Singapore Eye Research Institute
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Diabetes, hyperglycemia, and central corneal thickness: the Singapore Malay Eye Study.
Ophthalmology Jun, 2008 | Pubmed ID: 17964654
The prevalence and types of glaucoma in malay people: the Singapore Malay eye study.
Investigative ophthalmology & visual science Sep, 2008 | Pubmed ID: 18441307
Determinants of the optic cup to disc ratio in an Asian population: the Singapore Malay Eye Study (SiMES).
Archives of ophthalmology (Chicago, Ill. : 1960) Aug, 2008 | Pubmed ID: 18695105
Central corneal thickness and its associations with ocular and systemic factors: the Singapore Malay Eye Study.
American journal of ophthalmology Apr, 2009 | Pubmed ID: 19152872
The relationship of intraocular pressure with age, systolic blood pressure, and central corneal thickness in an asian population.
Investigative ophthalmology & visual science Sep, 2009 | Pubmed ID: 19458324
Relationship of retinal vascular caliber with optic disc and macular structure.
American journal of ophthalmology Sep, 2009 | Pubmed ID: 19481730
Age-related macular degeneration and risk of coronary heart disease and stroke: the Cardiovascular Health Study.
Ophthalmology Oct, 2009 | Pubmed ID: 19592102
Diabetes, metabolic abnormalities, and glaucoma.
Archives of ophthalmology (Chicago, Ill. : 1960) Oct, 2009 | Pubmed ID: 19822853
Methodology of the Singapore Indian Chinese Cohort (SICC) eye study: quantifying ethnic variations in the epidemiology of eye diseases in Asians.
Ophthalmic epidemiology Nov-Dec, 2009 | Pubmed ID: 19995197
Admixture mapping scans identify a locus affecting retinal vascular caliber in hypertensive African Americans: the Atherosclerosis Risk in Communities (ARIC) study.
PLoS genetics Apr, 2010 | Pubmed ID: 20419148
Refractive error, axial dimensions, and primary open-angle glaucoma: the Singapore Malay Eye Study.
Archives of ophthalmology (Chicago, Ill. : 1960) Jul, 2010 | Pubmed ID: 20625053
Hyperopic refractive error and shorter axial length are associated with age-related macular degeneration: the Singapore Malay Eye Study.
Investigative ophthalmology & visual science Dec, 2010 | Pubmed ID: 20671287
Is the pediatric quality of life inventory valid for use in preschool children with refractive errors?
Optometry and vision science : official publication of the American Academy of Optometry Nov, 2010 | Pubmed ID: 20852452
The heritability and sibling risk of angle closure in Asians.
Ophthalmology Mar, 2011 | Pubmed ID: 21035870
Clinical practice. Retinal-vein occlusion.
The New England journal of medicine Nov, 2010 | Pubmed ID: 21105795
Novel anterior-chamber angle measurements by high-definition optical coherence tomography using the Schwalbe line as the landmark.
The British journal of ophthalmology Jul, 2011 | Pubmed ID: 21183513
Determinants of image quality of Heidelberg Retina Tomography II and its association with optic disc parameters in a population-based setting.
American journal of ophthalmology Apr, 2011 | Pubmed ID: 21257147
Determinants of corneal biomechanical properties in an adult Chinese population.
Ophthalmology Jul, 2011 | Pubmed ID: 21333357
Diabetic retinopathy in 2011: further insights from new epidemiological studies and clinical trials.
Diabetes care Apr, 2011 | Pubmed ID: 21447672
Comparison of ocular response analyzer parameters in chinese subjects with primary angle-closure and primary open-angle glaucoma.
Archives of ophthalmology (Chicago, Ill. : 1960) Apr, 2011 | Pubmed ID: 21482869
Prevalence and causes of visual impairment and blindness in an urban Indian population: the Singapore Indian Eye Study.
Ophthalmology Sep, 2011 | Pubmed ID: 21621261
Cataract prevalence varies substantially with assessment systems: comparison of clinical and photographic grading in a population-based study.
Ophthalmic epidemiology Aug, 2011 | Pubmed ID: 21780875
The microvasculature in chronic kidney disease.
Clinical journal of the American Society of Nephrology : CJASN Aug, 2011 | Pubmed ID: 21784828
Emerging evidence concerning systemic safety of anti-VEGF agents--should ophthalmologists be concerned?
American journal of ophthalmology Sep, 2011 | Pubmed ID: 21855670
Racial differences in the prevalence of diabetes but not diabetic retinopathy in a multi-ethnic Asian population.
Investigative ophthalmology & visual science Sep, 2011 | Pubmed ID: 21862647
Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe).
