Nikolai Klymiuk

Characterization of porcine endogenous retrovirus gamma pro-pol nucleotide sequences.

Recombination analysis of human-tropic porcine endogenous retroviruses.

Characterization of endogenous retroviruses in sheep.

Reliable classification and recombination analysis of porcine endogenous retroviruses.

Phylogeny, recombination and expression of porcine endogenous retrovirus gamma2 nucleotide sequences.

Concise classification of the genomic porcine endogenous retroviral gamma1 load to defined lineages.

Genomic, tissue expression, and protein characterization of pCLCA1, a putative modulator of cystic fibrosis in the pig.

Genetic modification of pigs as organ donors for xenotransplantation.

Transgenic pigs for xenotransplantation: selection of promoter sequences for reliable transgene expression.

Transgenic pigs as models for translational biomedical research.

Tissue and cellular expression patterns of porcine CFTR: similarities to and differences from human CFTR.

First inducible transgene expression in porcine large animal models.

The porcine chloride channel calcium-activated family member pCLCA4a mirrors lung expression of the human hCLCA4.

Xenografted islet cell clusters from INSLEA29Y transgenic pigs rescue diabetes and prevent immune rejection in humanized mice.

Potential of primary kidney cells for somatic cell nuclear transfer mediated transgenesis in pig.

Permanent neonatal diabetes in INS(C94Y) transgenic pigs.

Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set.

Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle.

Activation of the lectin pathway of complement in pig-to-human xenotransplantation models.

Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs.

Homologous recombination contributes to the repair of zinc-finger-nuclease induced double strand breaks in pig primary cells and facilitates recombination with exogenous DNA.

Complement dependent early immunological responses during ex vivo xenoperfusion of hCD46/HLA-E double transgenic pig forelimbs with human blood.

Pig-to-baboon heterotopic heart transplantation--exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimens.

Virus safety of islet cell transplantation from transgenic pigs to marmosets.

Transgenic Expression of Human CD46 on Porcine Endothelium: Effect on Coagulation and Fibrinolytic Cascades During Ex Vivo Human-to-Pig Limb Xenoperfusions.

Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b without Apparent Phenotype.

Engraftment and reversal of diabetes after intramuscular transplantation of neonatal porcine islet-like clusters.

Tailored Pig Models for Preclinical Efficacy and Safety Testing of Targeted Therapies.

Computed Tomography (CT) Scanning Facilitates Early Identification of Neonatal Cystic Fibrosis Piglets.

Pre-clinical heterotopic intrathoracic heart xenotransplantation: a possibly useful clinical technique.

Inhibition of complement component C5 prevents clotting in an ex vivo model of xenogeneic activation of coagulation.

Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft.

Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation.

Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs.

Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy.

Direct introduction of gene constructs into the pronucleus-like structure of cloned embryos: a new strategy for the generation of genetically modified pigs.

Transgenic expression of human leukocyte antigen-E attenuates GalKO.hCD46 porcine lung xenograft injury.

Vessel network architecture of adult human islets promotes distinct cell-cell interactions in situ and is altered after transplantation.

Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood.