Mucosal Immunology and Biology Research Center
Alessio Fasano has not added Biography.
If you are Alessio Fasano and would like to personalize this page please email our Author Liaison for assistance.
Zonula occludin toxin, a microtubule binding protein.
World journal of gastroenterology Jun, 2000 | Pubmed ID: 11819591
Zonula occludens toxin (Zot) interferes with the induction of nasal tolerance to gliadin.
Immunology letters May, 2002 | Pubmed ID: 11947928
New developments in childhood celiac disease.
Current gastroenterology reports Jun, 2002 | Pubmed ID: 12010625
Ganglioside reactive antibodies in the neuropathy associated with celiac disease.
Journal of neuroimmunology Jun, 2002 | Pubmed ID: 12044986
Structural and functional alterations of the gastrointestinal tract following radiation-induced injury in the rhesus monkey.
Digestive diseases and sciences Jul, 2002 | Pubmed ID: 12141804
Infectious diarrhea in children: Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition.
Journal of pediatric gastroenterology and nutrition , 2002 | Pubmed ID: 12192183
Host-dependent zonulin secretion causes the impairment of the small intestine barrier function after bacterial exposure.
Gastroenterology Nov, 2002 | Pubmed ID: 12404235
Effect of the biologically active fragment of zonula occludens toxin, delta G, on the intestinal paracellular transport and oral absorption of mannitol.
International journal of pharmaceutics Jan, 2003 | Pubmed ID: 12527181
Zonula occludens toxin increases the permeability of molecular weight markers and chemotherapeutic agents across the bovine brain microvessel endothelial cells.
Journal of pharmaceutical sciences Feb, 2003 | Pubmed ID: 12532391
Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study.
Archives of internal medicine Feb, 2003 | Pubmed ID: 12578508
Zonula occludens toxin acts as an adjuvant through different mucosal routes and induces protective immune responses.
Infection and immunity Apr, 2003 | Pubmed ID: 12654806
Bioterrorism and biological warfare: not only a respiratory affair.
Journal of pediatric gastroenterology and nutrition Mar, 2003 | Pubmed ID: 12669708
Celiac disease--how to handle a clinical chameleon.
The New England journal of medicine Jun, 2003 | Pubmed ID: 12815143
Intestinal epithelial tight junctions as targets for enteric bacteria-derived toxins.
Advanced drug delivery reviews Apr, 2004 | Pubmed ID: 15063590
The effect of delta G on the transport and oral absorption of macromolecules.
Journal of pharmaceutical sciences May, 2004 | Pubmed ID: 15067707
Intestinal infections and environmental enteropathy: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition.
Journal of pediatric gastroenterology and nutrition Jun, 2004 | Pubmed ID: 15184767
Celiac disease as a cause of growth retardation in childhood.
Current opinion in pediatrics Aug, 2004 | Pubmed ID: 15273508
The impact of DeltaG on the oral bioavailability of low bioavailable therapeutic agents.
The Journal of pharmacology and experimental therapeutics Jan, 2005 | Pubmed ID: 15448170
Relationship of HLA-DQ8 and severity of celiac disease: comparison of New York and Parisian cohorts.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Oct, 2004 | Pubmed ID: 15476152
Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.
Journal of pediatric gastroenterology and nutrition Jan, 2005 | Pubmed ID: 15625418
Dual sugar gut-permeability testing on blood drop in animal models.
Clinica chimica acta; international journal of clinical chemistry Feb, 2005 | Pubmed ID: 15653114
Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2005 | Pubmed ID: 15710870
Permeability, zonulin production, and enteropathy in dermatitis herpetiformis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Apr, 2005 | Pubmed ID: 15822038
Clinical presentation of celiac disease in the pediatric population.
Gastroenterology Apr, 2005 | Pubmed ID: 15825129
Seeing the light with celiac.
Clinical immunology (Orlando, Fla.) Jun, 2005 | Pubmed ID: 15893690
Coeliac disease in children.
Best practice & research. Clinical gastroenterology Jun, 2005 | Pubmed ID: 15925850
Secreted autotransporter toxin produced by a diffusely adhering Escherichia coli strain causes intestinal damage in animal model assays.
FEMS microbiology letters Sep, 2005 | Pubmed ID: 16098687
Current concepts in the evaluation, diagnosis and management of acute infectious diarrhea.
Current opinion in pharmacology Dec, 2005 | Pubmed ID: 16207535
Mechanisms of disease: the role of intestinal barrier function in the pathogenesis of gastrointestinal autoimmune diseases.
