Cardiovascular Division
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Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field.
Circulation research Jan, 2017 | Pubmed ID: 28104767
Extracellular Vesicles As Mediators of Cardiovascular Calcification.
Frontiers in cardiovascular medicine , 2017 | Pubmed ID: 29322046
Extracellular vesicles in cardiovascular homeostasis and disease.
Current opinion in cardiology May, 2018 | Pubmed ID: 29465447
Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.
Circulation Jul, 2018 | Pubmed ID: 29588317
F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed Tomography Images.
Circulation. Cardiovascular imaging Jan, 2019 | Pubmed ID: 30642216
After 50 Years of Heart Transplants: What Does the Next 50 Years Hold for Cardiovascular Medicine? A Perspective From the International Society for Applied Cardiovascular Biology.
Frontiers in cardiovascular medicine , 2019 | Pubmed ID: 30838213
Toxicity assessment of wearable wound sensor constituents on keratinocytes.
Toxicology in vitro : an international journal published in association with BIBRA Aug, 2019 | Pubmed ID: 30928693
Elastin-Dependent Aortic Heart Valve Leaflet Curvature Changes During Cyclic Flexure.
Bioengineering (Basel, Switzerland) May, 2019 | Pubmed ID: 31067726
Oxidative DNA Damage Modulates DNA Methylation Pattern in Human Breast Cancer 1 (BRCA1) Gene via the Crosstalk between DNA Polymerase β and a DNA Methyltransferase.
Cells 01, 2020 | Pubmed ID: 31963223
A Method to Quantify Tensile Biaxial Properties of Mouse Aortic Valve Leaflets.
Journal of biomechanical engineering Oct, 2020 | Pubmed ID: 32291440
Oscillatory fluid-induced mechanobiology in heart valves with parallels to the vasculature.
Vascular biology (Bristol, England) , 2020 | Pubmed ID: 32923975
Integrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits.
Cells Sep, 2020 | Pubmed ID: 32987857
ApoC-III is a novel inducer of calcification in human aortic valves.
The Journal of biological chemistry , 2021 | Pubmed ID: 33334888
Synthetic photoplethysmography (PPG) of the radial artery through parallelized Monte Carlo and its correlation to body mass index (BMI).
Scientific reports Jan, 2021 | Pubmed ID: 33510428
Nanoanalytical analysis of bisphosphonate-driven alterations of microcalcifications using a 3D hydrogel system and in vivo mouse model.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2021 | Pubmed ID: 33795519
Dissecting Calcific Aortic Valve Disease-The Role, Etiology, and Drivers of Valvular Fibrosis.
Frontiers in cardiovascular medicine , 2021 | Pubmed ID: 34041283
Elastogenesis Correlates With Pigment Production in Murine Aortic Valve Leaflets.
Frontiers in cardiovascular medicine , 2021 | Pubmed ID: 34239903
A surface-based calibration approach to enable dynamic and accurate quantification of colorimetric assay systems.
Analytical methods : advancing methods and applications Sep, 2021 | Pubmed ID: 34473147
Pigmentation Affects Elastic Fiber Patterning and Biomechanical Behavior of the Murine Aortic Valve.
Frontiers in cardiovascular medicine , 2021 | Pubmed ID: 34957247
The Developmental Origin of Calcific Aortic Stenosis.
The New England journal of medicine Apr, 2022 | Pubmed ID: 35388675
S2 Heart Sound Detects Aortic Valve Calcification Independent of Hemodynamic Changes in Mice.
Frontiers in cardiovascular medicine , 2022 | Pubmed ID: 35694672
The Time-Dependent Role of Bisphosphonates on Atherosclerotic Plaque Calcification.
Journal of cardiovascular development and disease May, 2022 | Pubmed ID: 35735797
Valve Endothelial Cell Exposure to High Levels of Flow Oscillations Exacerbates Valve Interstitial Cell Calcification.
Bioengineering (Basel, Switzerland) Aug, 2022 | Pubmed ID: 36004918
Editorial: Extracellular vesicles in cardiovascular inflammation and calcification.
Frontiers in cardiovascular medicine , 2022 | Pubmed ID: 36426218
Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity.
European heart journal Jan, 2023 | Pubmed ID: 36660854
Flap Endonuclease 1 Endonucleolytically Processes RNA to Resolve R-Loops through DNA Base Excision Repair.
Genes Dec, 2022 | Pubmed ID: 36672839
Caitlin O'Rourke*,1,
Georgia Shelton*,1,2,
Joshua D. Hutcheson3,4,
Megan F. Burke2,
Trejeeve Martyn1,
Timothy E. Thayer2,
Hannah R. Shakartzi1,
Mary D. Buswell1,
Robert E. Tainsh1,
Binglan Yu1,4,
Aranya Bagchi1,4,
David K. Rhee2,4,
Connie Wu1,2,4,
Matthias Derwall5,
Emmanuel S. Buys1,4,
Paul B. Yu3,4,
Kenneth D. Bloch1,2,4,
Elena Aikawa3,4,
Donald B. Bloch1,5,6,
Rajeev Malhotra2,4
1Anesthesia Center for Critical Care Research of the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital,
2Cardiovascular Research Center and Cardiology Division of the Department of Medicine, Massachusetts General Hospital,
3Cardiovascular Division, Brigham and Women's Hospital,
4, Harvard Medical School,
5Department of Anesthesiology, Uniklinik RWTH Aachen, RWTH Aachen University,
6Center for Immunology and Inflammatory Diseases and the Division of Rheumatology, Allergy, and Immunology of the Department of Medicine, Massachusetts General Hospital
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