Yoshihiro Urade

Activation of adipogenesis by lipocalin-type prostaglandin D synthase-generated Δ¹²-PGJ₂ acting through PPARγ-dependent and independent pathways.

Orally administered rubiscolin-6, a δ opioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocallin-type prostaglandin D synthase in mice.

Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, induces sleep via the benzodiazepine site of GABA(A) receptor in mice.

Lipocalin prostaglandin D synthase and PPARγ2 coordinate to regulate carbohydrate and lipid metabolism in vivo.

[Endogenous sleep-promoting substance].

How do the basal ganglia regulate sleep-wake behavior?

A new role for lipocalin prostaglandin d synthase in the regulation of brown adipose tissue substrate utilization.

Proteomic analysis of cerebrospinal fluid before and after intrathecal injection of steroid into patients with postherpetic pain.

PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis.

Dopamine is involved in food-anticipatory activity in mice.

The role of nucleus accumbens core/shell in sleep-wake regulation and their involvement in modafinil-induced arousal.

Unilateral cryptorchidism in mice mutant for Ptgds.

The lipocalin-type prostaglandin D2 synthase knockout mouse model of insulin resistance and obesity demonstrates early hypothalamic-pituitary-adrenal axis hyperactivity.

A urine biomarker for severe obstructive sleep apnoea patients: lipocalin-type prostaglandin D synthase.

Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier.

Morphine inhibits sleep-promoting neurons in the ventrolateral preoptic area via mu receptors and induces wakefulness in rats.

Mast cells contribute to double-stranded RNA-induced augmentation of airway eosinophilia in a murine model of asthma.

Crystal structure of a Bombyx mori sigma-class glutathione transferase exhibiting prostaglandin E synthase activity.

Role of the basal ganglia in the control of sleep and wakefulness.

Anti-inflammatory role of PGD2 in acute lung inflammation and therapeutic application of its signal enhancement.

A prostaglandin D2 metabolite is elevated in the urine of Duchenne muscular dystrophy patients and increases further from 8 years old.

FASTER: an unsupervised fully automated sleep staging method for mice.

Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.

Elevated CSF histamine levels in multiple sclerosis patients.

Bofutsushosan, a Japanese herbal (Kampo) medicine, attenuates progression of nonalcoholic steatohepatitis in mice.

GABA transporter-1 inhibitor NO-711 alters the EEG power spectra and enhances non-rapid eye movement sleep during the active phase in mice.

Endogenous prostaglandin D2 and its metabolites protect the heart against ischemia-reperfusion injury by activating Nrf2.

Roles of adrenergic α1 and dopamine D1 and D2 receptors in the mediation of the desynchronization effects of modafinil in a mouse EEG synchronization model.

New insights into the catalytic mechanism of Bombyx mori prostaglandin E synthase gained from structure-function analysis.

Essential roles of GABA transporter-1 in controlling rapid eye movement sleep and in increased slow wave activity after sleep deprivation.

Opposing immunomodulatory roles of prostaglandin D2 during the progression of skin inflammation.

A mouse model mimicking human first night effect for the evaluation of hypnotics.

Prostaglandin D(2) is crucial for seizure suppression and postictal sleep.

δ-Opioid receptor activation stimulates normal diet intake but conversely suppresses high-fat diet intake in mice.

Projections of nucleus accumbens adenosine A2A receptor neurons in the mouse brain and their implications in mediating sleep-wake regulation.

Marine polyphenol phlorotannins promote non-rapid eye movement sleep in mice via the benzodiazepine site of the GABAA receptor.

Practical evaluation of liquid chromatography/tandem mass spectrometry and enzyme immunoassay method for the accurate quantitative analysis of prostaglandins.

Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells.

Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain.

Intestinal tumor suppression in ApcMin/+ mice by prostaglandin D2 receptor PTGDR.

Association of lipocalin-type prostaglandin D synthase with disproportionately enlarged subarachnoid-space in idiopathic normal pressure hydrocephalus.

Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products.

Mast cell-derived prostaglandin D2 inhibits colitis and colitis-associated colon cancer in mice.

Transcriptional regulation in adipogenesis through PPARγ-dependent and -independent mechanisms by prostaglandins.

Lipocalin-type prostaglandin D synthase scavenges biliverdin in the cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage.

Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis.

Acid reflux directly causes sleep disturbances in rat with chronic esophagitis.

Prostaglandin D2 synthase/GPR44: a signaling axis in PNS myelination.

Doxepin and diphenhydramine increased non-rapid eye movement sleep through blockade of histamine H1 receptors.

The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep.

Zinc-containing yeast extract promotes nonrapid eye movement sleep in mice.

PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia.

Japanese sake yeast supplementation improves the quality of sleep: a double-blind randomised controlled clinical trial.