Diana Passaro

Haematopoietic Stem Cell Laboratory

The Francis Crick Institute

BIOGRAPHY

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PUBLICATIONS

A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death.

PloS one , 2011 | Pubmed ID: 21915281

Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progression.

EMBO molecular medicine 06, 2014 | Pubmed ID: 24778454

CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia.

Cancer cell Jun, 2015 | Pubmed ID: 26058076

Calcineurin/CXCR4 in T-ALL.

Oncoscience , 2015 | Pubmed ID: 26682242

Microenvironmental cues for T-cell acute lymphoblastic leukemia development.

Immunological reviews May, 2016 | Pubmed ID: 27088913

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments.

Nature 10, 2016 | Pubmed ID: 27750279

Versatile humanized niche model enables study of normal and malignant human hematopoiesis.

The Journal of clinical investigation Feb, 2017 | Pubmed ID: 28067666

Nuclear Factor Erythroid 2 Regulates Human HSC Self-Renewal and T Cell Differentiation by Preventing NOTCH1 Activation.

Stem cell reports Jul, 2017 | Pubmed ID: 28648895

Dynamic contrast-enhanced magnetic resonance imaging quantification of leukemia-induced changes in bone marrow vascular function.

Haematologica Aug, 2021 | Pubmed ID: 33764000

Integrated OMICs unveil the bone-marrow microenvironment in human leukemia.

Cell reports May, 2021 | Pubmed ID: 33979628

Endothelial heterogeneity in bone marrow: insights across development, adult life and leukemia.

Leukemia Jan, 2025 | Pubmed ID: 39528790

INSTITUTIONS

The Francis Crick Institute

Université Paris Cité UMR-S1016, INSERM U1016, CNRS UMR8104

JOVE ARTICLES

Bioengineering of Humanized Bone Marrow Microenvironments in Mouse and Their Visualization by Live Imaging

Diana Passaro^*,1,

Ander Abarrategi^*,1,

Katie Foster¹,

Linda Ariza-McNaughton¹,

Dominique Bonnet¹

¹Haematopoietic Stem Cell Laboratory, The Francis Crick Institute

Developmental Biology

Intravital Longitudinal Imaging of Vascular Dynamics in the Calvarial Bone Marrow

Aleria Duperray-Susini¹,

Thomas Guilbert²,

Jozsua Fodor³,

Julie Lesieur²,

Lakshmi Sandhow¹,

Pierre Bourdoncle²,

Diana Passaro¹

¹Leukemia and Niche Dynamics laboratory, Institut Cochin, Université Paris Cité UMR-S1016, INSERM U1016, CNRS UMR8104,

²IMAG'IC, Institut Cochin, Université Paris Cité UMR-S1016, INSERM U1016, CNRS UMR8104,

³YMETRY, Institut de Biologie de l'ENS (IBENS), École Normale Supérieure, Université PSL

Biology

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