Alessio Fasano

Zonula occludin toxin, a microtubule binding protein.

Zonula occludens toxin (Zot) interferes with the induction of nasal tolerance to gliadin.

New developments in childhood celiac disease.

Ganglioside reactive antibodies in the neuropathy associated with celiac disease.

Structural and functional alterations of the gastrointestinal tract following radiation-induced injury in the rhesus monkey.

Infectious diarrhea in children: Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition.

Host-dependent zonulin secretion causes the impairment of the small intestine barrier function after bacterial exposure.

Effect of the biologically active fragment of zonula occludens toxin, delta G, on the intestinal paracellular transport and oral absorption of mannitol.

Zonula occludens toxin increases the permeability of molecular weight markers and chemotherapeutic agents across the bovine brain microvessel endothelial cells.

Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study.

Zonula occludens toxin acts as an adjuvant through different mucosal routes and induces protective immune responses.

Bioterrorism and biological warfare: not only a respiratory affair.

Celiac disease--how to handle a clinical chameleon.

Intestinal epithelial tight junctions as targets for enteric bacteria-derived toxins.

The effect of delta G on the transport and oral absorption of macromolecules.

Intestinal infections and environmental enteropathy: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition.

Celiac disease as a cause of growth retardation in childhood.

The impact of DeltaG on the oral bioavailability of low bioavailable therapeutic agents.

Relationship of HLA-DQ8 and severity of celiac disease: comparison of New York and Parisian cohorts.

Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.

Dual sugar gut-permeability testing on blood drop in animal models.

Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats.

Permeability, zonulin production, and enteropathy in dermatitis herpetiformis.

Clinical presentation of celiac disease in the pediatric population.

Seeing the light with celiac.

Coeliac disease in children.

Secreted autotransporter toxin produced by a diffusely adhering Escherichia coli strain causes intestinal damage in animal model assays.

Current concepts in the evaluation, diagnosis and management of acute infectious diarrhea.

Mechanisms of disease: the role of intestinal barrier function in the pathogenesis of gastrointestinal autoimmune diseases.

Enhancement of brain distribution of anticancer agents using DeltaG, the 12 kDa active fragment of ZOT.

VSL#3 probiotic preparation has the capacity to hydrolyze gliadin polypeptides responsible for Celiac Sprue.

Celiac disease: is the atypical really typical? Summary of the recent National Institutes of Health Consensus Conference and latest advances.

Gliadin stimulation of murine macrophage inflammatory gene expression and intestinal permeability are MyD88-dependent: role of the innate immune response in Celiac disease.

Tight junction modulation and its relationship to drug delivery.

Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines.

Celiac disease in the pediatric population.

Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives.

Zonula occludens toxin synthetic peptide derivative AT1002 enhances in vitro and in vivo intestinal absorption of low molecular weight heparin.

Latest developments in the pathogenesis and treatment of celiac disease.

Systemic autoimmune disorders in celiac disease.

A prospective, double-blind, placebo-controlled trial to establish a safe gluten threshold for patients with celiac disease.

Detection of Celiac disease in primary care: a multicenter case-finding study in North America.

Screening for celiac disease in family members: is follow-up testing necessary?

Mechanisms of disease: protease functions in intestinal mucosal pathobiology.

Effect of the six-mer synthetic peptide (AT1002) fragment of zonula occludens toxin on the intestinal absorption of cyclosporin A.

Enhanced nasal absorption of hydrophilic markers after dosing with AT1002, a tight junction modulator.

Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3.

Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: a novel paradigm for receptor cooperativity.

Is this really celiac disease? Pitfalls in diagnosis.

Cutting edge: IL-1 controls the IL-23 response induced by gliadin, the etiologic agent in celiac disease.

Physiological, pathological, and therapeutic implications of zonulin-mediated intestinal barrier modulation: living life on the edge of the wall.

Celiac disease.

Isolation, identification, and characterization of small bioactive peptides from Lactobacillus GG conditional media that exert both anti-Gram-negative and Gram-positive bactericidal activity.

Prevalence of celiac disease and gluten sensitivity in the United States clinical antipsychotic trials of intervention effectiveness study population.

Tight junctions, intestinal permeability, and autoimmunity: celiac disease and type 1 diabetes paradigms.

Pediatric celiac disease.

Surprises from celiac disease.

Should we screen for coeliac disease? Yes.

Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2.

Differential mucosal IL-17 expression in two gliadin-induced disorders: gluten sensitivity and the autoimmune enteropathy celiac disease.

Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine.

Monocytes differentiated with IL-15 support Th17 and Th1 responses to wheat gliadin: implications for celiac disease.

Commentary on "anti-pituitary antibodies in children with newly diagnosed celiac disease: a novel finding contributing to linear growth".

Celiac disease diagnosis: simple rules are better than complicated algorithms.

The active Zot domain (aa 288-293) increases ZO-1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO-1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation.

Natural history of celiac disease autoimmunity in a USA cohort followed since 1974.

Identification of a novel immunomodulatory gliadin peptide that causes interleukin-8 release in a chemokine receptor CXCR3-dependent manner only in patients with coeliac disease.

Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer.

Enteric pathogens and gut function: Role of cytokines and STATs.

Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity.

Engineering of a multicellular organotypic model of the human intestinal mucosa.

Increased bacterial translocation in gluten-sensitive mice is independent of small intestinal paracellular permeability defect.

Neurologic and psychiatric manifestations of celiac disease and gluten sensitivity.

The expression of caspases is enhanced in peripheral blood mononuclear cells of autism spectrum disorder patients.

Early feeding practices and their impact on development of celiac disease.