Investigative ophthalmology & visual science Sep, 2011 | Pubmed ID: 21873659
Independent impact of area-level socioeconomic measures on visual impairment.
Investigative ophthalmology & visual science Nov, 2011 | Pubmed ID: 21969296
Identification of four novel variants that influence central corneal thickness in multi-ethnic Asian populations.
Human molecular genetics Jan, 2012 | Pubmed ID: 21984434
Determinants of quantitative optic nerve measurements using spectral domain optical coherence tomography in a population-based sample of non-glaucomatous subjects.
Investigative ophthalmology & visual science Dec, 2011 | Pubmed ID: 22039236
The prevalence and risk factors of ocular trauma: the Singapore Indian eye study.
Ophthalmic epidemiology Dec, 2011 | Pubmed ID: 22053838
Retinal microvascular calibre and risk of incident diabetes: the multi-ethnic study of atherosclerosis.
Diabetes research and clinical practice Feb, 2012 | Pubmed ID: 22088792
Lipids and diabetic retinopathy.
Expert opinion on biological therapy Jan, 2012 | Pubmed ID: 22122357
Impact of Bilateral Open and Closed-angle Glaucoma on Glaucoma-specific Functioning in Asians.
Journal of glaucoma Dec, 2011 | Pubmed ID: 22157514
Prevalence of and risk factors for age-related macular degeneration in a multiethnic Asian cohort.
Archives of ophthalmology (Chicago, Ill. : 1960) Apr, 2012 | Pubmed ID: 22159171
Prevalence and risk factors of epiretinal membrane in Asian Indians.
Investigative ophthalmology & visual science Feb, 2012 | Pubmed ID: 22247478
Asian age-related macular degeneration phenotyping study: rationale, design and protocol of a prospective cohort study.
Clinical & experimental ophthalmology Sep-Oct, 2012 | Pubmed ID: 22299650
Global prevalence and major risk factors of diabetic retinopathy.
Diabetes care Mar, 2012 | Pubmed ID: 22301125
Comparison of scanning laser ophthalmoscopy and high-definition optical coherence tomography measurements of optic disc parameters.
The British journal of ophthalmology Apr, 2012 | Pubmed ID: 22322203
Impact of migration and acculturation on prevalence of type 2 diabetes and related eye complications in Indians living in a newly urbanised society.
PloS one , 2012 | Pubmed ID: 22506053
Age-related macular degeneration and long-term risk of stroke subtypes.
Stroke Jun, 2012 | Pubmed ID: 22535267
Age-related macular degeneration.
Lancet (London, England) May, 2012 | Pubmed ID: 22559899
Prevalence and risk factors of diabetic retinopathy in migrant Indians in an urbanized society in Asia: the Singapore Indian eye study.
Ophthalmology Oct, 2012 | Pubmed ID: 22709419
Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals.
Disease models & mechanisms Jul, 2012 | Pubmed ID: 22730475
Pentosidine levels in nonproteinuric diabetes associated with both low estimated glomerular filtration rate and cataract.
Diabetes, metabolic syndrome and obesity : targets and therapy , 2012 | Pubmed ID: 22807634
Determinants of ganglion cell-inner plexiform layer thickness measured by high-definition optical coherence tomography.
Investigative ophthalmology & visual science Aug, 2012 | Pubmed ID: 22836772
Language barrier and its relationship to diabetes and diabetic retinopathy.
BMC public health Sep, 2012 | Pubmed ID: 22974298
Retinal microvascular signs and risk of stroke: the Multi-Ethnic Study of Atherosclerosis (MESA).
Stroke Dec, 2012 | Pubmed ID: 23111439
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
Nature genetics Feb, 2013 | Pubmed ID: 23291589
Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.
PloS one , 2013 | Pubmed ID: 23326517
Lack of awareness of common eye conditions in the community.
Ophthalmic epidemiology , 2013 | Pubmed ID: 23350556
Genome-wide association study of retinopathy in individuals without diabetes.
PloS one , 2013 | Pubmed ID: 23393555
How much eye care services do Asian populations need? Projection from the Singapore Epidemiology of Eye Disease (SEED) study.
Investigative ophthalmology & visual science Mar, 2013 | Pubmed ID: 23439593
Racial variations in the prevalence of refractive errors in the United States: the multi-ethnic study of atherosclerosis.
American journal of ophthalmology Jun, 2013 | Pubmed ID: 23453694
Associations of iris structural measurements in a Chinese population: the Singapore Chinese Eye Study.
Investigative ophthalmology & visual science Apr, 2013 | Pubmed ID: 23538059
Validity of a new optic disc grading software for use in clinical and epidemiological research.
