Centre for Regenerative Medicine,
Department of Life Sciences,
Centre for Regenerative Medicine, Department of Life Sciences
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Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2006 | Pubmed ID: 16432223
Site-specific integration into the human genome: ready for clinical application?
Rejuvenation research , 2006 | Pubmed ID: 17105384
Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells.
Nature medicine Dec, 2006 | Pubmed ID: 17115047
Beta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination.
The Journal of cell biology Jun, 2007 | Pubmed ID: 17576799
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy.
The Journal of clinical investigation Aug, 2007 | Pubmed ID: 17671653
Tracking gene-modified T cells in vivo.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19110640
Transcription factor binding sites are genetic determinants of retroviral integration in the human genome.
PloS one , 2009 | Pubmed ID: 19238208
Transcriptional enhancers induce insertional gene deregulation independently from the vector type and design.
Molecular therapy : the journal of the American Society of Gene Therapy May, 2009 | Pubmed ID: 19293778
High-definition mapping of retroviral integration sites defines the fate of allogeneic T cells after donor lymphocyte infusion.
PloS one , 2010 | Pubmed ID: 21203516
Site-specific integration by the adeno-associated virus rep protein.
Current gene therapy Oct, 2011 | Pubmed ID: 21827397
Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.
Nucleic acids research Mar, 2013 | Pubmed ID: 23275534
Targeted gene addition in human epithelial stem cells by zinc-finger nuclease-mediated homologous recombination.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2013 | Pubmed ID: 23760447
Long-term stability and safety of transgenic cultured epidermal stem cells in gene therapy of junctional epidermolysis bullosa.
Stem cell reports Jan, 2014 | Pubmed ID: 24511464
Long-term skin regeneration from a gene-targeted human epidermal stem cell clone.
Molecular therapy : the journal of the American Society of Gene Therapy Nov, 2014 | Pubmed ID: 25365983
Genomic analysis of Sleeping Beauty transposon integration in human somatic cells.
PloS one , 2014 | Pubmed ID: 25390293
A single epidermal stem cell strategy for safe ex vivo gene therapy.
EMBO molecular medicine Apr, 2015 | Pubmed ID: 25724200
Nuclear architecture dictates HIV-1 integration site selection.
Nature May, 2015 | Pubmed ID: 25731161
Design of a regulated lentiviral vector for hematopoietic stem cell gene therapy of globoid cell leukodystrophy.
Molecular therapy. Methods & clinical development , 2015 | Pubmed ID: 26509184
Transcriptionally regulated and nontoxic delivery of the hyperactive Sleeping Beauty Transposase.
Molecular therapy. Methods & clinical development , 2016 | Pubmed ID: 27574698
In vivo Editing of the Human Mutant Rhodopsin Gene by Electroporation of Plasmid-based CRISPR/Cas9 in the Mouse Retina.
Molecular therapy. Nucleic acids Nov, 2016 | Pubmed ID: 27874856
Correction of Recessive Dystrophic Epidermolysis Bullosa by Transposon-Mediated Integration of COL7A1 in Transplantable Patient-Derived Primary Keratinocytes.
The Journal of investigative dermatology Apr, 2017 | Pubmed ID: 28027893
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