Nature clinical practice. Gastroenterology & hepatology Sep, 2005 | Pubmed ID: 16265432
Enhancement of brain distribution of anticancer agents using DeltaG, the 12 kDa active fragment of ZOT.
International journal of pharmaceutics Dec, 2005 | Pubmed ID: 16274945
VSL#3 probiotic preparation has the capacity to hydrolyze gliadin polypeptides responsible for Celiac Sprue.
Biochimica et biophysica acta Jan, 2006 | Pubmed ID: 16311022
Celiac disease: is the atypical really typical? Summary of the recent National Institutes of Health Consensus Conference and latest advances.
Current gastroenterology reports Dec, 2005 | Pubmed ID: 16313875
Gliadin stimulation of murine macrophage inflammatory gene expression and intestinal permeability are MyD88-dependent: role of the innate immune response in Celiac disease.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2006 | Pubmed ID: 16456012
Tight junction modulation and its relationship to drug delivery.
Advanced drug delivery reviews Apr, 2006 | Pubmed ID: 16517003
Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines.
Scandinavian journal of gastroenterology Apr, 2006 | Pubmed ID: 16635908
Celiac disease in the pediatric population.
Pediatric annals Apr, 2006 | Pubmed ID: 16637556
Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives.
Diabetes May, 2006 | Pubmed ID: 16644703
Zonula occludens toxin synthetic peptide derivative AT1002 enhances in vitro and in vivo intestinal absorption of low molecular weight heparin.
Journal of drug targeting Jun, 2006 | Pubmed ID: 16882552
Latest developments in the pathogenesis and treatment of celiac disease.
The Journal of pediatrics Sep, 2006 | Pubmed ID: 16939736
Systemic autoimmune disorders in celiac disease.
Current opinion in gastroenterology Nov, 2006 | Pubmed ID: 17053448
A prospective, double-blind, placebo-controlled trial to establish a safe gluten threshold for patients with celiac disease.
The American journal of clinical nutrition Jan, 2007 | Pubmed ID: 17209192
Detection of Celiac disease in primary care: a multicenter case-finding study in North America.
The American journal of gastroenterology Jul, 2007 | Pubmed ID: 17355413
Screening for celiac disease in family members: is follow-up testing necessary?
Digestive diseases and sciences Apr, 2007 | Pubmed ID: 17380406
Mechanisms of disease: protease functions in intestinal mucosal pathobiology.
Nature clinical practice. Gastroenterology & hepatology Jul, 2007 | Pubmed ID: 17607295
Effect of the six-mer synthetic peptide (AT1002) fragment of zonula occludens toxin on the intestinal absorption of cyclosporin A.
International journal of pharmaceutics Mar, 2008 | Pubmed ID: 17954018
Enhanced nasal absorption of hydrophilic markers after dosing with AT1002, a tight junction modulator.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V May, 2008 | Pubmed ID: 18039562
Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3.
Gastroenterology Jul, 2008 | Pubmed ID: 18485912
Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: a novel paradigm for receptor cooperativity.
The Journal of biological chemistry Sep, 2008 | Pubmed ID: 18622013
Is this really celiac disease? Pitfalls in diagnosis.
Current gastroenterology reports Oct, 2008 | Pubmed ID: 18799121
Cutting edge: IL-1 controls the IL-23 response induced by gliadin, the etiologic agent in celiac disease.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2008 | Pubmed ID: 18802048
Physiological, pathological, and therapeutic implications of zonulin-mediated intestinal barrier modulation: living life on the edge of the wall.
The American journal of pathology Nov, 2008 | Pubmed ID: 18832585
Celiac disease.
Current opinion in gastroenterology Nov, 2008 | Pubmed ID: 19122516
Isolation, identification, and characterization of small bioactive peptides from Lactobacillus GG conditional media that exert both anti-Gram-negative and Gram-positive bactericidal activity.
Journal of pediatric gastroenterology and nutrition Jul, 2009 | Pubmed ID: 19465870
Prevalence of celiac disease and gluten sensitivity in the United States clinical antipsychotic trials of intervention effectiveness study population.
Schizophrenia bulletin Jan, 2011 | Pubmed ID: 19494248
Tight junctions, intestinal permeability, and autoimmunity: celiac disease and type 1 diabetes paradigms.
Annals of the New York Academy of Sciences May, 2009 | Pubmed ID: 19538307
Pediatric celiac disease.
Current opinion in pediatrics Oct, 2009 | Pubmed ID: 19606042
Surprises from celiac disease.