Clinical & experimental ophthalmology Apr, 2013 | Pubmed ID: 23566165
Marital status and its relationship with the risk and pattern of visual impairment in a multi-ethnic Asian population.
Journal of public health (Oxford, England) Mar, 2014 | Pubmed ID: 23658389
Genetic loci for retinal arteriolar microcirculation.
PloS one , 2013 | Pubmed ID: 23776548
Retinal vascular fractal and blood pressure in a multiethnic population.
Journal of hypertension Oct, 2013 | Pubmed ID: 23787404
Treatment of age-related macular degeneration.
Lancet (London, England) Oct, 2013 | Pubmed ID: 23870812
Cardio-metabolic risk factors and prehypertension in persons without diabetes, hypertension, and cardiovascular disease.
BMC public health Aug, 2013 | Pubmed ID: 23919264
Myopia and age-related cataract: a systematic review and meta-analysis.
American journal of ophthalmology Nov, 2013 | Pubmed ID: 23938120
Epidemiology and disease burden of pathologic myopia and myopic choroidal neovascularization: an evidence-based systematic review.
American journal of ophthalmology Jan, 2014 | Pubmed ID: 24099276
Relationship between ganglion cell-inner plexiform layer and optic disc/retinal nerve fibre layer parameters in non-glaucomatous eyes.
The British journal of ophthalmology Dec, 2013 | Pubmed ID: 24123901
The economic cost of myopia in adults aged over 40 years in Singapore.
Investigative ophthalmology & visual science Nov, 2013 | Pubmed ID: 24159089
Challenges in elucidating the genetics of diabetic retinopathy.
JAMA ophthalmology Jan, 2014 | Pubmed ID: 24201651
Retinal vascular caliber and the development of hypertension: a meta-analysis of individual participant data.
Journal of hypertension Feb, 2014 | Pubmed ID: 24322199
RADIANCE: a randomized controlled study of ranibizumab in patients with choroidal neovascularization secondary to pathologic myopia.
Ophthalmology Mar, 2014 | Pubmed ID: 24326106
The prognostic role of body mass index on mortality amongst the middle-aged and elderly: a competing risk analysis.
Diabetes research and clinical practice Jan, 2014 | Pubmed ID: 24382466
Prevalence and causes of vision loss in East Asia: 1990-2010.
The British journal of ophthalmology May, 2014 | Pubmed ID: 24390167
Effects of simvastatin on retinal structure and function of a high-fat atherogenic mouse model of thickened Bruch's membrane.
Investigative ophthalmology & visual science Jan, 2014 | Pubmed ID: 24398101
Assessment of iris surface features and their relationship with iris thickness in Asian eyes.
Ophthalmology May, 2014 | Pubmed ID: 24405741
Personalized Medicine in Ophthalmology: From Pharmacogenetic Biomarkers to Therapeutic and Dosage Optimization.
Journal of personalized medicine , 2013 | Pubmed ID: 24624293
Genetic risk, ethnic variations and pharmacogenetic biomarkers in age-related macular degeneration and polypoidal choroidal vasculopathy.
Expert review of ophthalmology Apr, 2013 | Pubmed ID: 24860613
Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
Circulation. Cardiovascular genetics Jun, 2014 | Pubmed ID: 24951664
Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis.
Ophthalmology Nov, 2014 | Pubmed ID: 24974815
Myopic choroidal neovascularisation: current concepts and update on clinical management.
The British journal of ophthalmology Mar, 2015 | Pubmed ID: 24990871
Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study.
Investigative ophthalmology & visual science Sep, 2014 | Pubmed ID: 25205864
Development and reliability of retinal arteriolar central light reflex quantification system: a new approach for severity grading.
Investigative ophthalmology & visual science Oct, 2014 | Pubmed ID: 25358734
Glaucoma and associated visual acuity and field loss significantly affect glaucoma-specific psychosocial functioning.
Ophthalmology Mar, 2015 | Pubmed ID: 25444640
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.
Nature communications Jan, 2015 | Pubmed ID: 25631608
Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.
Circulation. Cardiovascular genetics Apr, 2015 | Pubmed ID: 25663218
Aggregate Effects of Intraocular Pressure and Cup-to-Disc Ratio Genetic Variants on Glaucoma in a Multiethnic Asian Population.
Ophthalmology Jun, 2015 | Pubmed ID: 25745874
Lens status influences the association between CFH polymorphisms and age-related macular degeneration: findings from two population-based studies in Singapore.
