The Breast Cancer Now Toby Robins Research Centre,
Division of Breast Cancer,
Division of Molecular Pathology,
The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer
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High-resolution deletion mapping of 15q13.2-q21.1 in transitional cell carcinoma of the bladder.
Cancer research Nov, 2003 | Pubmed ID: 14633686
Prognostic classification of relapsing favorable histology Wilms tumor using cDNA microarray expression profiling and support vector machines.
Genes, chromosomes & cancer Sep, 2004 | Pubmed ID: 15236318
Array CGH using whole genome amplification of fresh-frozen and formalin-fixed, paraffin-embedded tumor DNA.
Genomics Feb, 2006 | Pubmed ID: 16271290
Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization.
Laboratory investigation; a journal of technical methods and pathology Apr, 2006 | Pubmed ID: 16446704
Blastemal expression of type I insulin-like growth factor receptor in Wilms' tumors is driven by increased copy number and correlates with relapse.
Cancer research Dec, 2006 | Pubmed ID: 17145858
Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research Dec, 2006 | Pubmed ID: 17189400
Delineation of a 1Mb breakpoint region at 1p13 in Wilms tumors by fine-tiling oligonucleotide array CGH.
Genes, chromosomes & cancer Jun, 2007 | Pubmed ID: 17370329
Getting it right: designing microarray (and not 'microawry') comparative genomic hybridization studies for cancer research.
Laboratory investigation; a journal of technical methods and pathology Aug, 2007 | Pubmed ID: 17558419
Chromogenic and fluorescent in situ hybridization in breast cancer.
Human pathology Aug, 2007 | Pubmed ID: 17640550
Multifaceted dysregulation of the epidermal growth factor receptor pathway in clear cell sarcoma of the kidney.
Clinical cancer research : an official journal of the American Association for Cancer Research Aug, 2007 | Pubmed ID: 17646270
Resistance to therapy caused by intragenic deletion in BRCA2.
Nature Feb, 2008 | Pubmed ID: 18264088
Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines.
Laboratory investigation; a journal of technical methods and pathology May, 2008 | Pubmed ID: 18332872
ESR1 gene amplification in breast cancer: a common phenomenon?
Nature genetics Jul, 2008 | Pubmed ID: 18583966
Loss of 16q in high grade breast cancer is associated with estrogen receptor status: Evidence for progression in tumors with a luminal phenotype?
Genes, chromosomes & cancer Apr, 2009 | Pubmed ID: 19156836
PPM1D is a potential therapeutic target in ovarian clear cell carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research Apr, 2009 | Pubmed ID: 19293255
Tiling path genomic profiling of grade 3 invasive ductal breast cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research Apr, 2009 | Pubmed ID: 19318498
CD44 is overexpressed in basal-like breast cancers but is not a driver of 11p13 amplification.
Breast cancer research and treatment Feb, 2010 | Pubmed ID: 19350388
Integrated functional, gene expression and genomic analysis for the identification of cancer targets.
PloS one , 2009 | Pubmed ID: 19357772
Mixed micropapillary-ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components.
The Journal of pathology Jul, 2009 | Pubmed ID: 19479727
An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers.
Breast cancer research and treatment Jun, 2010 | Pubmed ID: 19688261
Loss of heterozygosity at 2q37 in sporadic Wilms' tumor: putative role for miR-562.
Clinical cancer research : an official journal of the American Association for Cancer Research Oct, 2009 | Pubmed ID: 19789318
The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type.
The Journal of pathology Jan, 2010 | Pubmed ID: 19877120
Microglandular adenosis or microglandular adenoma? A molecular genetic analysis of a case associated with atypia and invasive carcinoma.
Histopathology Dec, 2009 | Pubmed ID: 19922592
Complex landscapes of somatic rearrangement in human breast cancer genomes.
Nature Dec, 2009 | Pubmed ID: 20033038
Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas.
The Journal of pathology Apr, 2010 | Pubmed ID: 20099298
FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer.
Cancer research Mar, 2010 | Pubmed ID: 20179196
Breast cancer molecular profiling with single sample predictors: a retrospective analysis.
The Lancet. Oncology Apr, 2010 | Pubmed ID: 20181526
Cortactin gene amplification and expression in breast cancer: a chromogenic in situ hybridisation and immunohistochemical study.
Breast cancer research and treatment Dec, 2010 | Pubmed ID: 20213079
Genomic and immunohistochemical analysis of adenosquamous carcinoma of the breast.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Jul, 2010 | Pubmed ID: 20453835
DNA amplifications in breast cancer: genotypic-phenotypic correlations.
Future oncology (London, England) Jun, 2010 | Pubmed ID: 20528234
PPM1D gene amplification and overexpression in breast cancer: a qRT-PCR and chromogenic in situ hybridization study.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Oct, 2010 | Pubmed ID: 20543821
Transcriptomic analysis of tubular carcinomas of the breast reveals similarities and differences with molecular subtype-matched ductal and lobular carcinomas.
The Journal of pathology Sep, 2010 | Pubmed ID: 20593406
BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells.
Cell stem cell Sep, 2010 | Pubmed ID: 20804975
Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type.
The Journal of pathology Nov, 2010 | Pubmed ID: 20815046
Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer.
European journal of cancer (Oxford, England : 1990) Jan, 2011 | Pubmed ID: 20832293
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors.
Science translational medicine Oct, 2010 | Pubmed ID: 20944090
β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Feb, 2011 | Pubmed ID: 21076461
Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers.
Breast cancer research : BCR Jan, 2011 | Pubmed ID: 21255398
Genomic analysis reveals the molecular heterogeneity of ovarian clear cell carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research Mar, 2011 | Pubmed ID: 21411445
Microarray-based class discovery for molecular classification of breast cancer: analysis of interobserver agreement.
Journal of the National Cancer Institute Apr, 2011 | Pubmed ID: 21421860
Genomic profiling of mitochondrion-rich breast carcinoma: chromosomal changes may be relevant for mitochondria accumulation and tumour biology.
Breast cancer research and treatment Feb, 2012 | Pubmed ID: 21509527
Next-generation sequencing applied to molecular diagnostics.
Expert review of molecular diagnostics May, 2011 | Pubmed ID: 21545259
FGFR signaling promotes the growth of triple-negative and basal-like breast cancer cell lines both in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research Aug, 2011 | Pubmed ID: 21712446
Functional characterization of EMSY gene amplification in human cancers.
The Journal of pathology Sep, 2011 | Pubmed ID: 21735447
High-throughput detection of fusion genes in cancer using the Sequenom MassARRAY platform.
Laboratory investigation; a journal of technical methods and pathology Oct, 2011 | Pubmed ID: 21808235
Molecular profiling reveals frequent gain of MYCN and anaplasia-specific loss of 4q and 14q in Wilms tumor.
Genes, chromosomes & cancer Dec, 2011 | Pubmed ID: 21882282
Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma.
Science translational medicine Aug, 2011 | Pubmed ID: 21885404
Non-existence of caveolin-1 gene mutations in human breast cancer.
Breast cancer research and treatment Jan, 2012 | Pubmed ID: 21909981
Functional viability profiles of breast cancer.
Cancer discovery Aug, 2011 | Pubmed ID: 21984977
Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple-negative and basal-like breast cancers.
The Journal of pathology Jan, 2012 | Pubmed ID: 22015727
Immunophenotypic and genomic characterization of papillary carcinomas of the breast.
The Journal of pathology Feb, 2012 | Pubmed ID: 22025283
Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell lines.
BMC medical genomics Oct, 2011 | Pubmed ID: 22032724
Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.
Nature medicine Dec, 2011 | Pubmed ID: 22101766
Genomic and mutational profiling of ductal carcinomas in situ and matched adjacent invasive breast cancers reveals intra-tumour genetic heterogeneity and clonal selection.
The Journal of pathology May, 2012 | Pubmed ID: 22252965
APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer.
The EMBO journal Mar, 2012 | Pubmed ID: 22293751
A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers.
The Journal of pathology May, 2012 | Pubmed ID: 22362584
Functional characterization of the 19q12 amplicon in grade III breast cancers.
Breast cancer research : BCR Mar, 2012 | Pubmed ID: 22433433
Molecular evidence in support of the neoplastic and precursor nature of microglandular adenosis.
Histopathology May, 2012 | Pubmed ID: 22486256
Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib.
Breast cancer research and treatment Sep, 2012 | Pubmed ID: 22875744
Mutation profiling of adenoid cystic carcinomas from multiple anatomical sites identifies mutations in the RAS pathway, but no KIT mutations.
Histopathology Mar, 2013 | Pubmed ID: 23398044
From integrative genomics to therapeutic targets.
Cancer research Jun, 2013 | Pubmed ID: 23740772
Genomic profiling of histological special types of breast cancer.
Breast cancer research and treatment Nov, 2013 | Pubmed ID: 24162157
Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity.
Cancer research Jan, 2014 | Pubmed ID: 24240700
Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast.
The Journal of pathology Apr, 2014 | Pubmed ID: 24395524
Integrative genomic and transcriptomic characterization of papillary carcinomas of the breast.
Molecular oncology Dec, 2014 | Pubmed ID: 25041824
Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C.
Genome research Nov, 2014 | Pubmed ID: 25122612
Metaplastic breast carcinomas display genomic and transcriptomic heterogeneity [corrected]. .
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Mar, 2015 | Pubmed ID: 25412848
SF3B1 mutations constitute a novel therapeutic target in breast cancer.
The Journal of pathology Mar, 2015 | Pubmed ID: 25424858
Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms.
Molecular oncology Aug, 2015 | Pubmed ID: 25825120
Corrigendum: metastatic breast carcinomas display genomic and transcriptomic heterogeneity.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Apr, 2015 | Pubmed ID: 25836989
Breast cancer heterogeneity: parallel evolution or conscious uncoupling?
The Journal of pathology Sep, 2015 | Pubmed ID: 25953517
Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification.
Genome biology May, 2015 | Pubmed ID: 25994018
Genomic landscape of adenoid cystic carcinoma of the breast.
The Journal of pathology Oct, 2015 | Pubmed ID: 26095796
An ecological measure of immune-cancer colocalization as a prognostic factor for breast cancer.
Breast cancer research : BCR Sep, 2015 | Pubmed ID: 26395345
The status of epidermal growth factor receptor in borderline ovarian tumours.
Oncotarget Mar, 2016 | Pubmed ID: 26870997
Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis.
PLoS medicine Feb, 2016 | Pubmed ID: 26881778
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
Cell reports Mar, 2016 | Pubmed ID: 26947069
Risk Stratification and Intrinsic Subtype Classification of Breast Cancer: a Multi-Parameter Test to Rule Them All?
Journal of the National Cancer Institute Sep, 2016 | Pubmed ID: 27130931
Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.
The Journal of pathology Nov, 2016 | Pubmed ID: 27512948
Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer.
Oncotarget Aug, 2016 | Pubmed ID: 27556857
Comparative proteomic assessment of matrisome enrichment methodologies.
The Biochemical journal Nov, 2016 | Pubmed ID: 27589945
Dual Targeting of PDGFRα and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors.
Cell reports Oct, 2016 | Pubmed ID: 27783942
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