International Institute for Integrative Sleep Medicine (WPI-IIIS)
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Activation of adipogenesis by lipocalin-type prostaglandin D synthase-generated Δ¹²-PGJ₂ acting through PPARγ-dependent and independent pathways.
Gene Aug, 2012 | Pubmed ID: 22664386
Orally administered rubiscolin-6, a δ opioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocallin-type prostaglandin D synthase in mice.
Molecular nutrition & food research Aug, 2012 | Pubmed ID: 22715053
Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, induces sleep via the benzodiazepine site of GABA(A) receptor in mice.
Neuropharmacology Nov, 2012 | Pubmed ID: 22771461
Lipocalin prostaglandin D synthase and PPARγ2 coordinate to regulate carbohydrate and lipid metabolism in vivo.
PloS one , 2012 | Pubmed ID: 22792179
[Endogenous sleep-promoting substance].
Nihon rinsho. Japanese journal of clinical medicine Jul, 2012 | Pubmed ID: 22844810
How do the basal ganglia regulate sleep-wake behavior?
Trends in neurosciences Dec, 2012 | Pubmed ID: 22858523
A new role for lipocalin prostaglandin d synthase in the regulation of brown adipose tissue substrate utilization.
Diabetes Dec, 2012 | Pubmed ID: 22923471
Proteomic analysis of cerebrospinal fluid before and after intrathecal injection of steroid into patients with postherpetic pain.
Proteomics Oct, 2012 | Pubmed ID: 22936653
PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis.
Journal of the American Society of Nephrology : JASN Nov, 2012 | Pubmed ID: 22997255
Dopamine is involved in food-anticipatory activity in mice.
Journal of biological rhythms Oct, 2012 | Pubmed ID: 23010662
The role of nucleus accumbens core/shell in sleep-wake regulation and their involvement in modafinil-induced arousal.
PloS one , 2012 | Pubmed ID: 23029032
Unilateral cryptorchidism in mice mutant for Ptgds.
Human mutation Feb, 2013 | Pubmed ID: 23076868
The lipocalin-type prostaglandin D2 synthase knockout mouse model of insulin resistance and obesity demonstrates early hypothalamic-pituitary-adrenal axis hyperactivity.
The Journal of endocrinology Feb, 2013 | Pubmed ID: 23151358
A urine biomarker for severe obstructive sleep apnoea patients: lipocalin-type prostaglandin D synthase.
The European respiratory journal Dec, 2013 | Pubmed ID: 23222881
Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier.
Drug metabolism and disposition: the biological fate of chemicals Apr, 2013 | Pubmed ID: 23298861
Morphine inhibits sleep-promoting neurons in the ventrolateral preoptic area via mu receptors and induces wakefulness in rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Apr, 2013 | Pubmed ID: 23303062
Mast cells contribute to double-stranded RNA-induced augmentation of airway eosinophilia in a murine model of asthma.
Respiratory research , 2013 | Pubmed ID: 23452625
Crystal structure of a Bombyx mori sigma-class glutathione transferase exhibiting prostaglandin E synthase activity.
Biochimica et biophysica acta Jun, 2013 | Pubmed ID: 23458683
Role of the basal ganglia in the control of sleep and wakefulness.
Current opinion in neurobiology Oct, 2013 | Pubmed ID: 23465424
Anti-inflammatory role of PGD2 in acute lung inflammation and therapeutic application of its signal enhancement.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2013 | Pubmed ID: 23479612
A prostaglandin D2 metabolite is elevated in the urine of Duchenne muscular dystrophy patients and increases further from 8 years old.
Clinica chimica acta; international journal of clinical chemistry Aug, 2013 | Pubmed ID: 23603101
FASTER: an unsupervised fully automated sleep staging method for mice.
Genes to cells : devoted to molecular & cellular mechanisms Jun, 2013 | Pubmed ID: 23621645
Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.
Nature immunology Jun, 2013 | Pubmed ID: 23624557
Elevated CSF histamine levels in multiple sclerosis patients.
Fluids and barriers of the CNS , 2013 | Pubmed ID: 23659456
Bofutsushosan, a Japanese herbal (Kampo) medicine, attenuates progression of nonalcoholic steatohepatitis in mice.
