of voice quality changes after thyroidectomy?

Public opinions on tax and retail-based tobacco control strategies.

Improved asymmetry prediction for short interfering RNAs.

Prediction of therapeutic microRNA based on the human metabolic network.

A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease.

Augmenting protein release from layer-by-layer functionalized agarose hydrogels.

The role of inflammasome in Alzheimer's disease.

Systematic modeling for the insulin signaling network mediated by IRS(1) and IRS(2).

Reprint of: A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease.

Binding site multiplicity with fatty acid ligands: implications for the regulation of PKR kinase autophosphorylation with palmitate.

Human metabolic network: reconstruction, simulation, and applications in systems biology.

One-year follow-up of the 2011 Christchurch Earthquake stress cardiomyopathy cases.

Hyaluronan in aged collagen matrix increases prostate epithelial cell proliferation.

CREB modulates calcium signaling in cAMP-induced bone marrow stromal cells (BMSCs).

Ensemble Classification of Cancer Types and Biomarker Identification.

Detection of Glaucoma and Its Association With Diabetic Retinopathy in a Diabetic Retinopathy Screening Program.

Hospital admission for community-acquired pneumonia in a First Nations population.

The detection of glycosaminoglycans in pancreatic islets and lymphoid tissues.

Primary Neuron/Astrocyte Co-Culture on Polyelectrolyte Multilayer Films: A Template for Studying Astrocyte-Mediated Oxidative Stress in Neurons.

The impact of lack of government-insured routine eye examinations on the incidence of self-reported glaucoma, cataracts, and vision loss.

Brain derived neurotrophic factor release from layer-by-layer coated agarose nerve guidance scaffolds.

Pharmacologic evaluation of ammonium tetrathiomolybdate after intravenous and oral administration to healthy dogs.

Polymeric Micelle-Mediated Delivery of DNA-Targeting Organometallic Complexes for Resistant Ovarian Cancer Treatment.

Nanomedicine for Combination Therapy of Cancer.

Systematic screening for diabetic retinopathy (DR) in Hong Kong: prevalence of DR and visual impairment among diabetic population.

Rapid fine conformational epitope mapping using comprehensive mutagenesis and deep sequencing.

Cost-Effectiveness of Screening for Intermediate Age-Related Macular Degeneration during Diabetic Retinopathy Screening.

How can novel microscopic approaches shed light on the function of nucleic acid-based drugs?

Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma.

The Impact of Prestretch Induced Surface Anisotropy on Axon Regeneration.

The impact of a co-payment on the cost-effectiveness of screening for diabetic retinopathy.

Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers.

Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing.

Does classroom-based crew resource management training have an effect on attitudes between doctors and nurses?

Nanoscale Coordination Polymers Codeliver Chemotherapeutics and siRNAs to Eradicate Tumors of Cisplatin-Resistant Ovarian Cancer.

Schwann Cells Migration on Patterned Polydimethylsiloxane Microgrooved Surface.

Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy.