Department of Chemistry and Biochemistry,
Molecular Biology Institute,
Jonsson Comprehensive Cancer Center
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Local chromatin structure at the ribosomal DNA causes replication fork pausing and genome instability in the absence of the S. cerevisiae DNA helicase Rrm3p.
Genes & development Mar, 2004 | Pubmed ID: 15037547
Saccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activities.
Molecular and cellular biology Apr, 2004 | Pubmed ID: 15060144
The S. cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes.
Genes & development Nov, 2006 | Pubmed ID: 17114583
The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis.
Developmental cell Jul, 2007 | Pubmed ID: 17609108
High-throughput generation of tagged stable cell lines for proteomic analysis.
Proteomics May, 2009 | Pubmed ID: 19405035
A specific form of phospho protein phosphatase 2 regulates anaphase-promoting complex/cyclosome association with spindle poles.
Molecular biology of the cell Mar, 2010 | Pubmed ID: 20089842
The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly.
Cell Dec, 2011 | Pubmed ID: 22153075
STARD9/Kif16a is a novel mitotic kinesin and antimitotic target.
Bioarchitecture Jan, 2012 | Pubmed ID: 22754624
An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity.
Cancer research May, 2013 | Pubmed ID: 23440422
Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors.
PloS one , 2014 | Pubmed ID: 25036740
p16 Protein and gigaxonin are associated with the ubiquitination of NFκB in cisplatin-induced senescence of cancer cells.
The Journal of biological chemistry Dec, 2014 | Pubmed ID: 25331947
A unique insertion in STARD9's motor domain regulates its stability.
Molecular biology of the cell Feb, 2015 | Pubmed ID: 25501367
Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens.
PLoS computational biology Mar, 2015 | Pubmed ID: 25826798
Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis.
Cell cycle (Georgetown, Tex.) , 2015 | Pubmed ID: 25830415
A LCMT1-PME-1 methylation equilibrium controls mitotic spindle size.
Cell cycle (Georgetown, Tex.) , 2015 | Pubmed ID: 25839665
Structures of potent anticancer compounds bound to tubulin.
Protein science : a publication of the Protein Society Jul, 2015 | Pubmed ID: 25970265
The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division.
Cell reports Jan, 2016 | Pubmed ID: 26748699
Proteomic Analysis of the Mammalian Katanin Family of Microtubule-severing Enzymes Defines Katanin p80 subunit B-like 1 (KATNBL1) as a Regulator of Mammalian Katanin Microtubule-severing.
Molecular & cellular proteomics : MCP May, 2016 | Pubmed ID: 26929214
Cystatin E/M Suppresses Tumor Cell Growth through Cytoplasmic Retention of NF-κB.
Molecular and cellular biology Jun, 2016 | Pubmed ID: 27090639
3D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping.
ACS chemical biology Aug, 2016 | Pubmed ID: 27285961
Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division.
The Journal of biological chemistry Aug, 2016 | Pubmed ID: 27378817
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