St. Vincent's Hospital Melbourne
2 ARTICLES PUBLISHED IN JoVE
Medicine
Assessment of the Anticoagulant and Anti-inflammatory Properties of Endothelial Cells Using 3D Cell Culture and Non-anticoagulated Whole Blood
Riccardo Sfriso 1,2, Anjan Bongoni 3, Yara Banz 4, Nikolai Klymiuk 5, Eckhard Wolf 5, Robert Rieben 1
1Department of Clinical Research, University of Bern, 2Graduate School for Cellular and Biomedical Sciences, University of Bern, 3Immunology Research Centre, St. Vincent's Hospital Melbourne, 4Institute of Pathology, University of Bern, 5Institute of Molecular Animal Breeding and Biotechnology, Ludwig-Maximilian University
We present an in vitro model which allows the study and analysis of coagulation in whole, non-anticoagulated blood. Anticoagulation in the system depends on the natural anticoagulation effect of healthy endothelial cells and endothelial cell activation will result in clotting.
Education
Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
Andria Pelentritou 1, Levin Kuhlmann 1, John Cormack 2, Will Woods 3, Jamie Sleigh 4, David Liley 1
1Centre for Human Psychopharmacology, Swinburne University of Technology, 2Department of Anaesthesia and Pain Management, St. Vincent's Hospital Melbourne, 3Brain and Psychological Science Research Centre, Swinburne University of Technology, 4Department of Anaesthesiology, University of Auckland
Simultaneous magnetoencephalography and electroencephalography provides a useful tool to search for common and distinct macro-scale mechanisms of reductions in consciousness induced by different anesthetics. This paper illustrates the empirical methods underlying the recording of such data from healthy humans during N-Methyl-D-Aspartate-(NMDA)-receptor-antagonist-based anesthesia during inhalation of nitrous oxide and xenon.