PloS one , 2015 | Pubmed ID: 25786237
The Impact of Lens Vault on Visual Acuity and Refractive Error: Implications for Management of Primary Angle-closure Glaucoma.
Journal of glaucoma Mar, 2016 | Pubmed ID: 25943738
Prevalence and determinants of undiagnosed diabetic retinopathy and vision-threatening retinopathy in a multiethnic Asian cohort: the Singapore Epidemiology of Eye Diseases (SEED) study.
The British journal of ophthalmology Dec, 2015 | Pubmed ID: 25953847
Determinants of optical coherence tomography-derived minimum neuroretinal rim width in a normal Chinese population.
Investigative ophthalmology & visual science May, 2015 | Pubmed ID: 26024117
African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans.
Investigative ophthalmology & visual science Jun, 2015 | Pubmed ID: 26098467
Retinal Vessel Analysis as a Tool to Quantify Risk of Diabetic Retinopathy.
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) Jul-Aug, 2012 | Pubmed ID: 26107480
Retinal microvascular calibre and risk of diabetes mellitus: a systematic review and participant-level meta-analysis.
Diabetologia Nov, 2015 | Pubmed ID: 26232097
Polypoidal Choroidal Vasculopathy in Asians.
Journal of clinical medicine Apr, 2015 | Pubmed ID: 26239448
Visual Impairment in White, Chinese, Black, and Hispanic Participants from the Multi-Ethnic Study of Atherosclerosis Cohort.
Ophthalmic epidemiology , 2015 | Pubmed ID: 26395659
Assessment of the psychometric properties of the Chinese Impact of Vision Impairment questionnaire in a population-based study: findings from the Singapore Chinese Eye Study.
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation Apr, 2016 | Pubmed ID: 26420045
Ocular Fundus Photography as a Tool to Study Stroke and Dementia.
Seminars in neurology Oct, 2015 | Pubmed ID: 26444393
Composite Measures of Individual and Area-Level Socio-Economic Status Are Associated with Visual Impairment in Singapore.
PloS one , 2015 | Pubmed ID: 26555141
Novel Genetic Loci Associated With Retinal Microvascular Diameter.
Circulation. Cardiovascular genetics Feb, 2016 | Pubmed ID: 26567291
Epidemiology of diabetic retinopathy, diabetic macular edema and related vision loss.
Eye and vision (London, England) , 2015 | Pubmed ID: 26605370
Retinal Vein Occlusion in a Multi-Ethnic Asian Population: The Singapore Epidemiology of Eye Disease Study.
Ophthalmic epidemiology , 2016 | Pubmed ID: 26751637
Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma.
Nature genetics Feb, 2016 | Pubmed ID: 26752265
Joint Effects of Intraocular Pressure and Myopia on Risk of Primary Open-Angle Glaucoma: The Singapore Epidemiology of Eye Diseases Study.
Scientific reports Jan, 2016 | Pubmed ID: 26758554
Determinants of pupil diameters and pupil dynamics in an adult Chinese population.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie May, 2016 | Pubmed ID: 26810838
Retinal ganglion cell neuronal damage in diabetes and diabetic retinopathy.
Clinical & experimental ophthalmology May, 2016 | Pubmed ID: 26872562
Incidence of Age-Related Macular Degeneration in a Multi-Ethnic United States Population: The Multi-Ethnic Study of Atherosclerosis.
Ophthalmology Jun, 2016 | Pubmed ID: 26896123
Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.
Nature genetics May, 2016 | Pubmed ID: 27064256
Increased Burden of Vision Impairment and Eye Diseases in Persons with Chronic Kidney Disease - A Population-Based Study.
EBioMedicine Mar, 2016 | Pubmed ID: 27077127
Diabetic retinopathy.
Nature reviews. Disease primers 03, 2016 | Pubmed ID: 27159554
Ten Emerging Trends in the Epidemiology of Diabetic Retinopathy.
Ophthalmic epidemiology Aug, 2016 | Pubmed ID: 27355693
Characterization of Fatty Acid Binding Protein 7 (FABP7) in the Murine Retina.
Investigative ophthalmology & visual science Jun, 2016 | Pubmed ID: 27367508
Posterior Eye Shape Measurement With Retinal OCT Compared to MRI.
Investigative ophthalmology & visual science Jul, 2016 | Pubmed ID: 27409473
Inter-Relationships Between Retinal Vascular Caliber, Retinal Nerve Fiber Layer Thickness, and Glaucoma: A Mediation Analysis Approach.
Investigative ophthalmology & visual science Jul, 2016 | Pubmed ID: 27421069
Sex-Specific Association of Obstructive Sleep Apnea With Retinal Microvascular Signs: The Multi-Ethnic Study of Atherosclerosis.