Matriptase protects against experimental colitis and promotes intestinal barrier recovery.

Leaky gut and autoimmune diseases.

Spectrum of gluten-related disorders: consensus on new nomenclature and classification.

The Oslo definitions for coeliac disease and related terms.

Proof of concept of microbiome-metabolome analysis and delayed gluten exposure on celiac disease autoimmunity in genetically at-risk infants.

The cannabinoid receptor type 2 Q63R variant increases the risk of celiac disease: implication for a novel molecular biomarker and future therapeutic intervention.

Increased prevalence of transglutaminase 6 antibodies in sera from schizophrenia patients.

Timing of introduction of gluten and celiac disease risk.

Association analysis of the extended MHC region in celiac disease implicates multiple independent susceptibility loci.

Prevalence and natural history of potential celiac disease in at-family-risk infants prospectively investigated from birth.

Zonulin, regulation of tight junctions, and autoimmune diseases.

A gluten-free diet in people with schizophrenia and anti-tissue transglutaminase or anti-gliadin antibodies.

Intestinal permeability and its regulation by zonulin: diagnostic and therapeutic implications.

Major signaling pathways in intestinal stem cells.

Presentation of celiac disease.

Novel therapeutic/integrative approaches for celiac disease and dermatitis herpetiformis.

Gastrointestinal conditions in children with autism spectrum disorder: developing a research agenda.

Chromosomal and plasmid-encoded factors of Shigella flexneri induce secretogenic activity ex vivo.

Might gluten traces in wheat substitutes pose a risk in patients with celiac disease? A population-based probabilistic approach to risk estimation.

Clinical practice. Celiac disease.

Microbiota and gut-liver axis: their influences on obesity and obesity-related liver disease.

Helicobacter pylori-induced disruption of monolayer permeability and proinflammatory cytokine secretion in polarized human gastric epithelial cells.

World Gastroenterology Organisation global guidelines on celiac disease.

Novel advances in dermatitis herpetiformis.

In vitro Intestinal Mucosal Epithelial Responses to Wild-Type Salmonella Typhi and Attenuated Typhoid Vaccines.

Progress and pitfalls in Shigella vaccine research.

Trace gluten contamination may play a role in mucosal and clinical recovery in a subgroup of diet-adherent non-responsive celiac disease patients.

Markers of Inflammation and Lineage on Exfoliated Colonic Cells In Pediatric Inflammatory Bowel Disease.

Zonulin as prehaptoglobin2 regulates lung permeability and activates the complement system.

Cannabinoid receptor type 2, but not type 1, is up-regulated in peripheral blood mononuclear cells of children affected by autistic disorders.

Gut microbiota, tight junction protein expression, intestinal resistance, bacterial translocation and mortality following cholestasis depend on the genetic background of the host.

Antibodies against food antigens in patients with autistic spectrum disorders.

Non-Celiac Gluten sensitivity: the new frontier of gluten related disorders.

Effect of wild-type Shigella species and attenuated Shigella vaccine candidates on small intestinal barrier function, antigen trafficking, and cytokine release.

Prediction of celiac disease at endoscopy.

Analytical and clinical comparison of two fully automated immunoassay systems for the diagnosis of celiac disease.

Celiac disease: past, present, and future challenges: dedicated to the memory of our friend and colleague, Prof David Branski (1944-2013).

The new epidemiology of celiac disease.

Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus.

Coeliac disease. The debate on coeliac disease screening--are we there yet?

Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.

Introduction of gluten, HLA status, and the risk of celiac disease in children.

Genetics and celiac disease: the importance of screening.

Gluten sensitivity and relationship to psychiatric symptoms in people with schizophrenia.

Duodenal lymphocytosis with no or minimal enteropathy: much ado about nothing?

Nonceliac gluten sensitivity.

Mammalian gastrointestinal tract parameters modulating the integrity, surface properties, and absorption of food-relevant nanomaterials.

Effect of gliadin on permeability of intestinal biopsy explants from celiac disease patients and patients with non-celiac gluten sensitivity.

Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts' Criteria.

Remission of Refractory Celiac Disease With Infliximab in a Pediatric Patient.

Gluten Introduction, Breastfeeding, and Celiac Disease: Back to the Drawing Board.

Extraintestinal manifestations of coeliac disease.

The Role of Gluten in Celiac Disease and Type 1 Diabetes.

Gliadin Induces Neutrophil Migration via Engagement of the Formyl Peptide Receptor, FPR1.

Celiac Disease Genomic, Environmental, Microbiome, and Metabolomic (CDGEMM) Study Design: Approach to the Future of Personalized Prevention of Celiac Disease.

Celiac Disease Histopathology Recapitulates Hedgehog Downregulation, Consistent with Wound Healing Processes Activation.

Gut microbiome and necrotising enterocolitis: time for intervention?

The microbiome as a possible target to prevent celiac disease.

NASPGHAN Clinical Report on the Diagnosis and Treatment of Gluten-related Disorders.

Free and complexed-secretory immunoglobulin A triggers distinct intestinal epithelial responses.

CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 14-2016. A 37-Year-Old Woman with Adult-Onset Psychosis.

Mechanisms Involved in the Development of the Chronic Gastrointestinal Syndrome in Nonhuman Primates after Total-Body Irradiation with Bone Marrow Shielding.

Emergency Department Utilization Report to Decrease Visits by Pediatric Gastroenterology Patients.

[Design of a genomic, environmental, microbial and metabolomic study on celiac disease: an approach to the future of personalized prevention of celiac disease].

Celiac disease diagnosis still significantly delayed - Doctor's but not patients' delay responsive for the increased total delay in women.