Alessandra Recchia

Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells.

Site-specific integration into the human genome: ready for clinical application?

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells.

Beta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination.

Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy.

Tracking gene-modified T cells in vivo.

Transcription factor binding sites are genetic determinants of retroviral integration in the human genome.

Transcriptional enhancers induce insertional gene deregulation independently from the vector type and design.

High-definition mapping of retroviral integration sites defines the fate of allogeneic T cells after donor lymphocyte infusion.

Site-specific integration by the adeno-associated virus rep protein.

Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.

Targeted gene addition in human epithelial stem cells by zinc-finger nuclease-mediated homologous recombination.

Long-term stability and safety of transgenic cultured epidermal stem cells in gene therapy of junctional epidermolysis bullosa.

Long-term skin regeneration from a gene-targeted human epidermal stem cell clone.

Genomic analysis of Sleeping Beauty transposon integration in human somatic cells.

A single epidermal stem cell strategy for safe ex vivo gene therapy.

Nuclear architecture dictates HIV-1 integration site selection.

Design of a regulated lentiviral vector for hematopoietic stem cell gene therapy of globoid cell leukodystrophy.

Transcriptionally regulated and nontoxic delivery of the hyperactive Sleeping Beauty Transposase.

In vivo Editing of the Human Mutant Rhodopsin Gene by Electroporation of Plasmid-based CRISPR/Cas9 in the Mouse Retina.

Correction of Recessive Dystrophic Epidermolysis Bullosa by Transposon-Mediated Integration of COL7A1 in Transplantable Patient-Derived Primary Keratinocytes.