Scientific American Aug, 2009 | Pubmed ID: 19634568
Should we screen for coeliac disease? Yes.
BMJ (Clinical research ed.) , 2009 | Pubmed ID: 19762413
Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2009 | Pubmed ID: 19805376
Differential mucosal IL-17 expression in two gliadin-induced disorders: gluten sensitivity and the autoimmune enteropathy celiac disease.
International archives of allergy and immunology , 2010 | Pubmed ID: 19940509
Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2010 | Pubmed ID: 20142489
Monocytes differentiated with IL-15 support Th17 and Th1 responses to wheat gliadin: implications for celiac disease.
Clinical immunology (Orlando, Fla.) Jun, 2010 | Pubmed ID: 20153259
Commentary on "anti-pituitary antibodies in children with newly diagnosed celiac disease: a novel finding contributing to linear growth".
The American journal of gastroenterology Mar, 2010 | Pubmed ID: 20203647
Celiac disease diagnosis: simple rules are better than complicated algorithms.
The American journal of medicine Aug, 2010 | Pubmed ID: 20670718
The active Zot domain (aa 288-293) increases ZO-1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO-1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jan, 2011 | Pubmed ID: 20852064
Natural history of celiac disease autoimmunity in a USA cohort followed since 1974.
Annals of medicine Oct, 2010 | Pubmed ID: 20868314
Identification of a novel immunomodulatory gliadin peptide that causes interleukin-8 release in a chemokine receptor CXCR3-dependent manner only in patients with coeliac disease.
Immunology Mar, 2011 | Pubmed ID: 21091908
Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer.
Physiological reviews Jan, 2011 | Pubmed ID: 21248165
Enteric pathogens and gut function: Role of cytokines and STATs.
Gut microbes 9, 2010 | Pubmed ID: 21327040
Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity.
BMC medicine , 2011 | Pubmed ID: 21392369
Engineering of a multicellular organotypic model of the human intestinal mucosa.
Gastroenterology Aug, 2011 | Pubmed ID: 21723866
Increased bacterial translocation in gluten-sensitive mice is independent of small intestinal paracellular permeability defect.
Digestive diseases and sciences Jan, 2012 | Pubmed ID: 21822909
Neurologic and psychiatric manifestations of celiac disease and gluten sensitivity.
The Psychiatric quarterly Mar, 2012 | Pubmed ID: 21877216
The expression of caspases is enhanced in peripheral blood mononuclear cells of autism spectrum disorder patients.
Journal of autism and developmental disorders Jul, 2012 | Pubmed ID: 21969075
Early feeding practices and their impact on development of celiac disease.
Nestlé Nutrition workshop series. Paediatric programme , 2011 | Pubmed ID: 22044901
Matriptase protects against experimental colitis and promotes intestinal barrier recovery.
Inflammatory bowel diseases Jul, 2012 | Pubmed ID: 22081509
Leaky gut and autoimmune diseases.
Clinical reviews in allergy & immunology Feb, 2012 | Pubmed ID: 22109896
Spectrum of gluten-related disorders: consensus on new nomenclature and classification.
BMC medicine , 2012 | Pubmed ID: 22313950
The Oslo definitions for coeliac disease and related terms.
Gut Jan, 2013 | Pubmed ID: 22345659
Proof of concept of microbiome-metabolome analysis and delayed gluten exposure on celiac disease autoimmunity in genetically at-risk infants.
PloS one , 2012 | Pubmed ID: 22432018
The cannabinoid receptor type 2 Q63R variant increases the risk of celiac disease: implication for a novel molecular biomarker and future therapeutic intervention.
Pharmacological research Jul, 2012 | Pubmed ID: 22465144
Increased prevalence of transglutaminase 6 antibodies in sera from schizophrenia patients.
Schizophrenia bulletin Jul, 2013 | Pubmed ID: 22516148
Timing of introduction of gluten and celiac disease risk.
Annals of nutrition & metabolism , 2012 | Pubmed ID: 22555186
Association analysis of the extended MHC region in celiac disease implicates multiple independent susceptibility loci.
PloS one , 2012 | Pubmed ID: 22615847
Prevalence and natural history of potential celiac disease in at-family-risk infants prospectively investigated from birth.
The Journal of pediatrics Nov, 2012 | Pubmed ID: 22704250
Zonulin, regulation of tight junctions, and autoimmune diseases.
Annals of the New York Academy of Sciences Jul, 2012 | Pubmed ID: 22731712
A gluten-free diet in people with schizophrenia and anti-tissue transglutaminase or anti-gliadin antibodies.
Schizophrenia research Sep, 2012 | Pubmed ID: 22771303
Intestinal permeability and its regulation by zonulin: diagnostic and therapeutic implications.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Oct, 2012 | Pubmed ID: 22902773
Major signaling pathways in intestinal stem cells.
Biochimica et biophysica acta Feb, 2013 | Pubmed ID: 22922290
Presentation of celiac disease.
Gastrointestinal endoscopy clinics of North America Oct, 2012 | Pubmed ID: 23083982
Novel therapeutic/integrative approaches for celiac disease and dermatitis herpetiformis.
Clinical & developmental immunology , 2012 | Pubmed ID: 23093980
Gastrointestinal conditions in children with autism spectrum disorder: developing a research agenda.
Pediatrics Nov, 2012 | Pubmed ID: 23118247
Chromosomal and plasmid-encoded factors of Shigella flexneri induce secretogenic activity ex vivo.
PloS one , 2012 | Pubmed ID: 23166804
Might gluten traces in wheat substitutes pose a risk in patients with celiac disease? A population-based probabilistic approach to risk estimation.
The American journal of clinical nutrition Jan, 2013 | Pubmed ID: 23193005
Clinical practice. Celiac disease.
The New England journal of medicine Dec, 2012 | Pubmed ID: 23252527
Microbiota and gut-liver axis: their influences on obesity and obesity-related liver disease.
Journal of pediatric gastroenterology and nutrition May, 2013 | Pubmed ID: 23287807
Helicobacter pylori-induced disruption of monolayer permeability and proinflammatory cytokine secretion in polarized human gastric epithelial cells.
Infection and immunity Mar, 2013 | Pubmed ID: 23297384
World Gastroenterology Organisation global guidelines on celiac disease.
Journal of clinical gastroenterology Feb, 2013 | Pubmed ID: 23314668
Novel advances in dermatitis herpetiformis.
Clinical & developmental immunology , 2012 | Pubmed ID: 23316253
In vitro Intestinal Mucosal Epithelial Responses to Wild-Type Salmonella Typhi and Attenuated Typhoid Vaccines.
Frontiers in immunology , 2013 | Pubmed ID: 23408152
Progress and pitfalls in Shigella vaccine research.
Nature reviews. Gastroenterology & hepatology Apr, 2013 | Pubmed ID: 23419287
Trace gluten contamination may play a role in mucosal and clinical recovery in a subgroup of diet-adherent non-responsive celiac disease patients.
BMC gastroenterology , 2013 | Pubmed ID: 23448408
Markers of Inflammation and Lineage on Exfoliated Colonic Cells In Pediatric Inflammatory Bowel Disease.
Journal of gastrointestinal & digestive system Dec, 2011 | Pubmed ID: 23519721
Zonulin as prehaptoglobin2 regulates lung permeability and activates the complement system.
American journal of physiology. Lung cellular and molecular physiology Jun, 2013 | Pubmed ID: 23564505
Cannabinoid receptor type 2, but not type 1, is up-regulated in peripheral blood mononuclear cells of children affected by autistic disorders.
Journal of autism and developmental disorders Nov, 2013 | Pubmed ID: 23585028
Gut microbiota, tight junction protein expression, intestinal resistance, bacterial translocation and mortality following cholestasis depend on the genetic background of the host.
Gut microbes Jul-Aug, 2013 | Pubmed ID: 23652772
Antibodies against food antigens in patients with autistic spectrum disorders.
BioMed research international , 2013 | Pubmed ID: 23984403
Non-Celiac Gluten sensitivity: the new frontier of gluten related disorders.
Nutrients Oct, 2013 | Pubmed ID: 24077239
Effect of wild-type Shigella species and attenuated Shigella vaccine candidates on small intestinal barrier function, antigen trafficking, and cytokine release.
PloS one , 2014 | Pubmed ID: 24416363
Prediction of celiac disease at endoscopy.
Endoscopy Feb, 2014 | Pubmed ID: 24477366
Analytical and clinical comparison of two fully automated immunoassay systems for the diagnosis of celiac disease.
Journal of immunology research , 2014 | Pubmed ID: 24741592
Celiac disease: past, present, and future challenges: dedicated to the memory of our friend and colleague, Prof David Branski (1944-2013).
Journal of pediatric gastroenterology and nutrition Jul, 2014 | Pubmed ID: 24840514
The new epidemiology of celiac disease.