Journal of gastroenterology Jun, 2014 | Pubmed ID: 23800945
GABA transporter-1 inhibitor NO-711 alters the EEG power spectra and enhances non-rapid eye movement sleep during the active phase in mice.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology Apr, 2014 | Pubmed ID: 24080505
Endogenous prostaglandin D2 and its metabolites protect the heart against ischemia-reperfusion injury by activating Nrf2.
Hypertension Jan, 2014 | Pubmed ID: 24101662
Roles of adrenergic α1 and dopamine D1 and D2 receptors in the mediation of the desynchronization effects of modafinil in a mouse EEG synchronization model.
PloS one , 2013 | Pubmed ID: 24116090
New insights into the catalytic mechanism of Bombyx mori prostaglandin E synthase gained from structure-function analysis.
Biochemical and biophysical research communications Nov, 2013 | Pubmed ID: 24120949
Essential roles of GABA transporter-1 in controlling rapid eye movement sleep and in increased slow wave activity after sleep deprivation.
PloS one , 2013 | Pubmed ID: 24155871
Opposing immunomodulatory roles of prostaglandin D2 during the progression of skin inflammation.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2014 | Pubmed ID: 24298012
A mouse model mimicking human first night effect for the evaluation of hypnotics.
Pharmacology, biochemistry, and behavior Jan, 2014 | Pubmed ID: 24316349
Prostaglandin D(2) is crucial for seizure suppression and postictal sleep.
Experimental neurology Mar, 2014 | Pubmed ID: 24333565
δ-Opioid receptor activation stimulates normal diet intake but conversely suppresses high-fat diet intake in mice.
American journal of physiology. Regulatory, integrative and comparative physiology Feb, 2014 | Pubmed ID: 24401991
Projections of nucleus accumbens adenosine A2A receptor neurons in the mouse brain and their implications in mediating sleep-wake regulation.
Frontiers in neuroanatomy , 2013 | Pubmed ID: 24409122
Marine polyphenol phlorotannins promote non-rapid eye movement sleep in mice via the benzodiazepine site of the GABAA receptor.
Psychopharmacology Jul, 2014 | Pubmed ID: 24488362
Practical evaluation of liquid chromatography/tandem mass spectrometry and enzyme immunoassay method for the accurate quantitative analysis of prostaglandins.
Journal of bioscience and bioengineering Jul, 2014 | Pubmed ID: 24534197
Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells.
eLife , 2014 | Pubmed ID: 24668173
Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain.
Psychopharmacology Oct, 2014 | Pubmed ID: 24700387
Intestinal tumor suppression in ApcMin/+ mice by prostaglandin D2 receptor PTGDR.
Cancer medicine Aug, 2014 | Pubmed ID: 24729479
Association of lipocalin-type prostaglandin D synthase with disproportionately enlarged subarachnoid-space in idiopathic normal pressure hydrocephalus.
Fluids and barriers of the CNS , 2014 | Pubmed ID: 24731502
Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products.
Forensic science international Oct, 2014 | Pubmed ID: 24769262
Mast cell-derived prostaglandin D2 inhibits colitis and colitis-associated colon cancer in mice.
Cancer research Jun, 2014 | Pubmed ID: 24879565
Transcriptional regulation in adipogenesis through PPARγ-dependent and -independent mechanisms by prostaglandins.
Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 24927844
Lipocalin-type prostaglandin D synthase scavenges biliverdin in the cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Sep, 2014 | Pubmed ID: 25005874
Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis.
Development (Cambridge, England) Sep, 2014 | Pubmed ID: 25142465
Acid reflux directly causes sleep disturbances in rat with chronic esophagitis.
PloS one , 2014 | Pubmed ID: 25215524
Prostaglandin D2 synthase/GPR44: a signaling axis in PNS myelination.
Nature neuroscience Dec, 2014 | Pubmed ID: 25362470
Doxepin and diphenhydramine increased non-rapid eye movement sleep through blockade of histamine H1 receptors.
Pharmacology, biochemistry, and behavior Feb, 2015 | Pubmed ID: 25498564
The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep.
Brain, behavior, and immunity Jul, 2015 | Pubmed ID: 25532785
Zinc-containing yeast extract promotes nonrapid eye movement sleep in mice.
Molecular nutrition & food research Oct, 2015 | Pubmed ID: 26105624
PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia.
Nature communications , 2015 | Pubmed ID: 26159556
Japanese sake yeast supplementation improves the quality of sleep: a double-blind randomised controlled clinical trial.
Journal of sleep research Sep, 2015 | Pubmed ID: 26354605
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