Journal of the American Heart Association Jul, 2016 | Pubmed ID: 27451457
Association of Vision Impairment and Major Eye Diseases With Mobility and Independence in a Chinese Population.
JAMA ophthalmology Oct, 2016 | Pubmed ID: 27467140
The impact of typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy on vision-related quality of life in Asian patients.
The British journal of ophthalmology May, 2017 | Pubmed ID: 27485722
Vision impairment and major eye diseases reduce vision-specific emotional well-being in a Chinese population.
The British journal of ophthalmology May, 2017 | Pubmed ID: 27565988
The Association Between Retinal Neuronal Layer and Brain Structure is Disrupted in Patients with Cognitive Impairment and Alzheimer's Disease.
Journal of Alzheimer's disease : JAD Sep, 2016 | Pubmed ID: 27567815
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
Nature genetics Sep, 2016 | Pubmed ID: 27618452
Novel genetic loci underlying human intracranial volume identified through genome-wide association.
Nature neuroscience Dec, 2016 | Pubmed ID: 27694991
Association of Changes in Visual Acuity With Vision-Specific Functioning in the Singapore Malay Eye Study.
JAMA ophthalmology Nov, 2016 | Pubmed ID: 27711912
Rationale and Methodology for a Community-Based Study of Diabetic Retinopathy in an Indonesian Population with Type 2 Diabetes Mellitus: The Jogjakarta Eye Diabetic Study in the Community.
Ophthalmic epidemiology Feb, 2017 | Pubmed ID: 28032809
Evidence of Microvascular Changes in the Retina following Kawasaki Disease.
Scientific reports Jan, 2017 | Pubmed ID: 28094311
Novel genetic loci associated with hippocampal volume.
Nature communications Jan, 2017 | Pubmed ID: 28098162
Retinal angiomatous proliferation.
Survey of ophthalmology Jul - Aug, 2017 | Pubmed ID: 28189495
A nationwide cohort study of cigarette smoking and risk of neovascular age-related macular degeneration in East Asian men.
The British journal of ophthalmology Oct, 2017 | Pubmed ID: 28292774
Prevalence and Determinants of Suboptimal Vitamin D Levels in a Multiethnic Asian Population.
Nutrients Mar, 2017 | Pubmed ID: 28327512
Ethnic Differences in the Association Between Age-Related Macular Degeneration and Vision-Specific Functioning.
JAMA ophthalmology May, 2017 | Pubmed ID: 28358956
Urinary Isoprostane Levels and Age-Related Macular Degeneration.
Investigative ophthalmology & visual science May, 2017 | Pubmed ID: 28492872
Six-Year Incidence of Age-Related Macular Degeneration in Asian Malays: The Singapore Malay Eye Study.
Ophthalmology Sep, 2017 | Pubmed ID: 28501376
Diabetic macular oedema: evidence-based treatment recommendations for Asian countries.
Clinical & experimental ophthalmology May, 2017 | Pubmed ID: 28558152
Change in vision-related quality of life and influencing factors in Asians receiving treatment for neovascular age-related macular degeneration.
The British journal of ophthalmology Jun, 2017 | Pubmed ID: 28659392
Combined poor diabetes control indicators are associated with higher risks of diabetic retinopathy and macular edema than poor glycemic control alone.
PloS one , 2017 | Pubmed ID: 28662119
Inter-relationship between visual symptoms, activity limitation and psychological functioning in patients with diabetic retinopathy.
The British journal of ophthalmology Sep, 2017 | Pubmed ID: 28928266
Efficacy and Safety of Ranibizumab With or Without Verteporfin Photodynamic Therapy for Polypoidal Choroidal Vasculopathy: A Randomized Clinical Trial.
JAMA ophthalmology Oct, 2017 | Pubmed ID: 28983556
Victor T.T. Chan1,
Tiffany H.K. Tso1,
Fangyao Tang1,
Clement Tham1,
Vincent Mok2,3,4,
Christopher Chen5,6,
Tien Y. Wong7,8,
Carol Y. Cheung1
1Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong,
2Department of Medicine & Therapeutics, The Chinese University of Hong Kong,
3Therese Pei Fong Chow Research Centre for Prevention of Dementia, The Chinese University of Hong Kong,
4Gerald Choa Neuroscience Centre, The Chinese University of Hong Kong,
5Memory Aging and Cognition Centre, National University Health System,
6Department of Pharmacology, National University of Singapore,
7Singapore Eye Research Institute, Singapore National Eye Centre,
8Duke-NUS Medical School, National University of Singapore
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