Journal of pediatric gastroenterology and nutrition Jul, 2014 | Pubmed ID: 24979197
Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus.
PloS one , 2014 | Pubmed ID: 24999842
Coeliac disease. The debate on coeliac disease screening--are we there yet?
Nature reviews. Gastroenterology & hepatology Aug, 2014 | Pubmed ID: 25001972
Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.
Immunity Aug, 2014 | Pubmed ID: 25065623
Introduction of gluten, HLA status, and the risk of celiac disease in children.
The New England journal of medicine Oct, 2014 | Pubmed ID: 25271602
Genetics and celiac disease: the importance of screening.
Expert review of gastroenterology & hepatology Feb, 2015 | Pubmed ID: 25294637
Gluten sensitivity and relationship to psychiatric symptoms in people with schizophrenia.
Schizophrenia research Nov, 2014 | Pubmed ID: 25311778
Duodenal lymphocytosis with no or minimal enteropathy: much ado about nothing?
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Jan, 2015 | Pubmed ID: 25560597
Nonceliac gluten sensitivity.
Gastroenterology May, 2015 | Pubmed ID: 25583468
Mammalian gastrointestinal tract parameters modulating the integrity, surface properties, and absorption of food-relevant nanomaterials.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology Sep-Oct, 2015 | Pubmed ID: 25641962
Effect of gliadin on permeability of intestinal biopsy explants from celiac disease patients and patients with non-celiac gluten sensitivity.
Nutrients Mar, 2015 | Pubmed ID: 25734566
Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts' Criteria.
Nutrients Jun, 2015 | Pubmed ID: 26096570
Remission of Refractory Celiac Disease With Infliximab in a Pediatric Patient.
ACG case reports journal Jan, 2015 | Pubmed ID: 26157934
Gluten Introduction, Breastfeeding, and Celiac Disease: Back to the Drawing Board.
The American journal of gastroenterology Jan, 2016 | Pubmed ID: 26259710
Extraintestinal manifestations of coeliac disease.
Nature reviews. Gastroenterology & hepatology Oct, 2015 | Pubmed ID: 26260366
The Role of Gluten in Celiac Disease and Type 1 Diabetes.
Nutrients Sep, 2015 | Pubmed ID: 26343710
Gliadin Induces Neutrophil Migration via Engagement of the Formyl Peptide Receptor, FPR1.
PloS one , 2015 | Pubmed ID: 26378785
Celiac Disease Genomic, Environmental, Microbiome, and Metabolomic (CDGEMM) Study Design: Approach to the Future of Personalized Prevention of Celiac Disease.
Nutrients Nov, 2015 | Pubmed ID: 26569299
Celiac Disease Histopathology Recapitulates Hedgehog Downregulation, Consistent with Wound Healing Processes Activation.
PloS one , 2015 | Pubmed ID: 26649570
Gut microbiome and necrotising enterocolitis: time for intervention?
Lancet (London, England) May, 2016 | Pubmed ID: 26969092
The microbiome as a possible target to prevent celiac disease.
Expert review of gastroenterology & hepatology May, 2016 | Pubmed ID: 26999627
NASPGHAN Clinical Report on the Diagnosis and Treatment of Gluten-related Disorders.
Journal of pediatric gastroenterology and nutrition Jul, 2016 | Pubmed ID: 27035374
Free and complexed-secretory immunoglobulin A triggers distinct intestinal epithelial responses.
Clinical and experimental immunology Apr, 2016 | Pubmed ID: 27084834
CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 14-2016. A 37-Year-Old Woman with Adult-Onset Psychosis.
The New England journal of medicine May, 2016 | Pubmed ID: 27168437
Mechanisms Involved in the Development of the Chronic Gastrointestinal Syndrome in Nonhuman Primates after Total-Body Irradiation with Bone Marrow Shielding.
Radiation research Jun, 2016 | Pubmed ID: 27223826
Emergency Department Utilization Report to Decrease Visits by Pediatric Gastroenterology Patients.
Pediatrics Jul, 2016 | Pubmed ID: 27287727
[Design of a genomic, environmental, microbial and metabolomic study on celiac disease: an approach to the future of personalized prevention of celiac disease].
Recenti progressi in medicina Jun, 2016 | Pubmed ID: 27362724
Celiac disease diagnosis still significantly delayed - Doctor's but not patients' delay responsive for the increased total delay in women.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver Jun, 2016 | Pubmed ID: 27401607
JoVE 소개
Copyright © 2024 MyJoVE Corporation. 판권 소유