Sunny Akogwu Abbah
Centre for Research in Medical Devices (CÚRAM)
National University of Ireland Galway
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In vivo bioactivity of rhBMP-2 delivered with novel polyelectrolyte complexation shells assembled on an alginate microbead core template.
Journal of controlled release : official journal of the Controlled Release Society Sep, 2012 | Pubmed ID: 22846985
Enhanced control of in vivo bone formation with surface functionalized alginate microbeads incorporating heparin and human bone morphogenetic protein-2.
Tissue engineering. Part A Feb, 2013 | Pubmed ID: 22894570
Minimizing the severity of rhBMP-2-induced inflammation and heterotopic ossification with a polyelectrolyte carrier incorporating heparin on microbead templates.
Spine Aug, 2013 | Pubmed ID: 23380826
Sequestration of rhBMP-2 into self-assembled polyelectrolyte complexes promotes anatomic localization of new bone in a porcine model of spinal reconstructive surgery.
Tissue engineering. Part A Jun, 2014 | Pubmed ID: 24354664
Preferential tendon stem cell response to growth factor supplementation.
Journal of tissue engineering and regenerative medicine Jan, 2014 | Pubmed ID: 24474722
Assessment of stem cell carriers for tendon tissue engineering in pre-clinical models.
Stem cell research & therapy , 2014 | Pubmed ID: 25157898
Biomimetic approaches in bone tissue engineering: Integrating biological and physicomechanical strategies.
Advanced drug delivery reviews Apr, 2015 | Pubmed ID: 25236302
Novel Protamine-Based Polyelectrolyte Carrier Enhances Low-Dose rhBMP-2 in Posterolateral Spinal Fusion.
Spine May, 2015 | Pubmed ID: 25705961
Polyelectrolyte Complex Carrier Enhances Therapeutic Efficiency and Safety Profile of Bone Morphogenetic Protein-2 in Porcine Lumbar Interbody Fusion Model.
Spine Jul, 2015 | Pubmed ID: 25893351
Bone marrow-derived mesenchymal stem cells assembled with low-dose BMP-2 in a three-dimensional hybrid construct enhances posterolateral spinal fusion in syngeneic rats.
The spine journal : official journal of the North American Spine Society Dec, 2015 | Pubmed ID: 26342750
Polyelectrolyte Complex for Heparin Binding Domain Osteogenic Growth Factor Delivery
Raymond Wing Moon Lam1,
Sunny Akogwu Abbah2,
Wang Ming1,
Mathanapriya Naidu1,
Felly Ng1,
Hu Tao1,
James Goh Cho Hong3,4,
Kang Ting5,
Wong Hee Kit1,4
1Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore,
2Centre for Research in Medical Devices (CÚRAM), National University of Ireland Galway,
3Department of Bioengineering, Faculty of Engineering, National University of Singapore,
4Tissue Engineering Program, National University of Singapore,
5Department of Orthopaedic Surgery and the Orthopaedic Hospital Research Center, University of California, Los Angeles
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